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SOX9 (NM_000346) Human Untagged Clone
CAT＃: SC321884
SOX9 (untagged)-Human SRY (sex determining region Y)-box 9 (SOX9)
CNY 3,800.00
| Cited in 13 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CMD1; CMPD1; SRA1; SRXX2; SRXY10 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_000346.2
ATCGTCGACCCACGCGTCCGAAGCGGAGCTCGAAACTGACTGGAAACTTCAGTGGCGCGG
AGACTCGCCAGTTTCAACCCCGGAAACTTTTCTTTGCAGGAGGAGAAGAGAAGGGGTGCA AGCGCCCCCACTTTTGCTCTTTTTCCTCCCCTCCTCCTCCTCTCCAATTCGCCTCCCCCC ACTTGGAGCGGGCAGCTGTGAACTGGCCACCCCGCGCCTTCCTAAGTGCTCGCCGCGGTA GCCGGCCGACGCGCCAGCTTCCCCGGGAGCCGCTTGCTCCGCATCCGGGCAGCCGAGGGG AGAGGAGCCCGCGCCTCGAGTCCCCGAGCCGCCGCGGCTTCTCGCCTTTCCCGGCCACCA GCCCCCTGCCCCGGGCCCGCGTATGAATCTCCTGGACCCCTTCATGAAGATGACCGACGA GCAGGAGAAGGGCCTGTCCGGCGCCCCCAGCCCCACCATGTCCGAGGACTCCGCGGGCTC GCCCTGCCCGTCGGGCTCCGGCTCGGACACCGAGAACACGCGGCCCCAGGAGAACACGTT CCCCAAGGGCGAGCCCGATCTGAAGAAGGAGAGCGAGGAGGACAAGTTCCCCGTGTGCAT CCGCGAGGCGGTCAGCCAGGTGCTCAAAGGCTACGACTGGACGCTGGTGCCCATGCCGGT GCGCGTCAACGGCTCCAGCAAGAACAAGCCGCACGTCAAGCGGCCCATGAACGCCTTCAT GGTGTGGGCGCAGGCGGCGCGCAGGAAGCTCGCGGACCAGTACCCGCACTTGCACAACGC CGAGCTCAGCAAGACGCTGGGCAAGCTCTGGAGACTTCTGAACGAGAGCGAGAAGCGGCC CTTCGTGGAGGAGGCGGAGCGGCTGCGCGTGCAGCACAAGAAGGACCACCCGGATTACAA GTACCAGCCGCGGCGGAGGAAGTCGGTGAAGAACGGGCAGGCGGAGGCAGAGGAGGCCAC GGAGCAGACGCACATCTCCCCCAACGCCATCTTCAAGGCGCTGCAGGCCGACTCGCCACA CTCCTCCTCCGGCATGAGCGAGGTGCACTCCCCCGGCGAGCACTCGGGGCAATCCCAGGG CCCACCGACCCCACCCACCACCCCCAAAACCGACGTGCAGCCGGGCAAGGCTGACCTGAA GCGAGAGGGGCGCCCCTTGCCAGAGGGGGGCAGACAGCCCCCTATCGACTTCCGCGACGT GGACATCGGCGAGCTGAGCAGCGACGTCATCTCCAACATCGAGACCTTCGATGTCAACGA GTTTGACCAGTACCTGCCGCCCAACGGCCACCCGGGGGTGCCGGCCACGCACGGCCAGGT CACCTACACGGGCAGCTACGGCATCAGCAGCACCGCGGCCACCCCGGCGAGCGCGGGCCA CGTGTGGATGTCCAAGCAGCAGGCGCCGCCGCCACCCCCGCAGCAGCCCCCACAGGCCCC GCCGGCCCCGCAGGCGCCCCCGCAGCCGCAGGCGGCGCCCCCACAGCAGCCGGCGGCACC CCCGCAGCAGCCACAGGCGCACACGCTGACCACGCTGAGCAGCGAGCCGGGCCAGTCCCA GCGAACGCACATCAAGACGGAGCAGCTGAGCCCCAGCCACTACAGCGAGCAGCAGCAGCA CTCGCCCCAACAGATCGCCTACAGCCCCTTCAACCTCCCACACTACAGCCCCTCCTACCC GCCCATCACCCGCTCACAGTACGACTACACCGACCACCAGAACTCCAGCTCCTACTACAG CCACGCGGCAGGCCAGGGCACCGGCCTCTACTCCACCTTCACCTACATGAACCCCGCTCA GCGCCCCATGTACACCCCCATCGCCGACACCTCTGGGGTCCCTTCCATCCCGCAGACCCA CAGCCCCCAGCACTGGGAACAACCCGTCTACACACAGCTCACTCGACCTTGAGGAGGCCT CCCACGAAGGGCGAAGATGGCCGAGATGATCCTAAAAATAACCGAAGAAAGAGAGGACCA ACCAGAATTCCCTTTGGACATTTGTGTTTTTTTGTTTTTTTATTTTGTTTTGTTTTTTCT TCTTCTTCTTCTTCCTTAAAGACATTTAAGCTAAAGGCAACTCGTACCCAAATTTCCAAG ACACAAACATGACCTATCCAAGCGCATTACCCACTTGTGGCCAATCAGTGGCCAGGCCAA CCTTGGCTAAATGGAGCAGCGAAATCAACGAGAAACTGGACTTTTTAAACCCTCTTCAGA GCAAGCGTGGAGGATGATGGAGAATCGTGTGATCAGTGTGCTAAATCTCTCTGCCTGTTT GGACTTTGTAATTATTTTTTTAGCAGTAATTAAAGAAAAAAGTCCTCTGTGAGGAATATT CTCTATTTTAAATATTTTTAGTATGTACTGTGTATGATTCATTACCATTTTGAGGGGATT TATACATATTTTTAGATAAAATTAAATGCTCTTATTTTTCCAACAGCTAAACTACTCTTA GTTGAACAGTGTGCCCTAGCTTTTCTTGCAACCAGAGTATTTTTGTACAGATTTGCTTTC TCTTACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_000346 |
| Insert Size | 1530 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | no |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000346.2, NP_000337.1 |
| RefSeq Size | 3935 bp |
| RefSeq ORF | 1530 bp |
| Locus ID | 6662 |
| UniProt ID | P48436 |
| Domains | HMG |
| Protein Families | Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors |
| Gene Summary | The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq, Jul 2008] |
Citations (13)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
aarF domain containing kinase 5 gene promotes invasion and migration of lung cancer cells through ADCK5-SOX9-PTTG1 pathway
,Qiu, M;Li, G;Wang, P;Li, X;Lai, F;Luo, R;Liu, B;Lin, J;,
Exp. Cell Res.
,PubMed ID 32277958
[SOX9]
|
|
Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/ß-catenin signaling
,Leung, CO;Mak, WN;Kai, AK;Chan, KS;Lee, TK;Ng, IO;Lo, RC;,
Oncotarget
,PubMed ID 27105493
[Sox9]
|
|
Sox9 expression in carcinogenesis and its clinical significance in intrahepatic cholangiocarcinoma
,Matsushima, H;Kuroki, T;Kitasato, A;Adachi, T;Tanaka, T;Hirabaru, M;Hirayama, T;Kuroshima, N;Hidaka, M;Soyama, A;Takatsuki, M;Kinoshita, N;Sano, K;Nishida, N;Eguchi, S;,
Dig Liver Dis
,PubMed ID 26341967
[SOX9]
|
|
SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinoma
,Luanpitpong, S;Li, J;Manke, A;Brundage, K;Ellis, E;McLaughlin, SL;Angsutararux, P;Chanthra, N;Voronkova, M;Chen, YC;Wang, L;Chanvorachote, P;Pei, M;Issaragrisil, S;Rojanasakul, Y;,
Oncogene
,PubMed ID 26387547
[SOX9]
|
|
Transcriptional and structural control of cell identity genes
,Fan, ZP;,
Thesis
[SOX9]
|
|
Sry-type HMG box 18 contributes to the differentiation of bone marrow-derived mesenchymal stem cells to endothelial cells
,Ikhapoh, IA;Pelham, CJ;Agrawal, DK;,
Differentiation
,PubMed ID 25913202
[SOX9]
|
|
Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma
,Shakhova, O;Cheng, P;Mishra, PJ;Zingg, D;Schaefer, SM;Debbache, J;Häusel, J;Matter, C;Guo, T;Davis, S;Meltzer, P;Mihic-Probst, D;Moch, H;Wegner, M;Merlino, G;Levesque, MP;Dummer, R;Santoro, R;Cinelli, P;Sommer, L;,
PLoS Genet.
,PubMed ID 25629959
[SOX9]
|
|
The transcription factors Sox5 and Sox9 regulate Catsper1 gene expression
,Mata-Rocha, M;Hernández-Sánchez, J;Guarneros, G;de la Chesnaye, E;Sánchez-Tusié, AA;Treviño, CL;Felix, R;Oviedo, N;,
FEBS Lett.
,PubMed ID 25101494
[SOX9]
|
|
Osteochondral Tissue Regeneration Through Polymeric Delivery of DNA Encoding for the SOX Trio and RUNX2
,Needham, CJ;Shah, SR;Dahlin, RL;Kinard, LA;Lam, J;Watson, BM;Lu, S;Kurtis Kasper, F;Mikos, AG;,
Acta Biomater
,PubMed ID 24854956
[SOX9]
|
|
Development of a Polymeric Gene Delivery Vector for Application in Osteochondral Tissue Engineering
,Needham, CJ;,
Thesis
[SOX9]
|
|
High efficiency transfection of embryonic limb mesenchyme with plasmid DNA using square wave pulse electroporation and sucrose buffer
,Bobick, BE;Alexander, PG;Tuan, RS;,
BioTechniques, Feb 2014.
[SOX9]
|
|
KLF4 and SOX9 Transcription Factors Antagonize ?-Catenin and Inhibit TCF-Activity In Cancer Cells
,null,
Biochimica et biophysica acta
,PubMed ID 22766303
[SOX9]
|
|
A misplaced lncRNA causes brachydactyly in humans
,null,
The Journal of Clinical Investigation
,PubMed ID 23093776
[SOX9]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208944 | SOX9 (Myc-DDK-tagged)-Human SRY (sex determining region Y)-box 9 (SOX9) |
CNY 5,688.00 |
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| RC208944L1 | Lenti-ORF clone of SOX9 (Myc-DDK-tagged)-Human SRY (sex determining region Y)-box 9 (SOX9) |
CNY 8,088.00 |
|
| RC208944L2 | Lenti-ORF clone of SOX9 (mGFP-tagged)-Human SRY (sex determining region Y)-box 9 (SOX9) |
CNY 6,460.00 |
|
| RC208944L3 | Lenti-ORF clone of SOX9 (Myc-DDK-tagged)-Human SRY (sex determining region Y)-box 9 (SOX9) |
CNY 8,088.00 |
|
| RC208944L4 | Lenti-ORF clone of SOX9 (mGFP-tagged)-Human SRY (sex determining region Y)-box 9 (SOX9) |
CNY 8,088.00 |
|
| RG208944 | SOX9 (tGFP-tagged) - Human SRY (sex determining region Y)-box 9 (SOX9) |
CNY 7,288.00 |
