CYP2C18 (NM_001128925) Human Untagged Clone
CAT#: SC323062
CYP2C18 (untagged)-Human cytochrome P450, family 2, subfamily C, polypeptide 18 (CYP2C18), transcript variant 2
CNY 7,220.00
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CPCI; CYP2C; CYP2C17; P450-6B/29C; P450IIC17 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>SC323062 representing NM_001128925.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGATCCAGCTGTGGCTCTGGTGCTCTGTCTCTCCTGTTTGTTTCTCCTTTCACTCTGGAGGCAGAGC TCTGGAAGAGGGAGGCTCCCGTCTGGCCCCACTCCTCTCCCGATTATTGGAAATATCCTGCAGTTAGAT GTTAAGGACATGAGCAAATCCTTAACCAATTTCTCAAAAGTCTATGGCCCTGTGTTCACTGTGTATTTT GGCCTGAAGCCCATTGTGGTGTTGCATGGATATGAAGCAGTGAAGGAGGCCCTGATTGATCATGGAGAG GAGTTTTCTGGAAGAGGAAGTTTTCCAGTGGCTGAAAAAGTTAACAAAGGACTTGGAATCCTTTTCAGC AATGGAAAGAGATGGAAGGAGATCCGGCGTTTCTGCCTCATGACTCTGCGGAATTTTGGGATGGGGAAG AGGAGCATCGAGGACCGTGTTCAAGAGGAAGCCCGCTGCCTTGTGGAGGAGTTGAGAAAAACCAATGCC TCACCCTGTGATCCCACTTTCATCCTGGGCTGTGCTCCCTGCAATGTGATCTGCTCTGTTATTTTCCAT GATCGATTTGATTATAAAGATCAGAGGTTTCTTAACTTGATGGAAAAATTCAATGAAAACCTCAGGATT CTGAGCTCTCCATGGATCCAGGAAAAGCACAATCAACAGTCTGAATTTACTGTTGAAAGCTTGATAGCC ACTGTAACTGATATGTTTGGGGCTGGAACAGAGACAACGAGCACCACTCTGAGATATGGACTCCTGCTC CTGCTGAAGTACCCAGAGGTCACAGCTAAAGTCCAGGAAGAGATTGAATGTGTAGTTGGCAGAAACCGG AGCCCCTGTATGCAGGACAGGAGTCACATGCCCTACACAGATGCTGTGGTGCACGAGATCCAGAGATAC ATTGACCTCCTCCCCACCAACCTGCCCCATGCAGTGACCTGTGATGTTAAATTCAAAAACTACCTCATC CCCAAGGGCACGACCATAATAACATCCCTGACTTCTGTGCTGCACAATGACAAAGAATTCCCCAACCCA GAGATGTTTGACCCTGGCCACTTTCTGGATAAGAGTGGCAACTTTAAGAAAAGTGACTACTTCATGCCT TTCTCAGCAGGAAAACGGATGTGTATGGGAGAGGGCCTGGCCCGCATGGAGCTGTTTTTATTCCTGACC ACCATTTTGCAGAACTTTAACCTGAAATCTCAGGTTGACCCAAAGGATATTGACATCACCCCCATTGCC AATGCATTTGGTCGTGTGCCACCCTTGTACCAGCTCTGCTTCATTCCTGTCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
Restriction Sites | SgfI-MluI |
ACCN | NM_001128925 |
Insert Size | 1296 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001128925.1 |
RefSeq Size | 2385 bp |
RefSeq ORF | 1296 bp |
Locus ID | 1562 |
UniProt ID | P33260 |
Protein Families | Druggable Genome, P450 |
Protein Pathways | Arachidonic acid metabolism, Drug metabolism - cytochrome P450, Linoleic acid metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism |
MW | 48.8 kDa |
Gene Summary | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks a coding exon in the middle region, but the reading frame is not affected, as compared to variant 1. The resulting isoform (2) lacks an internal segment, as compared to isoform 1. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC225708 | CYP2C18 (Myc-DDK-tagged)-Human cytochrome P450, family 2, subfamily C, polypeptide 18 (CYP2C18), transcript variant 2 |
CNY 3,656.00 |
|
RC225708L3 | Lenti-ORF clone of CYP2C18 (Myc-DDK-tagged)-Human cytochrome P450, family 2, subfamily C, polypeptide 18 (CYP2C18), transcript variant 2 |
CNY 5,890.00 |
|
RC225708L4 | Lenti-ORF clone of CYP2C18 (mGFP-tagged)-Human cytochrome P450, family 2, subfamily C, polypeptide 18 (CYP2C18), transcript variant 2 |
CNY 5,890.00 |
|
RG225708 | CYP2C18 (tGFP-tagged) - Human cytochrome P450, family 2, subfamily C, polypeptide 18 (CYP2C18), transcript variant 2 |
CNY 4,370.00 |
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