Bonzo (CXCR6) (NM_006564) Human Untagged Clone

CAT#: SC321785

CXCR6 (untagged)-Human chemokine (C-X-C motif) receptor 6 (CXCR6)



  "NM_006564" in other vectors (6)

CNY 3,656.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
Rabbit Polyclonal Anti-CXCR6 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms BONZO; CD186; CDw186; STRL33; TYMSTR
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_006564.1 CATCTCTGCTGGTGTTCATCAGAACAGACACCATGGCAGAGCATGATTACCATGAAGACT
ATGGGTTCAGCAGTTTCAATGACAGCAGCCAGGAGGAGCATCAAGACTTCCTGCAGTTCA
GCAAGGTCTTTCTGCCCTGCATGTACCTGGTGGTGTTTGTCTGTGGTCTGGTGGGGAACT
CTCTGGTGCTGGTCATATCCATCTTCTACCATAAGTTGCAGAGCCTGACGGATGTGTTCC
TGGTGAACCTACCCCTGGCTGACCTGGTGTTTGTCTGCACTCTGCCCTTCTGGGCCTATG
CAGGCATCCATGAATGGGTGTTTGGCCAGGTCATGTGCAAGAGCCTACTGGGCATCTACA
CTATTAACTTCTACACGTCCATGCTCATCCTCACCTGCATCACTGTGGATCGTTTCATTG
TAGTGGTTAAGGCCACCAAGGCCTACAACCAGCAAGCCAAGAGGATGACCTGGGGCAAGG
TCACCAGCTTGCTCATCTGGGTGATATCCCTGCTGGTTTCCTTGCCCCAAATTATCTATG
GCAATGTCTTTAATCTCGACAAGCTCATATGTGGTTACCATGACGAGGCAATTTCCACTG
TGGTTCTTGCCACCCAGATGACACTGGGGTTCTTCTTGCCACTGCTCACCATGATTGTCT
GCTATTCAGTCATAATCAAAACACTGCTTCATGCTGGAGGCTTCCAGAAGCACAGATCTC
TAAAGATCATCTTCCTGGTGATGGCTGTGTTCCTGCTGACCCAGATGCCCTTCAACCTCA
TGAAGTTCATCCGCAGCACACACTGGGAATACTATGCCATGACCAGCTTTCACTACACCA
TCATGGTGACAGAGGCCATCGCATACCTGAGGGCCTGCCTTAACCCTGTGCTCTATGCCT
TTGTCAGCCTGAAGTTTCGAAAGAACTTCTGGAAACTTGTGAAGGACATTGGTTGCCTCC
CTTACCTTGGGGTCTCACATCAATGGAAATCTTCTGAGGACAATTCCAAGACTTTTTCTG
CCTCCCACAATGTGGAGGCCACCAGCATGTTCCAGTTATAGGCCTTGCCAGGGTTTCGAG
AAGCTGCTCTGGAATTTGCAAGGCATGGCTGTGCCCTCTTGATGTGGTGAGGCAGGCTTT
GTTTATAGCTTGCGCATTCTCATGGAGAAGTTATCAGACACTCTGGCTGGTTTGGAATGC
TTCTTCTCAGGCATGAACATGTACTGTTCTCTTCTTGAACACTCATGCTGAAAGCCCAAG
TAGGGGGTCTAAAATTTTTAAGGACTTTCCTTCCTCCATCTCCAAGAATGCTGAAACCAA
GGGGGATGACATGTGACTCCTATGATCTCAGGTTCTCCTTGATTGGGACTGGGGCTGAAG
GTTGAAGAGGTGAGCACGGCCAACAAAGCTGTTGATGGTAGGTGGCACACTGGGTGCCCA
AGCTCAGAAGGCTCTTCTGACTACTGGGCAAAGAGTGTAGATCAGAGCAGCAGTGAAAAC
AAGTGCTGGCACCACCAGGCACCTCACAGAAATGAGATCAGGCTCTGCCTCACCTTGGGG
CTTGACTTTTGTATAGGTAGATGTTCAGATTGCTTTGATTAATCCAGAATAACTAGCACC
AGGGACTATGAATGGGCAAAACTGAATTATAAGAGGCTGATAATTCCAGTGGTCCATGGA
ATGCTTGAAAAATGTGCAAAACAGCGTTTAAGACTGTAATGAATCTAAGCAGCATTTCTG
AAGTGGACTCTTTGGTGGCTTTGCATTTTAAAAATGAAATTTTCCAATGTCTGCCACACA
AACGTATGTAAATGTATATACCCACACACATACACACATATGTCATATATTACTAGCATA
TGAATTTCATAGCTAAGAAATAAAACTGTTAAAGTCTCAAAAAAAAAAAAAAAAAAAAAA
AAA
Restriction Sites Please inquire     
ACCN NM_006564
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_006564.1, NP_006555.1
RefSeq Size 1953 bp
RefSeq ORF 1029 bp
Locus ID 10663
UniProt ID O00574
Domains 7tm_1
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction
Gene Summary The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. [provided by RefSeq, Aug 2020]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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