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AKAP8L (NM_014371) Human Untagged Clone
CAT＃: SC321388
AKAP8L (untagged)-Human A kinase (PRKA) anchor protein 8-like (AKAP8L)
CNY 4,816.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HA95; HAP95; NAKAP; NAKAP95 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_014371.2
GTTCAGAGCAGCAGAAGCCGGCGTCGTCGGATGTTGTGTTGCCCGCCACCATGAGCTACA
CAGGCTTTGTCCAGGGATCTGAAACCACTTTGCAGTCGACATACTCGGATACCAGCGCTC AGCCCACCTGTGATTATGGATATGGAACTTGGAACTCTGGGACAAATAGAGGCTACGAGG GCTATGGCTATGGCTATGGCTATGGCCAGGATAACACCACCAACTATGGGTATGGTATGG CCACTTCACACTCTTGGGAAATGCCTAGCTCTGACACAAATGCAAACACTAGTGCCTCGG GTAGCGCCAGTGCCGATTCCGTTTTATCCAGAATTAACCAGCGCTTAGATATGGTGCCGC ATTTGGAGACAGACATGATGCAAGGAGGCGTGTACGGCTCAGGTGGAGAAAGGTATGACT CTTATGAGTCCTGCGACTCGAGGGCCGTCCTGAGTGAGCGCGACCTGTACCGGTCAGGCT ATGACTACAGCGAGCTTGACCCTGAGATGGAAATGGCCTATGAGGGCCAATACGATGCCT ACCGCGACCAGTTCCGCATGCGTGGCAACGACACCTTCGGTCCCAGGGCACAGGGCTGGG CCCGGGATGCCCGGAGCGGCCGGCCAATGGCCTCAGGCTATGGGCGCATGTGGGAAGACC CCATGGGGGCCCGGGGCCAGTGCATGTCTGGTGCCTCTCGGCTGCCCTCCCTCTTCTCCC AGAACATCATCCCCGAGTACGGCATGTTCCAGGGCATGCGAGGTGGGGGCGCCTTCCCGG GCGGCTCCCGCTTTGGTTTCGGGTTTGGCAATGGCATGAAGCAGATGAGGCGGACCTGGA AGACCTGGACCACAGCCGACTTCCGAACCAAGAAGAAGAAGAGAAAGCAGGGCGGCAGTC CTGATGAGCCAGATAGCAAAGCCACCCGCACGGACTGCTCGGACAACAGCGACTCAGACA ATGATGAGGGCACCGAGGGGGAAGCCACAGAGGGCCTTGAAGGCACCGAGGCTGTGGAGA AGGGCTCCAGAGTGGACGGAGAGGATGAGGAGGGAAAAGAGGATGGGAGAGAAGAAGGCA AAGAGGATCCAGAGAAGGGGGCCCTAACCACCCAGGATGAAAATGGCCAGACCAAGCGCA AGTTGCAGGCAGGCAAGAAGAGTCAGGACAAGCAGAAAAAGCGGCAGCGAGACCGCATGG TGGAAAGGATCCAGTTTGTGTGTTCTCTGTGCAAATACCGGACCTTCTATGAGGACGAGA TGGCCAGCCATCTTGACAGCAAGTTCCACAAGGAACACTTTAAGTACGTAGGCACCAAGC TCCCTAAGCAGACGGCTGACTTTCTGCAGGAGTACGTCACTAACAAGACCAAGAAGACAG AGGAGCTCCGAAAAACCGTGGAGGACCTTGATGGCCTCATCCAGCAAATCTACAGAGACC AGGATCTGACCCAGGAAATTGCCATGGAGCATTTTGTGAAGAAGGTGGAGGCAGCCCATT GTGCAGCCTGCGACCTCTTCATTCCCATGCAGTTTGGGATCATCCAGAAGCATCTGAAGA CCATGGATCACAACCGGAACCGCAGGCTCATGATGGAGCAGTCCAAGAAGTCCTCCCTCA TGGTGGCCCGCAGTATTCTCAACAACAAGCTCATCAGCAAGAAGCTGGAGCGCTACCTGA AGGGCGAGAACCCTTTCACCGACAGCCCCGAGGAGGAGAAGGAGCAGGAGGAGGCTGAGG GCGGTGCCCTGGACGAGGGGGCGCAGGGCGAAGCGGCAGGGATCTCGGAGGGCGCAGAGG GCGTGCCGGCGCAGCCTCCCGTGCCCCCAGAGCCAGCCCCCGGGGCCGTGTCGCCGCCAC CGCCGCCGCCCCCAGAGGAGGAGGAGGAGGGCGCCGTGCCCTTGCTGGGAGGGGCGCTGC AACGCCAGATCCGCGGCATCCCGGGCCTCGACGTGGAGGACGACGAGGAGGGCGGCGGGG GCGCCCCGTGACCCGAGCTCGGGGCGGGCGGAGCCCGCGTGGCCGAAGCTGGAAACCAAA CCTAATAAAGTTTTCCCATCCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_014371 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014371.2, NP_055186.2 |
| RefSeq Size | 2136 bp |
| RefSeq ORF | 1941 bp |
| Locus ID | 26993 |
| UniProt ID | Q9ULX6 |
| Domains | AKAP95 |
| Protein Families | Druggable Genome |
| Gene Summary | Could play a role in constitutive transport element (CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export (PubMed:10748171, PubMed:11402034). Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA (PubMed:10761695, PubMed:11884601). May be involved in nuclear envelope breakdown and chromatin condensation. May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis (PubMed:11034899). May regulate the initiation phase of DNA replication when associated with TMPO isoform Beta (PubMed:12538639). Required for cell cycle G2/M transition and histone deacetylation during mitosis. In mitotic cells recruits HDAC3 to the vicinity of chromatin leading to deacetylation and subsequent phosphorylation at 'Ser-10' of histone H3; in this function seems to act redundantly with AKAP8 (PubMed:16980585). May be involved in regulation of pre-mRNA splicing (PubMed:17594903).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200233 | AKAP8L (Myc-DDK-tagged)-Human A kinase (PRKA) anchor protein 8-like (AKAP8L) |
CNY 4,808.00 |
|
| RC200233L3 | Lenti ORF clone of Human A kinase (PRKA) anchor protein 8-like (AKAP8L), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200233L4 | Lenti ORF clone of Human A kinase (PRKA) anchor protein 8-like (AKAP8L), mGFP tagged |
CNY 5,890.00 |
|
| RG200233 | AKAP8L (tGFP-tagged) - Human A kinase (PRKA) anchor protein 8-like (AKAP8L) |
CNY 6,408.00 |
