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PLEKHO1 (NM_016274) Human Untagged Clone
CAT＃: SC321205
PLEKHO1 (untagged)-Human pleckstrin homology domain containing, family O member 1 (PLEKHO1)
CN¥ 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CKIP-1; CKIP1; JBP; OC120 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_016274.3
GGGGAAGGAGCCCCCGCGGTGCCGCCGAGGCCCCGACGCGGGGCCGCCCCTCGGCTCGCC
GCCCCGCGCCCGCGCCCGCTGGGAATGATGAAGAAGAACAATTCCGCCAAGCGGGGACCT CAGGATGGAAACCAGCAGCCTGCACCGCCCGAGAAGGTCGGCTGGGTCCGGAAATTCTGC GGGAAAGGGATTTTCAGGGAGATTTGGAAAAACCGCTATGTGGTGCTGAAAGGGGACCAG CTCTACATCTCTGAGAAGGAGGTAAAAGATGAGAAAAATATTCAAGAGGTATTTGACCTG AGTGACTATGAGAAGTGTGAAGAGCTCCGGAAGTCCAAGAGCAGGAGCAAGAAAAATCAT AGCAAGTTTACTCTTGCCCACTCCAAACAGCCCGGTAACACGGCACCCAACCTGATCTTC CTGGCAGTGAGTCCAGAAGAGAAGGAATCGTGGATCAATGCCCTCAACTCTGCCATCACC CGAGCCAAGAACCGTATCTTGGATGAGGTCACCGTTGAGGAGGACAGCTATCTTGCCCAT CCCACTCGAGACAGGGCAAAAATCCAGCACTCCCGCCGCCCCCCAACAAGGGGACACCTA ATGGCTGTGGCTTCCACCTCTACCTCGGATGGGATGCTGACCTTGGACTTGATCCAAGAG GAAGACCCTTCCCCTGAGGAACCAACCTCTTGTGCTGAGAGCTTTCGGGTTGACCTGGAC AAGTCTGTGGCCCAGCTGGCAGGGAGCCGGCGGAGAGCGGACTCAGACCGCATCCAGCCC TCCGCAGACCGGGCAAGCAGTCTCTCCCGACCTTGGGAAAAAACAGACAAAGGGGCCACC TACACCCCCCAGGCACCCAAGAAGTTGACGCCCACAGAGAAAGGCCGCTGCGCCTCCCTG GAGGAGATCCTATCTCAGCGGGATGCTGCCTCTGCCCGCACCCTCCAGCTGCGGGCTGAG GAACCCCCAACCCCTGCCCTCCCCAACCCGGGGCAGCTGTCCCGGATCCAGGACCTGGTA GCAAGGAAACTGGAGGAGACTCAGGAGCTTCTGGCAGAGGTTCAGGGACTGGGAGATGGG AAGCGAAAGGCCAAGGACCCCCCTCGGTCTCCGCCGGATTCTGAGTCAGAGCAGCTGCTG CTGGAGACGGAACGGCTGCTGGGAGAGGCATCATCGAATTGGAGCCAGGCAAAGAGGGTG CTGCAGGAGGTCAGGGAGCTGAGAGACCTGTACAGACAGATGGACCTGCAGACCCCGGAC TCCCACCTCAGACAGACCACCCCGCACAGTCAGTACCGGAAGAGCCTGATGTGAGGGCAG GGTGGGGTCTGGAACTTGTCGGGTTGGACAGACTCTTATCTCCGTGTTGCTGGATAAAGC TTTTTTATTTACCTCAATCAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_016274 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016274.3, NP_057358.2 |
| RefSeq Size | 1633 bp |
| RefSeq ORF | 1230 bp |
| Locus ID | 51177 |
| UniProt ID | Q53GL0 |
| Domains | PH |
| Gene Summary | Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203969 | PLEKHO1 (Myc-DDK-tagged)-Human pleckstrin homology domain containing, family O member 1 (PLEKHO1) |
CN¥ 3,656.00 |
|
| RC203969L3 | Lenti ORF clone of Human pleckstrin homology domain containing, family O member 1 (PLEKHO1), Myc-DDK-tagged |
CN¥ 5,890.00 |
|
| RC203969L4 | Lenti ORF clone of Human pleckstrin homology domain containing, family O member 1 (PLEKHO1), mGFP tagged |
CN¥ 5,890.00 |
|
| RG203969 | PLEKHO1 (tGFP-tagged) - Human pleckstrin homology domain containing, family O member 1 (PLEKHO1) |
CN¥ 5,256.00 |
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