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Claudin 1 (CLDN1) (NM_021101) Human Untagged Clone
CAT＃: SC321664
CLDN1 (untagged)-Human claudin 1 (CLDN1)
CNY 2,400.00
CNY 2,950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CLD1; ILVASC; SEMP1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_021101.3
CCAGACTCCAGCGCCGCCCCGGGCGCGGACCCCAACCCCGACCCAGAGCTTCTCCAGCGG
CGGCGCAGCGAGCAGGGCTCCCCGCCTTAACTTCCTCCGCGGGGCCCAGCCACCTTCGGG AGTCCGGGTTGCCCACCTGCAAACTCTCCGCCTTCTGCACCTGCCACCCCTGAGCCAGCG CGGGCGCCCGAGCGAGTCATGGCCAACGCGGGGCTGCAGCTGTTGGGCTTCATTCTCGCC TTCCTGGGATGGATCGGCGCCATCGTCAGCACTGCCCTGCCCCAGTGGAGGATTTACTCC TATGCCGGCGACAACATCGTGACCGCCCAGGCCATGTACGAGGGGCTGTGGATGTCCTGC GTGTCGCAGAGCACCGGGCAGATCCAGTGCAAAGTCTTTGACTCCTTGCTGAATCTGAGC AGCACATTGCAAGCAACCCGTGCCTTGATGGTGGTTGGCATCCTCCTGGGAGTGATAGCA ATCTTTGTGGCCACCGTTGGCATGAAGTGTATGAAGTGCTTGGAAGACGATGAGGTGCAG AAGATGAGGATGGCTGTCATTGGGGGCGCGATATTTCTTCTTGCAGGTCTGGCTATTTTA GTTGCCACAGCATGGTATGGCAATAGAATCGTTCAAGAATTCTATGACCCTATGACCCCA GTCAATGCCAGGTACGAATTTGGTCAGGCTCTCTTCACTGGCTGGGCTGCTGCTTCTCTC TGCCTTCTGGGAGGTGCCCTACTTTGCTGTTCCTGTCCCCGAAAAACAACCTCTTACCCA ACACCAAGGCCCTATCCAAAACCTGCACCTTCCAGCGGGAAAGACTACGTGTGACACAGA GGCAAAAGGAGAAAATCATGTTGAAACAAACCGAAAATGGACATTGAGATACTATCATTA ACATTAGGACCTTAGAATTTTGGGTATTGTAATCTGAAGTATGGTATTACAAAACAAACA AACAAACAAAAAACCCATGTGTTAAAATACTCAGTGCTAAACATGGCTTAATCTTATTTT ATCTTCTTTCCTCAATATAGGAGGGAAGATTTTTCCATTTGTATTACTGCTTCCCATTGA GTAATCATACTCAACTGGGGGAAGGGGTGCTCCTTAAATATATATAGATATGTATATATA CATGTTTTTCTATTAAAAATAGACAGTAAAATACTATTCTCATTATGTTGATACTAGCAT ACTTAAAATATCTCTAAAATAGGTAAATGTATTTAATTCCATATTGATGAAGATGTTAAA AAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_021101 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021101.3, NP_066924.1 |
| RefSeq Size | 3445 bp |
| RefSeq ORF | 636 bp |
| Locus ID | 9076 |
| UniProt ID | O95832 |
| Domains | PMP22_Claudin |
| Protein Families | Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Tight junction |
| Gene Summary | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry
,Riva, L;Song, OR;Prentoe, J;Helle, F;L'homme, L;Gattolliat, CH;Vandeputte, A;Fénéant, L;Belouzard, S;Baumert, TF;Asselah, T;Bukh, J;Brodin, P;Cocquerel, L;Rouillé, Y;Dubuisson, J;,
J. Virol.
,PubMed ID 29491159
[CLDN1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204466 | CLDN1 (Myc-DDK-tagged)-Human claudin 1 (CLDN1) |
CNY 2,400.00 |
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| RC204466L1 | Lenti ORF clone of Human claudin 1 (CLDN1), Myc-DDK-tagged |
CNY 4,800.00 |
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| RC204466L2 | Lenti ORF clone of Human claudin 1 (CLDN1), mGFP tagged |
CNY 5,890.00 |
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| RC204466L3 | Lenti ORF clone of Human claudin 1 (CLDN1), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC204466L4 | Lenti ORF clone of Human claudin 1 (CLDN1), mGFP tagged |
CNY 4,800.00 |
|
| RG204466 | CLDN1 (tGFP-tagged) - Human claudin 1 (CLDN1) |
CNY 4,000.00 |
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