Syntrophin alpha 1 (SNTA1) (NM_003098) Human Untagged Clone
CAT#: SC321683
SNTA1 (untagged)-Human syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) (SNTA1)
CNY 3,768.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | dJ1187J4.5; LQT12; SNT1; TACIP1 |
Vector | pCMV6-AC |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>OriGene sequence for NM_003098.2
GGCGGCTGGCCCAGCCGGGCCCCCGCTGCCCTCTGCCCTGGGCGCTTGGTCGGAGCGGGC
TGGGCAAAGCGGGACAGGGCGAGCGCGGCGGCCCGGGGGCTCGGAGGCGAAGATGGCGTC CGGCAGGCGCGCCCCGCGCACCGGGCTGCTGGAGCTGCGCGCCGGGGCGGGCTCGGGGGC CGGCGGCGAGCGATGGCAGCGGGTGCTGCTGAGTCTGGCGGAGGACGTGCTGACCGTGAG CCCCGCCGACGGCGACCCTGGTCCCGAGCCCGGCGCTCCGCGGGAGCAGGAGCCCGCGCA GCTCAACGGCGCCGCGGAGCCGGGCGCCGGGCCCCCGCAGCTGCCAGAGGCGCTACTGCT CCAGCGGCGCCGCGTGACGGTGCGCAAGGCCGACGCCGGTGGGCTGGGCATCAGCATCAA AGGCGGCCGGGAGAACAAGATGCCTATTCTCATTTCCAAGATCTTCAAGGGATTGGCAGC TGACCAGACAGAGGCCCTTTTTGTGGGGGATGCCATCCTGTCTGTGAATGGGGAAGACTT GTCCTCTGCTACCCATGATGAGGCGGTGCAGGTCCTCAAGAAGACAGGCAAGGAGGTGGT GCTGGAGGTCAAGTATATGAAGGACGTCTCACCGTATTTCAAGAACTCTACTGGTGGGAC CTCGGTCGGCTGGGACTCACCTCCTGCCTCACCCCTTCAGCGGCAGCCTTCCTCCCCTGG CCCCACACCCCGGAACTTCAGCGAGGCCAAACACATGTCCTTGAAGATGGCATATGTCTC GAAGAGGTGCACCCCCAATGACCCGGAGCCCAGGTATCTGGAGATCTGCTCGGCAGATGG TCAAGACACCCTCTTCCTGAGGGCCAAGGATGAGGCTAGTGCGAGGTCGTGGGCGACTGC CATCCAAGCCCAGGTCAATACTCTGACGCCGCGGGTCAAGGATGAGCTGCAGGCACTGTT GGCAGCCACCAGCACAGCTGGGAGCCAGGACATCAAGCAGATTGGCTGGCTAACTGAGCA GCTGCCCAGTGGGGGCACAGCCCCCACCCTGGCCCTGCTAACTGAAAAGGAACTGCTCCT CTACTTGTCTCTCCCCGAGACCCGCGAGGCCCTGAGCCGGCCAGCCCGTACTGCCCCACT CATCGCCACCAGACTGGTGCACTCAGGCCCCTCCAAGGGCTCAGTGCCCTACGATGCAGA GCTCTCTTTTGCCCTGCGCACGGGCACGCGTCACGGTGTGGACACTCACCTGTTCAGCGT GGAGTCACCGCAGGAGCTGGCTGCCTGGACCCGCCAGCTTGTGGATGGCTGTCACCGGGC CGCCGAGGGTGTGCAGGAGGTGTCTACAGCCTGCACGTGGAATGGGCGTCCCTGCAGCCT GTCTGTGCACATCGACAAGGGCTTCACACTGTGGGCGGCTGAGCCAGGTGCAGCCCGAGC TGTGCTCCTGCGACAGCCCTTCGAGAAGCTGCAGATGTCTTCAGATGACGGTGCCAGTCT CCTTTTCCTGGATTTTGGAGGTGCTGAAGGCGAGATCCAGCTGGACCTGCACTCGTGTCC CAAAACCATAGTCTTCATCATCCACTCCTTCCTGTCGGCCAAAGTCACCCGCCTCGGGCT GTTGGCCTAGAAGTCGCCGGATGCACTAGCCCTGAAGAGGGGTGTCCATGACATGGCCTG AGCTGGGCCTCCACCGACTGCCTGCTCACCCCTGGGCTGAGGGAAGGGAGAGGAGAGGAA CAAGGGCCTCCGAAACCCCAACCCTGAGGGAGACTGGATTGGTCTTGGGGCCCAGGACCC AGACGCAGGACAGAGTGGACTCTGCCTGTGATGGGGTGGCCTTCCTGCTGCCCCCCTCCA CCAGTGCCTTTTGCAGAGAGATATTTTGTGTACACAGAAGCCATTCCGAGTCTGGGACCT GCCCCTGTGCGGATCCTGACCCCAGCCAACAGCTGAGCTGCCGGGCCTCCTCGAGGCCCC TAAGCCACCCCCAGAGGTCCCATCTGAAGCTGGAGTACCCTGGGGTCAGCAGCAAGAGAA AGAAGAGGAGATTTTCTGTTTGTTTTTCCCCTCAGCCCTGCCACCGTGGGGAGTCTGGTT TTTCTCTTCATCCTGTCTCTCTCCTCCTTACTCTTGGATAAATAAACAGCCTGTGAGCAC ACAGGCAGCCCGGAAAAAAAAAAAAAAAA |
Restriction Sites | Please inquire |
ACCN | NM_003098 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_003098.2, NP_003089.1 |
RefSeq Size | 2345 bp |
RefSeq ORF | 1518 bp |
Locus ID | 6640 |
UniProt ID | Q13424 |
Domains | PDZ, PH |
Gene Summary | Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204480 | SNTA1 (Myc-DDK-tagged)-Human syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) (SNTA1) |
CNY 3,760.00 |
|
RC204480L1 | Lenti ORF clone of Human syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) (SNTA1), Myc-DDK-tagged |
CNY 6,160.00 |
|
RC204480L2 | Lenti ORF clone of Human syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) (SNTA1), mGFP tagged |
CNY 6,460.00 |
|
RC204480L3 | Lenti ORF clone of Human syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) (SNTA1), Myc-DDK-tagged |
CNY 6,460.00 |
|
RC204480L4 | Lenti ORF clone of Human syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) (SNTA1), mGFP tagged |
CNY 6,460.00 |
|
RG204480 | SNTA1 (tGFP-tagged) - Human syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) (SNTA1) |
CNY 5,360.00 |
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