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IL18BP (NM_173042) Human Untagged Clone
CAT＃: SC324219
IL18BP (untagged)-Human interleukin 18 binding protein (IL18BP), transcript variant A
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FVH; IL18BPa |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_173042.2
CACGCAGCTAGACACAGCTAACTTGAGTCTTGGAGCTCCTAGAGGGAAGCTTCTGGAAAG
GAAGGCTCTTCAGGACCTCTTAGGAGCCAGTGTGAAGGTGAAGGAGGAAGCAGATGCCTG TTCATATGGAAACAAAGACCTGGCTGTGAAGAGGGGAGGCGGACACCAAAGTCCTGACAC TTGGGCGGGACAGAATTGATCTAGAAGAGGACGTTGTCACAGATAAAGAGCCAGGCTCAC CAGCTCCTGACGCATGCATCATGACCATGAGACACAACTGGACACCAGACCTCAGCCCTT TGTGGGTCCTGCTCCTGTGTGCCCACGTCGTCACTCTCCTGGTCAGAGCCACACCTGTCT CGCAGACCACCACAGCTGCCACTGCCTCAGTTAGAAGCACAAAGGACCCCTGCCCCTCCC AGCCCCCAGTGTTCCCAGCAGCTAAGCAGTGTCCAGCATTGGAAGTGACCTGGCCAGAGG TGGAAGTGCCACTGAATGGAACGCTGAGCTTATCCTGTGTGGCCTGCAGCCGCTTCCCCA ACTTCAGCATCCTCTACTGGCTGGGCAATGGTTCCTTCATTGAGCACCTCCCAGGCCGAC TGTGGGAGGGGAGCACCAGCCGGGAACGTGGGAGCACAGGTACGCAGCTGTGCAAGGCCT TGGTGCTGGAGCAGCTGACCCCTGCCCTGCACAGCACCAACTTCTCCTGTGTGCTCGTGG ACCCTGAACAGGTTGTCCAGCGTCACGTCGTCCTGGCCCAGCTCTGGGCTGGGCTGAGGG CAACCTTGCCCCCCACCCAAGAAGCCCTGCCCTCCAGCCACAGCAGTCCACAGCAGCAGG GTTAAGACTCAGCACAGGGCCAGCAGCAGCACAACCTTGACCAGAGCTTGGGTCCTACCT GTCTACCTGGAGTGAACAGTCCCTGACTGCCTGTAGGCTGCGTGGATGCGCAACACACCC CCTCCTTCTCTGCTTTGGGTCCCTTCTCTCACCAAATTCAAACTCCATTCCCACCTACCT AGAAAATCACAGCCTCCTTATAATGCCTCCTCCTCCTGCCATTCTCTCTCCACCTATCCA TTAGCCTTCCTAACGTCCTACTCCTCACACTGCTCTACTGCTCAGAAACCACCAAGACTG TTGATGCCTTAGCCTTGCACTCCAGGGCCCTACCTGCATTTCCCACATGACTTTCTGGAA GCCTCCCAACTATTCTTGCTTTTCCCAGACAGCTCCCACTCCCATGTCTCTGCTCATTTA GTCCCGTCTTCCTCACCGCCCCAGCAGGGGAACGCTCAAGCCTGGTTGAAATGCTGCCTC TTCAGTGAAGTCATCCTCTTTCAGCTCTGGCCGCATTCTGCAGACTTCCTATCTTCGTGC TGTATGTTTTTTTTTTTCCCCCTTCACTCTAATGGACTGTTCCAGGGAAGGGATGGGGGC AGCAGCTGCTTCGGATCCACACTGTATCTGTGTCATCCCCACATGGGTCCTCATAAAGGA TTATTCAATGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAA |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_173042 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_173042.2, NP_766630.2 |
| RefSeq Size | 2189 bp |
| RefSeq ORF | 585 bp |
| Locus ID | 10068 |
| UniProt ID | O95998 |
| Protein Families | Druggable Genome, Secreted Protein |
| Gene Summary | The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011] Transcript Variant: This variant (A) encodes the predominant isoform (a, also known as IL-18BPa), which shows the highest affinity for binding IL-18 (PMID:10655506). Variants A, E, F and G encode the same isoform. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208111 | IL18BP (Myc-DDK-tagged)-Human interleukin 18 binding protein (IL18BP), transcript variant A |
CNY 2,400.00 |
|
| RC208111L3 | Lenti ORF clone of Human interleukin 18 binding protein (IL18BP), transcript variant A, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208111L4 | Lenti ORF clone of Human interleukin 18 binding protein (IL18BP), transcript variant A, mGFP tagged |
CNY 5,890.00 |
|
| RG208111 | IL18BP (tGFP-tagged) - Human interleukin 18 binding protein (IL18BP), transcript variant A |
CNY 4,000.00 |
|
| SC110117 | IL18BP (untagged)-Human interleukin 18 binding protein (IL18BP), transcript variant A |
CNY 2,400.00 |
