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ARS2 (SRRT) (NM_001128853) Human Untagged Clone
CAT＃: SC323225
SRRT (untagged)-Human serrate RNA effector molecule homolog (Arabidopsis) (SRRT), transcript variant 4
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARS2; ASR2; serrate |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001128853, the custom clone sequence may differ by one or more nucleotides
ATGGGTGACAGTGATGACGAGTACGATCGAAGGCGCAGGGACAAGTTCAGAAGAGAGCGC AGCGACTACGACCGTTCCCGCGAGAGAGATGAAAGACGTCGAGGGGACGATTGGAATGAC AGAGAGTGGGACCGTGGCCGTGAGCGCCGTAGTCGGGGTGAATATCGGGACTATGACCGG AATCGGCGAGAGCGCTTCTCGCCACCTCGCCACGAACTCAGCCCGCCACAGAAGCGCATG AGGAGAGACTGGGATGAGCACAGCTCTGACCCATACCACAGTGGCTATGAGATGCCCTAT GCTGGGGGGGGTGGGGGCCCAACTTATGGCCCCCCTCAGCCCTGGGGCCACCCTGACGTC CACATCATGCAGCACCATGTCCTGCCTATCCAGGCCAGGCTGGGCAGCATTGCAGAGATT GACCTGGGTGTGCCGCCGCCCGTGATGAAGACCTTCAAGGAGTTTCTCCTCTCCCTGGAT GACTCGGTGGATGAGACGGAGGCCGTCAAGCGCTATAATGACTACAAGCTGGATTTCCGG AGGCAACAGATGCAGGATTTCTTCCTGGCGCACAAAGATGAGGAGTGGTTTCGGTCTAAG TACCACCCAGATGAGGTGGGGAAGCGTCGGCAGGAGGCCCGGGGGGCCCTGCAAAACCGA CTGAGGGTCTTCCTGTCCCTCATGGAGACTGGCTGGTTTGATAACCTTCTCCTGGACATA GACAAAGCTGATGCCATTGTCAAGATGCTGGATGCAGCCGTGATTAAGATGGAAGGAGGC ACGGAGAATGATCTTCGCATCCTGGAGCAGGAGGAGGAGGAGGAGCAGGCAGGAAAGCCT GGGGAGCCCAGCAAGAAAGAAGAAGGACGGGCTGGAGCAGGCCTAGGGGACGGGGAGCGC AAAACCAACGACAAGGATGAGAAGAAGGAAGACGGCAAGCAGGCTGAGAATGACAGTTCT AATGATGACAAAACAAAGAAGTCGGAGGGTGATGGGGACAAGGAAGAGAAGAAAGAAGAC TCCGAGAAGGAAGCCAAAAAGAGTAGCAAGAAGCGGAACCGGAAGCACAGTGGTGACGAC AGCTTTGACGAGGGCAGCGTGTCAGAGTCTGAGTCGGAGTCAGAGAGCGGCCAGGCTGAG GAGGAGAAGGAGGAGGCCGAAGAAGCGCTCAAGGAGAAGGAGAAGCCCAAGGAAGAAGAA TGGGAGAAGCCCAAGGACGCCGCGGGGCTGGAGTGCAAGCCGCGGCCGCTGCATAAGACC TGCTCCCTCTTCATGCGCAACATCGCGCCCAACATCTCCCGGGCCGAGATCATCTCCCTT TGTAAAAGGTACCCAGGCTTTATGCGGGTGGCGCTCTCAGAGCCCCAGCCAGAGAGGAGG TTTTTCCGTCGTGGCTGGGTGACCTTCGACCGCAGTGTTAACATTAAAGAGATCTGTTGG AACCTGCAGAACATCCGTCTCCGGGAGTGTGAGCTGAGCCCTGGTGTGAACAGGGACCTG ACCCGGCGCGTTCGCAACATCAACGGCATCACCCAGCACAAGCAGATTGTGCGCAACGAC ATCAAGCTGGCGGCCAAGCTGATCCACACGCTGGATGACAGGACACAGCTTTGGGCCTCA GAACCAGGGACGCCTCCCCTGCCCACGAGCCTGCCCTCGCAAAACCCGATCTTGAAGAAT ATCACCGACTACCTGATCGAGGAAGTAAGCGCCGAGGAGGAGGAGCTGCTGGGGAGCAGC GGGGGCGCTCCTCCTGAGGAGCCTCCTAAGGAAGGGAACCCGGCAGAGATCAACGTGGAG CGGGATGAGAAGTTGATTAAGGTCTTGGACAAGCTCCTCCTTTACCTGCGCATCGTGCAT TCCTTGGATTATTACAACACCTGTGAGTACCCCAACGAGGACGAGATGCCCAATCGCTGT GGGATCATCCACGTTCGGGGGCCCATGCCACCCAACCGCATCAGTCACGGGGAAGTGCTG GAGTGGCAGAAGACTTTTGAGGAGAAGCTCACGCCGTTGCTGAGTGTGCGGGAGTCACTC TCAGAGGAAGAGGCCCAGAAGATGGGGCGCAAAGACCCAGAGCAGGAAGTGGAGAAGTTC GTCACCTCCAACACGCAGGAACTGGGCAAGGATAAGTGGCTGTGTCCTCTCAGTGGCAAG AAATTCAAGGGTCCTGAGTTTGTGCGCAAACATATCTTCAACAAGCATGCAGAGAAAATT GAGGAAGTGAAAAAGGAAGTCGCGTTTTTTAACAACTTCCTCACTGATGCTAAGCGCCCA GCTCTGCCTGAGATCAAGCCAGCCCAGCCACCTGGCCCCGCCCAGAGTTTGACCCCAGGA CTCCCCTACCCACACCAGACTCCCCAGGGCCTGATGCCCTATGGTCAGCCCCGGCCCCCG ATCTTGGGCTATGGAGCTGGTGCTGTCCGCCCTGCAGTCCCCACAGGAGGCCCTCCATAC CCCCATGCCCCGTATGGTGCTGGTCGAGGGAACTATGATGCCTTCCGAGGCCAGGGAGGT TATCCTGGGAAACCTCGCAACAGGATGGTTCGTGGAGACCCAAGGGCCATTGTGGAATAT CGGGACCTGGATGCCCCAGACGATGTTGATTTCTTT |
| Restriction Sites | Please inquire |
| ACCN | NM_001128853 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001128853.1, NP_001122325.1 |
| RefSeq Size | 3020 bp |
| RefSeq ORF | 2619 bp |
| Locus ID | 51593 |
| UniProt ID | Q9BXP5 |
| Gene Summary | Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (4) uses an alternate in-frame splice junction at the end of a 3' exon compared to variant 1. The resulting isoform (d) has the same N- and C-termini but is 4 aa shorter compared to isoform a. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC226228 | SRRT (Myc-DDK-tagged)-Human serrate RNA effector molecule homolog (Arabidopsis) (SRRT), transcript variant 4 |
CNY 7,130.00 |
|
| RC226228L3 | Lenti-ORF clone of SRRT (Myc-DDK-tagged)-Human serrate RNA effector molecule homolog (Arabidopsis) (SRRT), transcript variant 4 |
CNY 9,030.00 |
|
| RC226228L4 | Lenti-ORF clone of SRRT (mGFP-tagged)-Human serrate RNA effector molecule homolog (Arabidopsis) (SRRT), transcript variant 4 |
CNY 9,030.00 |
|
| RG226228 | SRRT (tGFP-tagged) - Human serrate RNA effector molecule homolog (Arabidopsis) (SRRT), transcript variant 4 |
CNY 7,890.00 |
