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DVL1 (NM_182779) Human Untagged Clone
CAT＃: SC322649
DVL1 (untagged)-Human dishevelled, dsh homolog 1 (Drosophila) (DVL1), transcript variant 3
CNY 3,656.00
CNY 8,550.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | dishevelled, dsh homolog 1 (Drosophila); dishevelled 1; dishevelled 1 (homologous to Drosophila dsh); DVL; DVL, MGC54245; MGC54245; OTTHUMP00000003104 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for SC322649
GCGGGTAGCGCCCCGCGTCCGAGCCTCGGGCCGGGCCCTGAGCGCGCGGGCTCCGCGCCG
CCGCCGCGCCATGGCGGAGACCAAGATTATCTACCACATGGACGAGGAGGAGACGCCGTA CCTGGTCAAGCTGCCCGTGGCCCCCGAGCGCGTCACGCTGGCCGACTTCAAGAACGTGCT CAGCAACCGGCCCGTGCACGCCTACAAATTCTTCTTTAAGTCCATGGACCAGGACTTCGG GGTGGTGAAGGAGGAGATCTTTGATGACAATGCCAAGCTTCCCTGCTTCAACGGCCGCGT GGTCTCCTGGCTGGTCCTGGCTGAGGGTGCTCACTCGGATGCGGGGTCCCAGGGCACGGA CAGCCACACAGACCTGCCCCCGCCTCTTGAGCGGACAGGCGGCATCGGGGACTCCCGGCC CCCCTCCTTCCACCCGAATGTGGCCAGCAGCCGTGACGGGATGGACAACGAGACAGGCAC GGAGTCCATGGTCAGTCACCGGCGGGAGCGTGCCCGACGCCGGAACCGCGAGGAGGCCGC CCGGACCAATGGGCACCCAAGGGGAGACCGACGGCGGGATGTGGGGCTGCCCCCAGACAG CGCGTCCACCGCCCTCAGCAGCGAGCTTGAGTCCAGCAGCTTTGTGGACTCGGACGAGGA TGGCAGCACGAGCAGGCTCAGCAGCTCCACGGAGCAGAGCACCTCATCCAGACTCACCCG GAAGTACGCCAGCAGCTTGCTGAAGCACGGCTTCCTGCGGCACACGGTCAACAAGATCAC CTTCTCCGAGCAGTGCTACTACGTCTTCGGGGATCTCTGCAGCAATCTCGCCACCCTGAA CCTCAACAGTGGCTCCAGTGGGACTTCGGATCAGGACACGCTGGCCCCGCTGCCCCACCC GGCTGCCCCCTGGCCTCTGGGTCAGGGCTACCCCTACCAGTACCCGGGACCCCCACCCTG CTTCCCGCCTGCCTACCAGGACCCGGGCTTTAGCTATGGCAGCGGCAGCACCGGGAGTCA GCAGAGTGAAGGGAGCAAAAGCAGTGGGTCCACCCGGAGCAGCCGCCGGGCCCCGGGCCG TGAGAAGGAGCGTCGGGCGGCGGGAGCTGGGGGCAGTGGCAGTGAATCGGATCACACGGC ACCGAGTGGGGTGGGGAGCAGCTGGCGAGAGCGTCCGGCCGGCCAGCTCAGCCGTGGCAG CAGCCCACGCAGTCAGGCCTCGGCTACCGCCCCGGGGCTCCCCCCGCCCCACCCCACGAC CAAGGCCTATACAGTGGTGGGGGGGCCACCCGGGGGACCCCCTGTCCGGGAGCTGGCTGC CGTCCCCCCGGAATTGACAGGCAGCCGCCAGTCCTTCCAGAAGGCTATGGGGAACCCCTG CGAGTTCTTCGTGGACATCATGTGACTCGTGGCGCATGCCCCAGCCCTGCCTGAGGTGGG GAGCTGGCGGTCCTGCCGCATGCAGAGCTCGCGTGGGCTTGCCTTCGTGGGGGCCAGGAC GGGAGGCAGGGTGGGGGGCAGGCTGGACCACCACCATCTGCCCTGGCAGCCTGGCTGCTC CAGCTCCTGACAGCACCTGTGTCTGAGCAGCCGTGTTGGGGGCGCTCCCTCTCTGCCCCT CAGCGAGAGCCTCGGACCTCCCAACCCCTTGTGTCTGGTGGGGATCCCTCCTGGGATGAG GAAGACCCCCTCGGGCTCTCGGCTGACCCCCACCTCCTGCACAGCTGTGCCCAGGCCCCC AGGGTGGTCCACGCGGGGCAACCCCCTGCGGTGCACAGGCCCCCTGTCTGGAGTAGGGAT CTAATTTATTTATTTATTGCCTGGCCGGTGACTCGGGGGAGGAGGCGACCCTGTCATCTG TCCCACCTGCTGCTGCCCCTTGGAGCAGCCTGCACCTTCTCTCCTCCCATCCGGCAACAG TCTGAAAGTACGTGGAGGACGGGACCGGAAGACGAGAGAGGGCTGGACATCCTGCCCACC GTGTCCCAGCCAGGGCAGGGAGGGACCATGGCCCGCAGGGTCAAGGGGCCCCGATGTGCA CAGCTGCCACAGGGAGGGAGGTCTTGGGGAGATGGGCAGTCAGGTGGCCCGTCCTTGGTG AGTGCACACACTGCGCGCACACATCGCGGCCTTCCTGGCTTCTCTGGCCCCCACGTGTCT GTGCTGTAGATACTGTATCAAAGTCCCAGCGTTTAGATGGTTAACATAGAGCTGCTTCTG TGTAAATGCTGCTTATTTTAAACACTAAAAAGCGTTTAATTTTATGGGAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_182779 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_182779.2, NP_877580.1 |
| RefSeq Size | 2286 bp |
| RefSeq ORF | 1335 bp |
| Locus ID | 1855 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
| Protein Pathways | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway |
| Gene Summary | DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) lacks an internal nt segment including several exons in the CDS, as compared to variant 1. The resulting isoform (c) has identical N- and C-termini but lacks an internal aa segment, as compared to isoform a. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Repression of beta-catenin function in malignant cells by nonsteroidal antiinflammatory drugs
,Desheng Lu, Howard B. Cottam, Maripat Corr, and Dennis A. Carson,
Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18567-71
[DVL1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208406 | DVL1 (Myc-DDK-tagged)-Human dishevelled, dsh homolog 1 (Drosophila) (DVL1), transcript variant 3 |
CNY 3,656.00 |
|
| RC208406L3 | Lenti ORF clone of Human dishevelled, dsh homolog 1 (Drosophila) (DVL1), transcript variant 3, Myc-DDK-tagged |
CNY 6,370.00 |
|
| RC208406L4 | Lenti ORF clone of Human dishevelled, dsh homolog 1 (Drosophila) (DVL1), transcript variant 3, mGFP tagged |
CNY 6,370.00 |
|
| RG208406 | DVL1 (tGFP-tagged) - Human dishevelled, dsh homolog 1 (Drosophila) (DVL1), transcript variant 3 |
CNY 4,940.00 |
