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JPT1 (NM_001002033) Human Untagged Clone
CAT＃: SC322083
HN1 (untagged)-Human hematological and neurological expressed 1 (HN1), transcript variant 3
CNY 1,200.00
CNY 3,990.00
Product images
CNY 6,281.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARM2; HN1; HN1A |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for SC322083
CGCGTGCGCTGTGCTCGCGCCGGGGCGGGTGGCGGGGTTCTGCCGTCGGCGCCGCCTTTG
TGCCGCCTGGCGAGCCCTGCGCGCCGGCCCCACCCGGGTCCCTGCTGCTCTCCATTCATT CCTTCCACGGAGTCAGGGGCTGAGGAGGCCGGGGCTGGTCGCCCTTCGGAGCACGGCCGG TTTTCGTTAATCGGAACCTTCGGGGAGGGCTTCGCTTTCTCCTGTGTGCATCCCGGCTGG TGCATCCCCAGGGTGGTGGGCTTGGCCCCCCAGGTGCCCGGGGATCCTTTAGGGCCCCAT GCATGGTCAGGTCCTATTGTCCCATTGATGGGCCACGCGCTCCTGTCTCTCCCCCGTGGC ATGCGGTTGGTCTCGCTCTCGCGCGCAGCCATTGGATCCGGAGACCGGATCGATCAGGTC CGGCGGGCTCCTTACCCTCGCCGTGCCCCCACTCCTTATTCGGACCTACCTGACAGGTGC ATGTGTGGTCGAGCGGGGCTGGTCATCGCGACCCTTCACCCCCCATTGAGGACCCAATCG TTCTTCCCCTCTTCGAAGTGCCTCCCCTCTTCCAAGTGTCTCCCCTTCCTAACAAAGGAA AGACCCCTTCTCCCCATCCCTGCGCTCATTTCTAAGGCGGGGGGCGGGGGCGGGCGCGGG GAACGAGCCAACCCGAGTGGGTTTTCTGCGCTTAAACCTTCGGACCGTGGCCTTTGCATC CTACCTTCGCTTCCTCCTTTGACGTTTGCCCAGTGAGTTCATCCCTGGCCCTGGTTCCCT TGCAGGAGGAGGTTTCTTGTTCTTGGGCGGGGCCGGAGACATCCATTGTCTCTAACGTGG TAGCGCTACCTGGGAAGCGGGGGATTTTTCTTGCCCTTCTTCCCACTGCTTTTTGGGCTT GGGGCACTGGGTACAGTGTTTGGACAGGAACCCTTTTCCAAGTCCTTGCTTAACTTACTT GGTGGAAGGGTTTGGATTCTGTGGAAGGTGTCCACATTGTCTCAGCTAATTGCACACTGT TCTTTAAGAGTTTTGCGGCCTCCAGGTGGTGGATCCAATTTTTCATTAGGTTTTGATGAA CCAACAGAACAACCTGTGAGGAAGAACAAAATGGCCTCTAATATCTTTGGGACACCTGAA GAAAATCAAGCTTCTTGGGCCAAGTCAGCAGGTGCCAAGTCTAGTGGTGGCAGGGAAGAC TTGGAGTCATCTGGACTGCAGAGAAGGAACTCCTCTGAAGCAAGCTCCGGAGACTTCTTA GATCTGAAGGGAGAAGGTGATATTCATGAAAATGTGGACACAGACTTGCCAGGCAGCCTG GGGCAGAGTGAAGAGAAGCCCGTGCCTGCTGCGCCTGTGCCCAGCCCGGTGGCCCCGGCC CCAGTGCCATCCAGAAGAAATCCCCCTGGCGGCAAGTCCAGCCTCGTCTTGGGTTAGCTC TGACTGTCCTGAACGCTGTCGTTCTGTCTGTTTCCTCCATGCTTGTGAACTGCACAACTT GAGCCTGACTGTACATCTCTTGGATTTGTTTCATTAAAAAGAAGCACTTTATGTACTGCT GTCTTTTTTTTTTTTCTTTTGAAGAACAGGTTTCTCTCTGTCCTTGACTCTTGGGTCTGT GGGCCATGGCATGAGTGTTTTCTAGTAGTAGATTGGAGGGAAAGCTTTGTGACACTTAGT ACTGTGTTTTTAAGAAGAAATAATTTGGTTCCAGATGTGTTAGAGGATCTTTTGTACTGA GGTTTTTAACACTTTACTTGGGTTTACCAAGCCTCAACTGGACAGACCATAAACAGTCCA CAGGCACCGTTCCTGCCAGGCCCCAACCCACAGGGAGTCTCTCCGCAGAGCCTTCTTGGT GTTGCCCTAACTTGCCAGTGGCCTTTGCTCAGAGCCTCCTCCTGTGACATGTGAACAATG AAGAGGCCTGCGCCTCCTGCCTTGCCGCCTGCAAAGCAAAGAAACTGCCTTTTATTTTTT AACCTTAAAAAGTAGCCAGATAGTAACAAGACTGGCTGGCTGATGAGCAAAGCCTTTGCT CTCACGCAGAGGAAGGCTTGGATGTACAATGAAACTGCCTGGAACTAAAAGCAGTGAAGC AAGGGAGGCAATCACACTGAAGCGGGTCTTCCTCCAGGAACGGGGTCCCACAGGCGTGTT GTTTTAAATAACCTGATGCTGTGTGCATGATGCTGGTGCTTGACCATGAAAGGAAAGTCT CATCCTTAAAATGTGTTGTACTTCACAATCCTGGACTGTTGCTTCAAGTAAACAATATCC ACATTTCGAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001002033 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001002033.1, NP_001002033.1 |
| RefSeq Size | 1696 bp |
| RefSeq ORF | 327 bp |
| Locus ID | 51155 |
| UniProt ID | Q9UK76 |
| Gene Summary | Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) differs in the 5' UTR and contains multiple coding region differences, one of which results in a frameshift and an early stop codon, compared to variant 2. Variants 3, 5 and 6 encode the same isoform (3), which is shorter and has distinct N- and C-termini, compared to isoform 2. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207344 | HN1 (Myc-DDK-tagged)-Human hematological and neurological expressed 1 (HN1), transcript variant 3 |
CNY 1,200.00 |
|
| RC207344L3 | Lenti ORF clone of Human hematological and neurological expressed 1 (HN1), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207344L4 | Lenti ORF clone of Human hematological and neurological expressed 1 (HN1), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RG207344 | HN1 (tGFP-tagged) - Human hematological and neurological expressed 1 (HN1), transcript variant 3 |
CNY 2,800.00 |
