RbAp48 (RBBP4) (NM_001135255) Human Untagged Clone
CAT#: SC325084
RBBP4 (untagged)-Human retinoblastoma binding protein 4 (RBBP4), transcript variant 2
CNY 7,220.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | lin-53; NURF55; RBAP48 |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_001135255, the custom clone sequence may differ by one or more nucleotides
ATGGCCGACAAGGAAGCCTTCGACGACGCAGTGGAAGAACGAGTGATCAACGAGGAATAC AAAATATGGAAAAAGAACACCCCTTTTCTTTATGATTTGGTGATGACCCATGCTCTGGAG TGGCCCAGCCTAACTGCCCAGTGGCTTCCAGATGTAACCAGACCAGAAGGGAAAGATTTC AGCATTCATCGACTTGTCCTGGGGACACACACATCGGATGAACAAAACCATCTTGTTATA GCCAGTGTGCAGCTCCCTAATGATGATGCTCAGTTTGATGCGTCACACTACGACAGTGAG AAAGGAGAATTTGGAGGTTTTGGTTCAGTTAGTGGAAAAATTGAAATAGAAATCAAGATC AACCATGAAGGAGAAGTAAACAGGGCCCGTTATATGCCCCAGAACCCTTGTATCATCGCA ACAAAGACTCCTTCCAGTGATGTTCTTGTTTTTGACTATACAAAACATCCTTCTAAACCA GATCCTTCTGGAGAGTGCAACCCAGACTTGCGTCTCCGTGGACATCAGAAGGAAGGCTAT GGGCTTTCTTGGAACCCAAATCTCAGTGGGCACTTACTTAGTGCTTCAGATGACCATACC ATCTGCCTGTGGGACATCAGTGCCGTTCCAAAGGAGGGAAAAGTGGTAGATGCGAAGACC ATCTTTACAGGGCATACGGCAGTAGTAGAAGATGTTTCCTGGCATCTACTCCATGAGTCT CTGTTTGGGTCAGTTGCTGATGATCAGAAACTTATGATTTGGGATACTCGTTCAAACAAT ACTTCCAAACCAAGCCACTCAGTTGATGCTCACACTGCTGAAGTGAACTGCCTTTCTTTC AATCCTTATAGTGAGTTCATTCTTGCCACAGGATCAGCTGACAAGACTGTTGCCTTGTGG GATCTGAGAAATCTGAAACTTAAGTTGCATTCCTTTGAGTCACATAAGGATGAAATATTC CAGGTTCAGTGGTCACCTCACAATGAGACTATTTTAGCTTCCAGTGGTACTGATCGCAGA CTGAATGTCTGGGATTTAAGTAAAATTGGAGAGGAACAATCCCCAGAAGATGCAGAAGAC GGGCCACCAGAGTTGTTGTTTATTCATGGTGGTCATACTGCCAAGATATCTGATTTCTCC TGGAATCCCAATGAACCTTGGGTGATTTGTTCTGTATCAGAAGACAATATCATGCAAGTG TGGCAAATGGCAGAGAACATTTATAATGATGAAGACCCTGAAGGAAGCGTGGATCCAGAA GGACAAGGGTCC |
Restriction Sites | Please inquire |
ACCN | NM_001135255 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001135255.1, NP_001128727.1 |
RefSeq Size | 7940 bp |
RefSeq ORF | 1275 bp |
Locus ID | 5928 |
UniProt ID | Q09028 |
Protein Families | Druggable Genome, Transcription Factors |
Gene Summary | This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] Transcript Variant: This variant (2) uses an alternate in-frame splice site compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is one aa shorter compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC225685 | RBBP4 (Myc-DDK-tagged)-Human retinoblastoma binding protein 4 (RBBP4), transcript variant 2 |
CNY 3,990.00 |
|
RC225685L3 | Lenti-ORF clone of RBBP4 (Myc-DDK-tagged)-Human retinoblastoma binding protein 4 (RBBP4), transcript variant 2 |
CNY 5,890.00 |
|
RC225685L4 | Lenti-ORF clone of RBBP4 (mGFP-tagged)-Human retinoblastoma binding protein 4 (RBBP4), transcript variant 2 |
CNY 5,890.00 |
|
RG225685 | RBBP4 (tGFP-tagged) - Human retinoblastoma binding protein 4 (RBBP4), transcript variant 2 |
CNY 4,370.00 |