CD51 (ITGAV) (NM_001145000) Human Untagged Clone

CAT#: SC326313

ITGAV (untagged)-Human integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) (ITGAV), transcript variant 3



  "NM_001145000" in other vectors (4)

CNY 10,450.00


货期*
7周

规格
    • 10 ug

Product images

经常一起买 (4)
Rabbit Monoclonal antibody against CD51 / Integrin alpha-V (ITGAV)
    • 100 ul

CNY 6,248.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms CD51; MSK8; VNRA; VTNR
Vector pCMV6 series
Sequence Data
>NCBI ORF sequence for NM_001145000, the custom clone sequence may differ by one or more nucleotides
ATGGCTTTTCCGCCGCGGCGACGGCTGCGCCTCGGTCCCCGCGGCCTCCCGCTTCTTCTC
TCGGGACTCCTGCTACCTCTGTGCCGCGCCTTCAACCTAGACGTGGACAGTCCTGCCGAG
TACTCTGGCCCCGAGGGAAGTTACTTCGGCTTCGCCGTGGATTTCTTCGTGCCCAGCGCG
TCTTCCCGGATGTTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATT
GTGGAAGGAGGGCAGGTCCTCAAATGTGACTGGTCTTCTACCCGCCGGTGCCAGCCAATT
GAATTTGATGCAACAGGCAATAGAGATTATGCCAAGGATGATCCATTGGAATTTAAGTCC
CATCAGTGGTTTGGAGCATCTGTGAGGTCGAAACAGGATAAAATTTTGGCCTGTGCCCCA
TTGTACCATTGGAGAACTGAGATGAAACAGGAGCGAGAGCCTGTTGGAACATGCTTTCTT
CAAGATGGAACAAAGACTGTTGAGTATGCTCCATGTAGATCACGTCAGCTTATTTCGGAT
CAAGTGGCAGAAATCGTATCTAAATACGACCCCAATGTTTACAGCATCAAGTATAATAAC
CAATTAGCAACTCGGACTGCACAAGCTATTTTTGATGACAGCTATTTGGGTTATTCTGTG
GCTGTCGGAGATTTCAATGGTGATGGCATAGATGACTTTGTTTCAGGAGTTCCAAGAGCA
GCAAGGACTTTGGGAATGGTTTATATTTATGATGGGAAGAACATGTCCTCCTTATACAAT
TTTACTGGCGAGCAGATGGCTGCATATTTCGGATTTTCTGTAGCTGCCACTGACATTAAT
GGAGATGATTATGCAGATGTGTTTATTGGAGCACCTCTCTTCATGGATCGTGGCTCTGAT
GGCAAACTCCAAGAGGTGGGGCAGGTCTCAGTGTCTCTACAGAGAGCTTCAGGAGACTTC
CAGACGACAAAGCTGAATGGATTTGAGGTCTTTGCACGGTTTGGCAGTGCCATAGCTCCT
TTGGGAGATCTGGACCAGGATGGTTTCAATGATATTGCAATTGCTGCTCCATATGGGGGT
GAAGATAAAAAAGGAATTGTTTATATCTTCAATGGAAGATCAACAGGCTTGAACGCAGTC
CCATCTCAAATCCTTGAAGGGCAGTGGGCTGCTCGAAGCATGCCACCAAGCTTTGGCTAT
TCAATGAAAGGAGCCACAGATATAGACAAAAATGGATATCCAGACTTAATTGTAGGAGCT
TTTGGTGTAGATCGAGCTATCTTATACAGGGCCAGACCAGTTATCACTGTAAATGCTGGT
CTTGAAGTGTACCCTAGCATTTTAAATCAAGACAATAAAACCTGCTCACTGCCTGGAACA
GCTCTCAAAGTTTCCTGTTTTAATGTTAGGTTCTGCTTAAAGGCAGATGGCAAAGGAGTA
CTTCCCAGGAAACTTAATTTCCAGGTGGAACTTCTTTTGGATAAACTCAAGCAAAAGGGA
GCAATTCGACGAGCACTGTTTCTCTACAGCAGGTCCCCAAGTCACTCCAAGAACATGACT
ATTTCAAGGGGGGGACTGATGCAGTGTGAGGAATTGATAGCGTATCTGCGGGATGAATCT
GAATTTAGAGACAAACTCACTCCAATTACTATTTTTATGGAATATCGGTTGGATTATAGA
ACAGCTGCTGATACAACAGGCTTGCAACCCATTCTTAACCAGTTCACGCCTGCTAACATT
AGTCGACAGGCTCACATTCTACTTGACTGTGGTGAAGACAATGTCTGTAAACCCAAGCTG
GAAGTTTCTGTAGATAGTGATCAAAAGAAGATCTATATTGGGGATGACAACCCTCTGACA
TTGATTGTTAAGGCTCAGAATCAAGGAGAAGGTGCCTACGAAGCTGAGCTCATCGTTTCC
ATTCCACTGCAGGCTGATTTCATCGGGGTTGTCCGAAACAATGAAGCCTTAGCAAGACTT
TCCTGTGCATTTAAGACAGAAAACCAAACTCGCCAGGTGGTATGTGACCTTGGAAACCCA
ATGAAGGCTGGAACTCAACTCTTAGCTGGTCTTCGTTTCAGTGTGCACCAGCAGTCAGAG
ATGGATACTTCTGTGAAATTTGACTTACAAATCCAAAGCTCAAATCTATTTGACAAAGTA
AGCCCAGTTGTATCTCACAAAGTTGATCTTGCTGTTTTAGCTGCAGTTGAGATAAGAGGA
GTCTCGAGTCCTGATCATATCTTTCTTCCGATTCCAAACTGGGAGCACAAGGAGAACCCT
GAGACTGAAGAAGATGTTGGGCCAGTTGTTCAGCACATCTATGAGCTGAGAAACAATGGT
CCAAGTTCATTCAGCAAGGCAATGCTCCATCTTCAGTGGCCTTACAAATATAATAATAAC
ACTCTGTTGTATATCCTTCATTATGATATTGATGGACCAATGAACTGCACTTCAGATATG
GAGATCAACCCTTTGAGAATTAAGATCTCATCTTTGCAAACAACTGAAAAGAATGACACG
GTTGCCGGGCAAGGTGAGCGGGACCATCTCATCACTAAGCGGGATCTTGCCCTCAGTGAA
GGAGATATTCACACTTTGGGTTGTGGAGTTGCTCAGTGCTTGAAGATTGTCTGCCAAGTT
GGGAGATTAGACAGAGGAAAGAGTGCAATCTTGTACGTAAAGTCATTACTGTGGACTGAG
ACTTTTATGAATAAAGAAAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTT
AATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGATATCACCAACTCCACATTG
GTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTG
ATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTAC
AGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTT
CAACCTCATGAAAATGGTGAAGGAAACTCAGAAACT
Restriction Sites Please inquire     
ACCN NM_001145000
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001145000.1, NP_001138472.1
RefSeq Size 6939 bp
RefSeq ORF 3039 bp
Locus ID 3685
UniProt ID P06756
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer
Gene Summary The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
Transcript Variant: This variant (3) lacks two alternate in-frame exons in the coding region compared to variant 1. This results in a shorter protein (isoform 3) compared to isoform 1. It is not known whether this isoform (3) is proteolytically processed in the same manner as isoform 1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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