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ALDH1A1 (NM_000689) Human Untagged Clone
CAT＃: SC321535
ALDH1A1 (untagged)-Human aldehyde dehydrogenase 1 family, member A1 (ALDH1A1)
CNY 3,736.00
| Cited in 6 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ALDC; ALDH-E1; ALDH1; ALDH11; HEL-9; HEL-S-53e; HEL12; PUMB1; RALDH1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_000689.3
CTGTGTTCCAGGAGCCGAATCAGAAATGTCATCCTCAGGCACGCCAGACTTACCTGTCCT
ACTCACCGATTTGAAGATTCAATATACTAAGATCTTCATAAACAATGAATGGCATGATTC AGTGAGTGGCAAGAAATTTCCTGTCTTTAATCCTGCAACTGAGGAGGAGCTCTGCCAGGT AGAAGAAGGAGATAAGGAGGATGTTGACAAGGCAGTGAAGGCCGCAAGACAGGCTTTTCA GATTGGATCCCCGTGGCGTACTATGGATGCTTCCGAGAGGGGGCGACTATTATACAAGTT GGCTGATTTAATCGAAAGAGATCGTCTGCTGCTGGCGACAATGGAGTCAATGAATGGTGG AAAACTCTATTCCAATGCATATCTGAATGATTTAGCAGGCTGCATCAAAACATTGCGCTA CTGTGCAGGTTGGGCTGACAAGATCCAGGGCCGTACAATACCAATTGATGGAAATTTTTT TACATATACAAGACATGAACCTATTGGTGTATGTGGCCAAATCATTCCTTGGAATTTCCC GTTGGTTATGCTCATTTGGAAGATAGGGCCTGCACTGAGCTGTGGAAACACAGTGGTTGT CAAACCAGCAGAGCAAACTCCTCTCACTGCTCTCCACGTGGCATCTTTAATAAAAGAGGC AGGGTTTCCTCCTGGAGTAGTGAATATTGTTCCTGGTTATGGGCCTACAGCAGGGGCAGC CATTTCTTCTCACATGGATATAGACAAAGTAGCCTTCACAGGATCAACAGAGGTTGGCAA GTTGATCAAAGAAGCTGCCGGGAAAAGCAATCTGAAGAGGGTGACCCTGGAGCTTGGAGG AAAGAGCCCTTGCATTGTGTTAGCTGATGCCGACTTGGACAATGCTGTTGAATTTGCACA CCATGGGGTATTCTACCACCAGGGCCAGTGTTGTATAGCCGCATCCAGGATTTTTGTGGA AGAATCAATTTATGATGAGTTTGTTCGAAGGAGTGTTGAGCGGGCTAAGAAGTATATCCT TGGAAATCCTCTGACCCCAGGAGTCACTCAAGGCCCTCAGATTGACAAGGAACAATATGA TAAAATACTTGACCTCATTGAGAGTGGGAAGAAAGAAGGGGCCAAACTGGAATGTGGAGG AGGCCCGTGGGGGAATAAAGGCTACTTTGTCCAGCCCACAGTGTTCTCTAATGTTACAGA TGAGATGCGCATTGCCAAAGAGGAGATTTTTGGACCAGTGCAGCAAATCATGAAGTTTAA ATCTTTAGATGACGTGATCAAAAGAGCAAACAATACTTTCTATGGCTTATCAGCAGGAGT GTTTACCAAAGACATTGATAAAGCCATAACAATCTCCTCTGCTCTGCAGGCAGGAACAGT GTGGGTGAATTGCTATGGCGTGGTAAGTGCCCAGTGCCCCTTTGGTGGATTCAAGATGTC TGGAAATGGAAGAGAACTGGGAGAGTACGGTTTCCATGAATATACAGAGGTCAAAACAGT CACAGTGAAAATCTCTCAGAAGAACTCATAAAGAAAATACAAGAGTGGAGAGAAGCTCTT CAATAGCTAAGCATCTCCTTACAGTCACTAATATAGTAGATTTTAAAGACAAAATTTTTC TTTTCTTGATTTTTTTAAACATAAGCTAAATCATATTAGTATTAATACTACCCATAGAAA ACTTGACATGTAGCTTCTTCTGAAAGAATTATTTGCCTTCTGAAATGTGACCCCCAAGTC CTATCCTAAATAAAAAAAGACAAATTCGGATGTATGATCTCTCTAGCTTTGTCATAGTTA TGTGATTTTCCTTTGTAGCTACTTTTGCAGGATAATAATTTTATAGAAAAGGAACAGTTG CATTTAGCTTCTTTCCCTTAGTGACTCTTGAAGTACTTAACATACACGTTAACTGTAGAG TAAATTGCTCTGTTCCCAGTAGTTATAAAGTCCTTGGACTGTTTTGAAAAGTTTCCTAGG ATGTCATGTCTGCTTGTCAAAAGAAATAATCCCTGTAATATTTAGCTGTAAACTGAATAT AAAGCTTAATAAAAACAACCTTGCATGAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_000689 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000689.3, NP_000680.2 |
| RefSeq Size | 2116 bp |
| RefSeq ORF | 1506 bp |
| Locus ID | 216 |
| UniProt ID | P00352 |
| Domains | aldedh |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
| Protein Pathways | Metabolic pathways, Retinol metabolism |
| Gene Summary | The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011] |
Citations (6)
| The use of this cDNA Clones has been cited in the following citations: |
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Pharmacological inhibition of ALDH1A enzymes suppresses weight gain in a mouse model of diet-induced obesity
,null,
Obesity research & clinical practice
,PubMed ID 28919001
[ALDH1A1]
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Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations
,Arnold, SL;Kent, T;Hogarth, CA;Schlatt, S;Prasad, B;Haenisch, M;Walsh, T;Muller, CH;Griswold, MD;Amory, JK;Isoherranen, N;,
J. Lipid Res.
,PubMed ID 25502770
[ALDH1A1]
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Aldehyde dehydrogenase-1a1 induces oncogene suppressor genes in B cell populations
,Yasmeen, R;Meyers, JM;Alvarez, CE;Thomas, JL;Bonnegarde-Bernard, A;Alder, H;Papenfuss, TL;Benson, DM;Boyaka, PN;Ziouzenkova, O;,
,PubMed ID 24080087
[ALDH1A1]
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Aldehyde dehydrogenase 1A1—a new mediator of resistance to temozolomide in glioblastoma
,Andrea Schäfer, Julian Teufel, Florian Ringel, Marcus Bettstetter, Ingrid Hoepner, Michael Rasper, Jens Gempt, Julia Koeritzer, Friederike Schmidt-Graf, Bernhard Meyer, Christoph P. Beier, and Jürgen Schlegel,
Neuro Oncology, Dec 2012; 14: 1452 - 1464.
[ALDH1A1]
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Studying fatty aldehyde metabolism in living cells with pyrene-labeled compounds
,Markus A. Keller, Katrin Watschinger, Karsten Lange, Georg Golderer, Gabriele Werner-Felmayer, Albin Hermetter, Ronald J. A. Wanders, and Ernst R. Werner,
J. Lipid Res., Jul 2012; 53: 1410 - 1416.
[ALDH1A1]
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Concerted Action of Aldehyde Dehydrogenases Influences Depot-Specific Fat Formation
,Barbara Reichert, Rumana Yasmeen, Shanmugam M. Jeyakumar, Fangping Yang, Thomas Thomou, Hansjuerg Alder, Gregg Duester, Andrei Maiseyeu, Georgeta Mihai, Earl H. Harrison, Sanjay Rajagopalan, James L. Kirkland, and Ouliana Ziouzenkova,
Mol. Endocrinol., May 2011; 25: 799 - 809
[Aldh1a1]
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Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200723 | ALDH1A1 (Myc-DDK-tagged)-Human aldehyde dehydrogenase 1 family, member A1 (ALDH1A1) |
CNY 3,728.00 |
|
| RC200723L1 | Lenti ORF clone of Human aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), Myc-DDK-tagged |
CNY 6,128.00 |
|
| RC200723L2 | Lenti ORF clone of Human aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), mGFP tagged |
CNY 6,460.00 |
|
| RC200723L3 | Lenti ORF clone of Human aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), Myc-DDK-tagged |
CNY 6,128.00 |
|
| RC200723L4 | Lenti ORF clone of Human aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), mGFP tagged |
CNY 6,128.00 |
|
| RG200723 | ALDH1A1 (tGFP-tagged) - Human aldehyde dehydrogenase 1 family, member A1 (ALDH1A1) |
CNY 5,320.00 |
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