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HIF 2 alpha (EPAS1) (NM_001430) Human Untagged Clone
CAT＃: SC320566
EPAS1 (untagged)-Human endothelial PAS domain protein 1 (EPAS1)
CNY 9,568.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | bHLHe73; ECYT4; HIF2A; HLF; MOP2; PASD2 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_001430.3
CTTTTCCAGGGAAAAAGGAACTTGGGTTCCCTTCTCTCCGTCCTCTTTTCGGGTCTGACA
GCCTCCACCCACTCCTTCCCCGGACCCCGCCTCCGCGCGCAGGTTCCTCCCAGTCACCTT TCTCCACCCCCGCCCCCGCACCTAGCCCGCCGCGCGCCACCTTCCACCTGACTGCGCGGG GCGCTCGGGACCTGCGCGCACCTCGGACCTTCACCACCCGCCCGGGCCGCGGGGAGCGGA CGAGGGCCACAGCCCCCCACCCGCCAGGGAGCCCAGGTGCTCGGCGTCTGAACGTCTCAA AGGGCCACAGCGACAATGACAGCTGACAAGGAGAAGAAAAGGAGTAGCTCGGAGAGGAGG AAGGAGAAGTCCCGGGATGCTGCGCGGTGCCGGCGGAGCAAGGAGACGGAGGTGTTCTAT GAGCTGGCCCATGAGCTGCCTCTGCCCCACAGTGTGAGCTCCCATCTGGACAAGGCCTCC ATCATGCGACTGGCAATCAGCTTCCTGCGAACACACAAGCTCCTCTCCTCAGTTTGCTCT GAAAACGAGTCCGAAGCCGAAGCTGACCAGCAGATGGACAACTTGTACCTGAAAGCCTTG GAGGGTTTCATTGCCGTGGTGACCCAAGATGGCGACATGATCTTTCTGTCAGAAAACATC AGCAAGTTCATGGGACTTACACAGGTGGAGCTAACAGGACATAGTATCTTTGACTTCACT CATCCCTGCGACCATGAGGAGATTCGTGAGAACCTGAGTCTCAAAAATGGCTCTGGTTTT GGGAAAAAAAGCAAAGACATGTCCACAGAGCGGGACTTCTTCATGAGGATGAAGTGCACG GTCACCAACAGAGGCCGTACTGTCAACCTCAAGTCAGCCACCTGGAAGGTCTTGCACTGC ACGGGCCAGGTGAAAGTCTACAACAACTGCCCTCCTCACAATAGTCTGTGTGGCTACAAG GAGCCCCTGCTGTCCTGCCTCATCATCATGTGTGAACCAATCCAGCACCCATCCCACATG GACATCCCCCTGGATAGCAAGACCTTCCTGAGCCGCCACAGCATGGACATGAAGTTCACC TACTGTGATGACAGAATCACAGAACTGATTGGTTACCACCCTGAGGAGCTGCTTGGCCGC TCAGCCTATGAATTCTACCATGCGCTAGACTCCGAGAACATGACCAAGAGTCACCAGAAC TTGTGCACCAAGGGTCAGGTAGTAAGTGGCCAGTACCGGATGCTCGCAAAGCATGGGGGC TACGTGTGGCTGGAGACCCAGGGGACGGTCATCTACAACCCTCGCAACCTGCAGCCCCAG TGCATCATGTGTGTCAACTACGTCCTGAGTGAGATTGAGAAGAATGACGTGGTGTTCTCC ATGGACCAGACTGAATCCCTGTTCAAGCCCCACCTGATGGCCATGAACAGCATCTTTGAT AGCAGTGGCAAGGGGGCTGTGTCTGAGAAGAGTAACTTCCTATTCACCAAGCTAAAGGAG GAGCCCGAGGAGCTGGCCCAGCTGGCTCCCACCCCAGGAGACGCCATCATCTCTCTGGAT TTCGGGAATCAGAACTTCGAGGAGTCCTCAGCCTATGGCAAGGCCATCCTGCCCCCGAGC CAGCCATGGGCCACGGAGTTGAGGAGCCACAGCACCCAGAGCGAGGCTGGGAGCCTGCCT GCCTTCACCGTGCCCCAGGCAGCTGCCCCGGGCAGCACCACCCCCAGTGCCACCAGCAGC AGCAGCAGCTGCTCCACGCCCAATAGCCCTGAAGACTATTACACATCTTTGGATAACGAC CTGAAGATTGAAGTGATTGAGAAGCTCTTCGCCATGGACACAGAGGCCAAGGACCAATGC AGTACCCAGACGGATTTCAATGAGCTGGACTTGGAGACACTGGCACCCTATATCCCCATG GACGGGGAAGACTTCCAGCTAAGCCCCATCTGCCCCGAGGAGCGGCTCTTGGCGGAGAAC CCACAGTCCACCCCCCAGCACTGCTTCAGTGCCATGACAAACATCTTCCAGCCACTGGCC CCTGTAGCCCCGCACAGTCCCTTCCTCCTGGACAAGTTTCAGCAGCAGCTGGAGAGCAAG AAGACAGAGCCCGAGCACCGGCCCATGTCCTCCATCTTCTTTGATGCCGGAAGCAAAGCA TCCCTGCCACCGTGCTGTGGCCAGGCCAGCACCCCTCTCTCTTCCATGGGGGGCAGATCC AATACCCAGTGGCCCCCAGATCCACCATTACATTTTGGGCCCACAAAGTGGGCCGTCGGG GATCAGCGCACAGAGTTCTTGGGAGCAGCGCCGTTGGGGCCCCCTGTCTCTCCACCCCAT GTCTCCACCTTCAAGACAAGGTCTGCAAAGGGTTTTGGGGCTCGAGGCCCAGACGTGCTG AGTCCGGCCATGGTAGCCCTCTCCAACAAGCTGAAGCTGAAGCGACAGCTGGAGTATGAA GAGCAAGCCTTCCAGGACCTGAGCGGGGGGGACCCACCTGGTGGCAGCACCTCACATTTG ATGTGGAAACGGATGAAGAACCTCAGGGGTGGGAGCTGCCCTTTGATGCCGGACAAGCCA CTGAGCGCAAATGTACCCAATGATAAGTTCACCCAAAACCCCATGAGGGGCCTGGGCCAT CCCCTGAGACATCTGCCGCTGCCACAGCCTCCATCTGCCATCAGTCCCGGGGAGAACAGC AAGAGCAGGTTCCCCCCACAGTGCTACGCCACCCAGTACCAGGACTACAGCCTGTCGTCA GCCCACAAGGTGTCAGGCATGGCAAGCCGGCTGCTCGGGCCCTCATTTGAGTCCTACCTG CTGCCCGAACTGACCAGATATGACTGTGAGGTGAACGTGCCCGTGCTGGGAAGCTCCACG CTCCTGCAAGGAGGGGACCTCCTCAGAGCCCTGGACCAGGCCACCTGAGCCAGGCCTTCT ACCTGGGCAGCACCTCTGCCGACGCCGTCCCACCAGCTTCACTCTCTCCGTCTGTTTTTG CAACTAGGTATTTCTAACGCCAGCACACTATTTACAAGATGGACTTACCTGGCAGACTTG CCCAGGTCACCAAGCAGTGGCCTTTTTCTGAGATGCTCACTTTATTATCCCTATTTTTAA AGTACACAATTGTTTTACCTGTTCTGAAATGTTCTTAAATTTTGTAGGATTTTTTTCCTC CCCACCTTCAATGACTTCTAATTTATATTATCCATAGGTTTCTCTCCCTCCTTCTCCTTC TCACACACAACTGTCCATACTAACAAGTTTGGTGCATGTCTGTTCTTCTGTAGGGAGAAG CTTTAGCTTCATTTTACTAAAAAGATTCCTCGTTATTGTTGTTGCCAAAGAGAAACAAAA ATGATTTTGCTTTCCAAGCTTGGTTTGTGGCGTCTCCCTCGCAGAGCCCTTCTCGTTTCT TTTTTAAACTAATCACCATATTGTAAATTTCAGGGTTTTTTTTTTTGTTTAAGCTGACTC TTTGCTCTAATTTTGGAAAAAAAGAAATGTGAAGGGTCAACTCCAACGTATGTGGTTATC TGTGAAAGTTGCACAGCGTGGCTTTTCCTAAACTGGTGTTTTTCCCCCGCATTTGGTGGA TTTTTTATTATTATTCAAAAACATAACTGAGTTTTTTAAAAGAGGAGAAAATTTATATCT GGGTTAAGTGTTTATCATATATATGGGTACTTTGTAATATCTAAAAACTTAGAAACGGAA ATGGAATCCTGCTCACAAAATCACTTTAAGATCTTTTCGAAGCTGTTAATTTTTCTTAGT GTTGTGGACACTGCAGACTTGTCCAGTGCTCCCACGGCCTGTACGGACACTGTGGAAGGC CTCCCTCTGTCGGCTTTTTGCCATCTGTGATATGCCATAGGTGTGACAATCCGAGCAGTG GAGTCATTCAGCGGGAGCACTGCGCGCTATCCCCTCACATTCTCTATGTACTATGTATGT ATGTATTATTATTATTGCTGCCAAGAGGGTCTGATGGCACGTTGTGGGGTCGGGGGGTGG GGCGGGGAAGTGCTCTAACTTTTCTTAAGGTTTTGTTGCTAGCCCTTCAAGTGCACTGAG CTATGTGACTCGGATGGTCTTTCACACGGCACATTTGGACATTTCCAGAACTACCATGAG ATGGTTTAGACGGGAATTCATGCAAATGAGGGGTCAAAAATGGTATAGTGACCCCGTCCA CGTCCTCCAAGCTCACGACCTTGGAGCCCCGTGGAGCTGGACTGAGGAGGAGGCTGCACA GCGGGAGAGCAGCTGGTCCAGACCAGCCCTGCAGCCCCCACTCAGCCGGCAGCCAGATGG CCCCGCAAGGCCTCCAGGGATGGCCCCTAGCCACAGGCCCTGGCTGAGGTCTCTGGGTCG GTCAGTGACATGTAGGTAGGAAGCACTGAAAATAGTGTTCCCAGAGCACTTTGCAACTCC CTGGGTAAGAGGGACGACACCTCTGGTTTTTCAATACCAATTACATGGAACTTTTCTGTA ATGGGTACAATGAAGAAGTTTCTAAAAACACACACAAAGCACATTGGGCCAACTATTTAG TAAGCCCGGATAGACTTATTGCCAAAAACAAAAAATAGCTTTCAAAAGAAATTTAAGTTC TATGAGAAATTCCTTAGTCATGGTGTTGCGTAAATCATATTTTAGCTGCACGGCATTACC CCACACAGGGTGGCAGAACTTGAAGGGTTACTGACGTGTAAATGCTGGTATTTGATTTCC TGTGTGTGTTGCCCTGGCATTAAGGGCATTTTACCCTTGCAGTTTTACTAAAACACTGAA AAATATTCCAAGCTTCATATTAACCCTACCTGTCAACGTAACGATTTCATGAACGTTATT ATATTGTCGAATTCCTACTGACAACATTATAACTGTATGGGAGCTTAACTTTATAAGGAA ATGTATTTTGACACTGGTATCTTATTAAAGTATTCTGATCCTAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001430 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001430.3, NP_001421.2 |
| RefSeq Size | 5186 bp |
| RefSeq ORF | 2613 bp |
| Locus ID | 2034 |
| UniProt ID | Q99814 |
| Domains | PAS, HLH, PAC |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Pathways in cancer, Renal cell carcinoma |
| Gene Summary | This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208604 | EPAS1 (Myc-DDK-tagged)-Human endothelial PAS domain protein 1 (EPAS1) |
CNY 9,560.00 |
|
| RC208604L1 | Lenti ORF clone of Human endothelial PAS domain protein 1 (EPAS1), Myc-DDK-tagged |
CNY 11,960.00 |
|
| RC208604L2 | Lenti ORF clone of Human endothelial PAS domain protein 1 (EPAS1), mGFP tagged |
CNY 5,890.00 |
|
| RC208604L3 | Lenti ORF clone of Human endothelial PAS domain protein 1 (EPAS1), Myc-DDK-tagged |
CNY 11,960.00 |
|
| RC208604L4 | Lenti ORF clone of Human endothelial PAS domain protein 1 (EPAS1), mGFP tagged |
CNY 11,960.00 |
|
| RG208604 | EPAS1 (tGFP-tagged) - Human endothelial PAS domain protein 1 (EPAS1) |
CNY 11,160.00 |
|
| SC110883 | EPAS1 (untagged)-Human endothelial PAS domain protein 1 (EPAS1) |
CNY 9,568.00 |
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