XPB (ERCC3) (NM_000122) Human Untagged Clone
CAT#: SC320745
ERCC3 (untagged)-Human excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3)
CNY 5,736.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | BTF2; GTF2H; RAD25; Ssl2; TFIIH; TTD2; XPB |
Vector | pCMV6-AC |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>OriGene sequence for NM_000122.1
CAGAGCGGATGCCGCGGCGGGCCTGTGGGAGCGGGGTCATCTTCTCTCTGCTGCTGTAGC
TGCCATGGGCAAAAGAGACCGAGCGGACCGCGACAAGAAGAAATCCAGGAAGCGGCACTA TGAGGATGAAGAGGATGATGAAGAGGACGCCCCGGGGAACGACCCTCAGGAAGCGGTTCC CTCGGCGGCGGGGAAGCAGGTGGATGAGTCAGGCACCAAAGTGGATGAATATGGAGCCAA GGACTACAGGCTGCAAATGCCGCTGAAGGACGACCACACCTCCAGGCCCCTCTGGGTGGC TCCCGATGGCCATATCTTCTTGGAAGCCTTCTCTCCAGTTTACAAATATGCCCAAGACTT CTTGGTGGCTATTGCAGAGCCAGTGTGCCGACCAACCCATGTGCATGAGTACAAACTAAC TGCCTACTCCTTGTATGCAGCTGTCAGCGTTGGGCTGCAAACCAGTGACATCACCGAGTA CCTCAGGAAGCTCAGCAAGACTGGAGTCCCTGATGGAATTATGCAGTTTATTAAGTTGTG TACTGTCAGCTATGGAAAAGTCAAGCTGGTCTTGAAGCACAACAGATACTTCGTTGAAAG TTGCCACCCTGATGTAATCCAGCATCTTCTCCAGGACCCCGTGATCCGAGAATGCCGCTT AAGAAACTCTGAAGGGGAGGCCACTGAGCTCATCACAGAGACTTTCACAAGCAAATCTGC CATTTCTAAGACTGCTGAAAGCAGTGGTGGGCCCTCCACTTCCCGAGTGACAGATCCACA GGGTAAATCTGACATCCCCATGGACCTGTTTGACTTCTATGAGCAAATGGACAAGGATGA AGAAGAAGAAGAAGAGACACAGACAGTGTCTTTTGAAGTCAAGCAGGAAATGATTGAGGA ACTCCAGAAACGTTGCATCCACCTGGAGTACCCTCTGTTGGCAGAATATGACTTCCGGAA TGATTCTGTCAACCCTGATATCAACATTGACCTAAAGCCCACAGCTGTCCTCAGACCCTA TCAGGAGAAGAGCTTGCGAAAGATGTTTGGAAACGGGCGTGCACGTTCGGGGGTCATTGT TCTTCCCTGCGGTGCTGGAAAGTCCCTGGTTGGTGTGACTGCTGCATGCACTGTCAGAAA ACGCTGTCTGGTGCTGGGCAACTCAGCTGTTTCTGTGGAGCAGTGGAAAGCCCAGTTCAA GATGTGGTCCACCATTGACGACAGCCAGATCTGCCGGTTCACCTCCGATGCCAAGGACAA GCCCATCGGCTGCTCCGTTGCCATTAGCACCTACTCCATGCTGGGCCACACCACCAAAAG GTCCTGGGAGGCCGAGCGAGTCATGGAGTGGCTCAAGACCCAGGAGTGGGGCCTCATGAT CCTGGATGAAGTGCACACCATACCAGCCAAGATGTTCCGAAGGGTGCTCACCATCGTGCA GGCCCACTGTAAGCTGGGTTTGACTGCGACCCTCGTCCGCGAAGATGACAAAATTGTGGA TTTAAATTTTCTGATTGGGCCTAAGCTCTACGAAGCCAACTGGATGGAGCTGCAGAATAA TGGCTACATCGCCAAAGTCCAGTGTGCTGAGGTCTGGTGCCCTATGTCTCCTGAATTTTA CCGGGAATATGTGGCAATCAAAACCAAGAAACGAATCTTGCTGTACACCATGAACCCCAA CAAATTTAGAGCTTGCCAGTTTCTGATCAAGTTTCATGAAAGGAGGAATGACAAGATTAT TGTCTTTGCTGACAATGTGTTTGCCCTAAAGGAATATGCCATTCGACTGAACAAACCCTA TATCTACGGACCTACGTCTCAGGGGGAAAGGATGCAAATTCTCCAGAATTTCAAGCACAA CCCCAAAATTAACACCATCTTCATATCCAAGGTAGGTGACACTTCGTTTGATCTGCCGGA AGCAAATGTCCTCATTCAGATCTCATCCCATGGTGGCTCCAGGCGTCAGGAAGCCCAAAG GCTAGGGCGGGTGCTTCGAGCTAAAAAAGGGATGGTTGCAGAAGAGTACAATGCCTTTTT CTACTCACTGGTATCCCAGGACACACAGGAAATGGCTTACTCAACCAAGCGGCAGAGATT CTTGGTAGATCAAGGTTATAGCTTCAAGGTGATCACGAAACTCGCTGGCATGGAGGAGGA AGACTTGGCGTTTTCGACAAAAGAAGAGCAACAGCAGCTCTTACAGAAAGTCCTGGCAGC CACTGACCTGGATGCCGAGGAGGAGGTGGTGGCTGGGGAATTTGGCTCCAGATCCAGCCA GGCATCTCGGCGCTTTGGCACCATGAGTTCTATGTCTGGGGCCGACGACACTGTGTACAT GGAGTACCACTCATCGCGGAGCAAGGCGCCCAGCAAACATGTACACCCGCTCTTCAAGCG CTTTAGGAAATGATGCTTAGGCAGGGTACTTCGTTCAAGACCGGCGCTTGGCACCCTTGT TGGAAAGGGATTTTCAGCATAACATTTTCCTTCCACCTCTTTGACCTTCCCTCCAGCGTT GGCCAAATTGTGCTGAGGAAGATGCATCAAGGGCTTGGCTGTGCCTTCATAGGTCATCTA GGGTTTTATAAAGGAGGAGGAGACAATATTTTTTCAAACTTTTTGGGGAGTGGGGTCATT TCTGTATATAAAAAATGTTAATATTTAAGGTGTATTTATGTTACCGTTCTGAATAAACAG AATGGACCATTGAAAAAAAAAAAAAAAAAAAAAAAAAAA |
Restriction Sites | Please inquire |
ACCN | NM_000122 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_000122.1, NP_000113.1 |
RefSeq Size | 2751 bp |
RefSeq ORF | 2349 bp |
Locus ID | 2071 |
UniProt ID | P19447 |
Domains | DEAD, helicase_C |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Nucleotide excision repair |
Gene Summary | This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] Transcript Variant: This variant (1) represents the shortest transcript and encodes the longer isoform (a). |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC202425 | ERCC3 (Myc-DDK-tagged)-Human excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3) |
CNY 5,728.00 |
|
RC202425L1 | Lenti ORF clone of Human excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3), Myc-DDK-tagged |
CNY 8,128.00 |
|
RC202425L2 | Lenti ORF clone of Human excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3), mGFP tagged |
CNY 7,700.00 |
|
RC202425L3 | Lenti ORF clone of Human excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3), Myc-DDK-tagged |
CNY 7,700.00 |
|
RC202425L4 | Lenti ORF clone of Human excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3), mGFP tagged |
CNY 8,128.00 |
|
RG202425 | ERCC3 (tGFP-tagged) - Human excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3) |
CNY 7,328.00 |
|
SC120091 | ERCC3 (untagged)-Human excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3) |
CNY 5,736.00 |