IL18BP (NM_173042) Human Untagged Clone

CAT#: SC110117

IL18BP (untagged)-Human interleukin 18 binding protein (IL18BP), transcript variant A



  "NM_173042" in other vectors (5)

CNY 2,400.00

CNY 2,950.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
Anti-IL18BP Rabbit Polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms FVH; IL18BPa
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC110117 sequence for NM_173042 edited (data generated by NextGen Sequencing)
ATGACCATGAGACACAACTGGACACCAGACCTCAGCCCTTTGTGGGTCCTGCTCCTGTGT
GCCCACGTCGTCACTCTCCTGGTCAGAGCCACACCTGTCTCGCAGACCACCACAGCTGCC
ACTGCCTCAGTTAGAAGCACAAAGGACCCCTGCCCCTCCCAGCCCCCAGTGTTCCCAGCA
GCTAAGCAGTGTCCAGCATTGGAAGTGACCTGGCCAGAGGTGGAAGTGCCACTGAATGGA
ACGCTGAGCTTATCCTGTGTGGCCTGCAGCCGCTTCCCCAACTTCAGCATCCTCTACTGG
CTGGGCAATGGTTCCTTCATTGAGCACCTCCCAGGCCGACTGTGGGAGGGGAGCACCAGC
CGGGAACGTGGGAGCACAGGTACGCAGCTGTGCAAGGCCTTGGTGCTGGAGCAGCTGACC
CCTGCCCTGCACAGCACCAACTTCTCCTGTGTGCTCGTGGACCCTGAACAGGTTGTCCAG
CGTCACGTCGTCCTGGCCCAGCTCTGGGCTGGGCTGAGGGCAACCTTGCCCCCCACCCAA
GAAGCCCTGCCCTCCAGCCACAGCAGTCCACAGCAGCAGGGTTAA

Clone variation with respect to NM_173042.2
>OriGene 5' read for NM_173042 unedited
NNGGGGTCACATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGTGAAAG
TGAAATAGAGGGTCGGGGCAGTGCTTTCCCAGAAGGATTGCTCGGCATCCTGCCCTTCCC
AGAAGCAGCTCTGGTGCTGAAGAGAGCACTGCCTCCCTGTGTGACTGGGTGAGTCCATAT
TCTCTCTTTGGGTCTCAATTTTGCCTTCCCTAATGAAGGGGTAAGATTGGACTAGGTAAG
CATCTTACAACCATTTGTGGTCATGAGAGCTGGGGTGGGGAAGGATTGTCACTTGACCCC
CCCAGCTCTGTTTCTAAGTGCTGAAAGAGCTCCAGGCTATGCTACGGGAGGAGAAGCCAG
CTACTGAGGAAAAGCCAGCTACTGAGAAAAAGCGGGAGTGGTTTACCATTCTCCTCCCCC
ACCTTTCACCAGAGAAGAGGACGTTGTCACAGATAAAGAGCCAGGCTCACCAGCTCCTGA
CGCATGCATCATGACCATGAGACACAACTGGACACCAGACCTCAGCCCTTTGTGGGTCCT
GCTCCTGTGTGCCCACGTCGTCACTCTCCTGGTCAGAGCCACACCTGTCTCGCAGACCAC
CACAGCTGCCACTGCCTCAGTTAGAAGCACAAAGGACCCCTGCCCCTCCCAGCCCCCAGT
GTTCCCAGCAGCTAAGCAGTGTCCAGCATTGGAAGTGACCTGGCCAGAGGTGGAAGTGCC
ACTGAATGGAACGCTGAGCTTATCCTGTGTGGCCTGCAGCCGCTTCCCAACTTCACATCC
TCTACTGGCTGGGCAATGGTTCCTTCATTGAGCCCTCCAGCGACGGTGGGGGGAGGGGAG
CACCACCGGGAACGTGGGAGCACAGTACGCAGCTGTGCAGGNCCTTNGTGCTGNAGCAGC
TGACCCC
Restriction Sites ECoRI-NOT     
ACCN NM_173042
Insert Size 2000 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_173042.1, NP_766630.1
RefSeq Size 3399 bp
RefSeq ORF 579 bp
Locus ID 10068
UniProt ID O95998
Protein Families Druggable Genome, Secreted Protein
Gene Summary The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
Transcript Variant: This variant (A) encodes the predominant isoform (a, also known as IL-18BPa), which shows the highest affinity for binding IL-18 (PMID:10655506). Variants A, E, F and G encode the same isoform.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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