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ITM2C (NM_001012514) Human Untagged Clone
CAT＃: SC323848
ITM2C (untagged)-Human integral membrane protein 2C (ITM2C), transcript variant 3
CNY 2,400.00
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BRI3; BRICD2C; E25; E25C; ITM3 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_001012514.1
GGCGGAGGCAGAGACCGAGGCTGCACCGGCAGAGGCTGCGGGGCGGACGCGCGGGCCGGC
GCAGCCATGGTGAAGATTAGCTTCCAGCCCGCCGTGGCTGGCATCAAGGGCGACAAGGCT GACAAGGCGTCGGCGTCGGCCCCTGCGCCGGCCTCGGCCACCGAGATCCTGCTGACGCCG GCTAGGCTGGCCCGAGATAACTTCTTCCGCTGTGGTGTGCTGTATGAGGACTCCCTGTCC TCCCAGGTCCGGACTCAGATGGAGCTGGAAGAGGATGTGAAAATCTACCTCGACGAGAAC TACGAGCGCATCAACGTGCCTGTGCCCCAGTTTGGCGGCGGTGACCCTGCAGACATCATC CATGACTTCCAGCGGGGTCTGACTGCGTACCATGATATCTCCCTGGACAAGTGCTATGTC ATCGAACTCAACACCACCATTGTGCTGCCCCCTCGCAACTTCTGGGAGCTCCTCATGAAC GTGAAGAGGGGGACCTACCTGCCGCAGACGTACATCATCCAGGAGGAGATGGTGGTCACG GAGCATGTCAGTGACAAGGAGGCCCTGGGGTCCTTCATCTACCACCTGTGCAACGGGAAA GACACCTACCGGCTCCGGCGCCGGGCAACGCGGAGGCGGATCAACAAGCGTGGGGCCAAG AACTGCAATGCCATCCGCCACTTCGAGAACACCTTCGTGGTGGAGACGCTCATCTGCGGG GTGGTGTGAGGCCCTCCTCCCCCAGAACCCCCTGCCGTGTTCCTCTTTTCTTCTTTCCGG CTGCTCTCTGGCCCTCCTCCTTCCCCCTGCTTAGCTTGTACTTTGGACGCGTTTCTATAG AGGTGACATGTCTCTCCATTCCTCTCCAACCCTGCCCACCTCCCTGTACCAGAGCTGTGA TCTCTCGGTGGGGGGCCCATCTCTGCTGACCTGGGTGTGGCGGAGGGAGAGGCGATGCTG CAAAGTGTTTTCTGTGTCCCACTGTCTTGAAGCTGGGCCTGCCAAAGCCTGGGCCCACAG CTGCACCGGCAGCCCAAGGGGAAGGACCGGTTGGGGGAGCCGGGCATGTGAGGCCCTGGG CAAGGGGATGGGGCTGTGGGGGCGGGGCGGCATGGGCTTCAGAAGTATCTGCACAATTAG AAAAGTCCTCAGAAGCTTTTTCTTGGAGGGTACACTTTCTTCACTGTCCCTATTCCTAGA CCTGGGGCTTGAGCTGAGGATGGGACGATGTGCCCAGGGAGGGACCCACCACAGCACAAG AGAAGGTGGCTACCTGGGGGTGTCCCAGGGACTCTGTCAGTGCCTTCAGCCCACCAGCAG GAGCTTGGAGTTTGGGGAGTGGGGATGAGTCCGTCAAGCACAACTGTTCTCTGAGTGGAA CCAAAGAAGCAAGGAGCTAGGACCCCCAGTCCTGCCCCCCAGGAGCACAAGCAGGGTCCC CTCAGTCAAGGCAGTGGGATGGGCGGCTGAGAACGGGGCAGGCAAGGTCACTGCTCAGTC ACGTCCACGGGGGACGAGCCGTGGGTTCTGCTGAGTAGGTGGAGCTCATTGCTTTCTCCA AGCTTGGAACTGTTTTGAAAGATAACACAGAGGGAAAGGGAGAGCCACCTGGTACTTGTC CACCCTGCCTCCTCTGTTCTGAAATTCCATCCCCCTCAGCTTAGGGGAATGCACCTTTTT CCCTTTCCTTCTCACTTTTGCATGTTTTTACTGATCATTCGATATGCTAACCGTTCTCAG CCCTGAGCCTTGGAGAGGAGGGCTGTAACGCCTTCAGTCAGTCTCTGGGGATGAAACTCT TAAATGCTTTGTATATTTTCTCAATTAGATCTCTTTTCAGAAGTGTCTATAGAACAATAA AAATCTTTTACTTCTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAA |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_001012514 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001012514.1, NP_001012532.1 |
| RefSeq Size | 1982 bp |
| RefSeq ORF | 663 bp |
| Locus ID | 81618 |
| UniProt ID | Q9NQX7 |
| Protein Families | Transmembrane |
| Gene Summary | Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (3) is shorter, compared to isoform 1. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208687 | ITM2C (Myc-DDK-tagged)-Human integral membrane protein 2C (ITM2C), transcript variant 3 |
CNY 2,400.00 |
|
| RC208687L3 | Lenti ORF clone of Human integral membrane protein 2C (ITM2C), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208687L4 | Lenti ORF clone of Human integral membrane protein 2C (ITM2C), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RG208687 | ITM2C (tGFP-tagged) - Human integral membrane protein 2C (ITM2C), transcript variant 3 |
CNY 4,000.00 |
