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Thymine DNA glycosylase (TDG) (NM_003211) Human Untagged Clone
CAT＃: SC324192
TDG (untagged)-Human thymine-DNA glycosylase (TDG)
CNY 3,656.00
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | hTDG |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_003211.3
GGGGGACAGTAGAAGCCTGGAGGAGGAGCTTGAGTCCAGCCACTGTCTGGGTACTGCCAG
CCATCGGGCCCAGGTCTCTGGGGTTGTCTTACCGCAGTGAGTACCACGCGGTACTACAGA GACCGGCTGCCCGTGTGCCCGGCAGGTGGAGCCGCCCGCATCAGCGGCCTCGGGGAATGG AAGCGGAGAACGCGGGCAGCTATTCCCTTCAGCAAGCTCAAGCTTTTTATACGTTTCCAT TTCAACAACTGATGGCTGAAGCTCCTAATATGGCAGTTGTGAATGAACAGCAAATGCCAG AAGAAGTTCCAGCCCCAGCTCCTGCTCAGGAACCAGTGCAAGAGGCTCCAAAAGGAAGAA AAAGAAAACCCAGAACAACAGAACCAAAACAACCAGTGGAACCCAAAAAACCTGTTGAGT CAAAAAAATCTGGCAAGTCTGCAAAATCAAAAGAAAAACAAGAAAAAATTACAGACACAT TTAAAGTAAAAAGAAAAGTAGACCGTTTTAATGGTGTTTCAGAAGCTGAACTTCTGACCA AGACTCTCCCCGATATTTTGACCTTCAATCTGGACATTGTCATTATTGGCATAAACCCGG GACTAATGGCTGCTTACAAAGGGCATCATTACCCTGGACCTGGAAACCATTTTTGGAAGT GTTTGTTTATGTCAGGGCTCAGTGAGGTCCAGCTGAACCATATGGATGATCACACTCTAC CAGGGAAGTATGGTATTGGATTTACCAACATGGTGGAAAGGACCACGCCCGGCAGCAAAG ATCTCTCCAGTAAAGAATTTCGTGAAGGAGGACGTATTCTAGTACAGAAATTACAGAAAT ATCAGCCACGAATAGCAGTGTTTAATGGAAAATGTATTTATGAAATTTTTAGTAAAGAAG TTTTTGGAGTAAAGGTTAAGAACTTGGAATTTGGGCTTCAGCCCCATAAGATTCCAGACA CAGAAACTCTCTGCTATGGTATGCCATCATCCAGTGCAAGATGTGCTCAGTTTCCTCGAG CCCAAGACAAAGTTCATTACTACATAAAACTGAAGGACTTAAGAGATCAGTTGAAAGGCA TTGAACGAAATATGGACGTTCAAGAGGTGCAATATACATTTGACCTACAGCTTGCCCAAG AGGATGCAAAGAAGATGGCTGTTAAGGAAGAAAAATATGATCCAGGTTATGAGGCAGCAT ATGGTGGTGCTTACGGAGAAAATCCATGCAGCAGTGAACCTTGTGGCTTCTCTTCAAATG GGCTAATTGAGAGCGTGGAGTTAAGAGGAGAATCAGCTTTCAGTGGCATTCCTAATGGGC AGTGGATGACCCAGTCATTTACAGACCAAATTCCTTCCTTTAGTAATCACTGTGGAACAC AAGAACAGGAAGAAGAAAGCCATGCTTAAGAATGGTGCTTCTCAGCTCTGCTTAAATGCT GCAGTTTTAATGCAGTTGTCAACAAGTAGAACCTCAGTTTGCTAACTGAAGTGTTTTATT AGTATTTTACTCTAGTGGTGTAATTGTAATGTAGAACAGTTGTGTGGTAGTGTGAACCGT ATGAACCTAAGTAGTTTGGAAGAAAAAGTAGGGTTTTTGTATACTAGCTTTTGTATTTGA ATTAATTATCATTCCAGCTTTTTATATACTATATTTCATTTATGAAGAAATTGATTTTCT TTTGGGAGTCACTTTTAATCTGTAATTTTAAAATACAAGTCTGAATATTTATAGTTGATT CTTAACTGTGCATAAACCTAGATATACCATTATCCCTTTTATACCTAAGAAGGGCATGCT AATAATTACCACTGTCAAAGAGGCAAAGGTGTTGATTTTTGTATATGAAGTTAAGCCTCA GTGGAGTCTCATTTGTTAGTTTTTAGTGGTAACTAAGGGTAAACTCAGGGTTCCCTGAGC TATATGCACACTCAGACCTCTTTGCTTTACCAGTGGTGTTTGTGAGTTGCTCAGTAGTAA AAACTGGCCTTACCTGACAGAGCCCTGGCTTTGACCTGCTCAGCCCTGTGTGTTAATCCT CTAGTAGCCAATTAACTACTCTGGGGTGGCAGGTTCCAGAGAATGCAGTAGACCTTTTGC CACTCATCTGTGTTTTACTTGAGACATGTAAATATGATAGGGAAGGAACTGAATTTCTCC ATTCATATTTATAACCATTCTAGTTTTATCTTCCTTGGCTTTAAGAGTGTGCCATGGAAA GTGATAAGAAATGAACTTCTAGGCTAAGCAAAAAGATGCTGGAGATATTTGATACTCTCA TTTAAACTGGTGCTTTATGTACATGAGATGTACTAAAATAAGTAATATAGAATTTTTCTT GCTAGGTAAATCCAGTAAGCCAATAATTTTAAAGATTCTTTATCTGCATCATTGCTGTTT GTTACTATAAATTAAATGAACCTCATGGAAAGGTTGAGGTGTATACCTTTGTGATTTTCT AATGAGTTTTCCATGGTGCTACAAATAATCCAGACTACCAGGTCTGGTAGATATTAAAGC TGGGTACTAAGAAATGTTATTTGCATCCTCTCAGTTACTCCTGAATATTCTGATTTCATA CGTACCCAGGGAGCATGCTGTTTTGTCAATCAATATAAAATATTTATGAGGTCTCCCCCA CCCCCAGGAGGTTATATGATTGCTCTTCTCTTTATAATAAGAGAAACAAATTCTTATTGT GAATCTTAACATGCTTTTTAGCTGTGGCTATGATGGATTTTATTTTTTCCTAGGTCAAGC TGTGTAAAAGTCATTTATGTTATTTAAATGATGTACTGTACTGCTGTTTACATGGACGTT TTGTGCGGGTGCTTTGAAGTGCCTTGCATCAGGGATTAGGAGCAATTAAATTATTTTTTC ACGGGACTGTGTAAAGCATGTAACTAGGTATTGCTTTGGTATATAACTATTGTAGCTTTA CAAGAGATTGTTTTATTTGAATGGGGAAAATACCCTTTAAATTATGACGGACATCCACTA GAGATGGGTTTGAGGATTTTCCAAGCGTGTAATAATGATGTTTTTCCTAACATGACAGAT GAGTAGTAAATGTTGATATATCCTATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_003211 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003211.3, NP_003202.3 |
| RefSeq Size | 3229 bp |
| RefSeq ORF | 1233 bp |
| Locus ID | 6996 |
| UniProt ID | Q13569 |
| Domains | UDG |
| Protein Families | Druggable Genome |
| Protein Pathways | Base excision repair |
| Gene Summary | The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207113 | TDG (Myc-DDK-tagged)-Human thymine-DNA glycosylase (TDG) |
CNY 3,656.00 |
|
| RC207113L1 | Lenti ORF clone of Human thymine-DNA glycosylase (TDG), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC207113L2 | Lenti ORF clone of Human thymine-DNA glycosylase (TDG), mGFP tagged |
CNY 5,890.00 |
|
| RC207113L3 | Lenti ORF clone of Human thymine-DNA glycosylase (TDG), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC207113L4 | Lenti ORF clone of Human thymine-DNA glycosylase (TDG), mGFP tagged |
CNY 6,056.00 |
|
| RG207113 | TDG (tGFP-tagged) - Human thymine-DNA glycosylase (TDG) |
CNY 5,256.00 |
|
| SC118135 | TDG (untagged)-Human thymine-DNA glycosylase (TDG) |
CNY 3,656.00 |
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