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GGCX (NM_000821) Human Untagged Clone
CAT＃: SC320393
GGCX (untagged)-Human gamma-glutamyl carboxylase (GGCX), transcript variant 1
CNY 5,560.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | VKCFD1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_000821.3
GTGACCCACCTGCCTCCTCCGCAGAGCAATGGCGGTGTCTGCCGGGTCCGCGCGGACCTC
GCCCAGCTCAGATAAAGTACAGAAAGACAAGGCTGAACTGATCTCAGGGCCCAGGCAGGA CAGCCGAATAGGGAAACTCTTGGGTTTTGAGTGGACAGATTTGTCCAGTTGGCGGAGGCT GGTGACCCTGCTGAATCGACCAACGGACCCTGCAAGCTTAGCTGTCTTTCGTTTTCTTTT TGGGTTCTTGATGGTGCTAGACATTCCCCAGGAGCGGGGGCTCAGCTCTCTGGACCGGAA ATACCTTGATGGGCTGGATGTGTGCCGCTTCCCCTTGCTGGATGCCCTACGCCCACTGCC ACTTGACTGGATGTATCTTGTCTACACCATCATGTTTCTGGGGGCACTGGGCATGATGCT GGGCCTGTGCTACCGGATAAGCTGTGTGTTATTCCTGCTGCCATACTGGTATGTGTTTCT CCTGGACAAGACATCATGGAACAACCACTCCTATCTGTATGGGTTGTTGGCCTTTCAGCT AACATTCATGGATGCAAACCACTACTGGTCTGTGGACGGTCTGCTGAATGCCCATAGGAG GAATGCCCACGTGCCCCTTTGGAACTATGCAGTGCTCCGTGGCCAGATCTTCATTGTGTA CTTCATTGCGGGTGTGAAAAAGCTGGATGCAGACTGGGTTGAAGGCTATTCCATGGAATA TTTGTCCCGGCACTGGCTCTTCAGTCCCTTCAAACTGCTGTTGTCTGAGGAGCTGACTAG CCTGCTGGTCGTGCACTGGGGTGGGCTGCTGCTTGACCTCTCAGCTGGTTTCCTGCTCTT TTTTGATGTCTCAAGATCCATTGGCCTGTTCTTTGTGTCCTACTTCCACTGCATGAATTC CCAGCTTTTCAGCATTGGTATGTTCTCCTACGTCATGCTGGCCAGCAGCCCTCTCTTCTG CTCCCCTGAGTGGCCTCGGAAGCTGGTGTCCTACTGCCCCCGAAGGTTGCAACAACTGTT GCCCCTCAAGGCAGCCCCTCAGCCCAGTGTTTCCTGTGTGTATAAGAGGAGCCGGGGCAA AAGTGGCCAGAAGCCAGGGCTGCGCCATCAGCTGGGAGCTGCCTTCACCCTGCTCTACCT CCTGGAGCAGCTATTCCTGCCCTATTCTCATTTTCTCACCCAGGGCTATAACAACTGGAC AAATGGGCTGTATGGCTATTCCTGGGACATGATGGTGCACTCCCGCTCCCACCAGCACGT GAAGATCACCTACCGTGATGGCCGCACTGGCGAACTGGGCTACCTTAACCCTGGGGTATT TACACAGAGTCGGCGATGGAAGGATCATGCAGACATGCTGAAGCAATATGCCACTTGCCT GAGCCGCCTGCTTCCCAAGTATAATGTCACTGAGCCCCAGATCTACTTTGATATTTGGGT CTCCATCAATGACCGCTTCCAGCAGAGGATTTTTGACCCTCGTGTGGACATCGTGCAGGC CGCTTGGTCACCCTTTCAGCGCACATCCTGGGTGCAACCACTCTTGATGGACCTGTCTCC CTGGAGGGCCAAGTTACAGGAAATCAAGAGCAGCCTAGACAACCACACTGAGGTGGTCTT CATTGCAGATTTCCCTGGACTGCACTTGGAGAATTTTGTGAGTGAAGACCTGGGCAACAC TAGCATCCAGCTGCTGCAGGGGGAAGTGACTGTGGAGCTTGTGGCAGAACAGAAGAACCA GACTCTTCGAGAGGGAGAAAAAATGCAGTTGCCTGCTGGTGAGTACCATAAGGTGTATAC GACATCACCTAGCCCTTCTTGCTACATGTACGTCTATGTCAACACTACAGAGCTTGCACT GGAGCAAGACCTGGCATATCTGCAAGAATTAAAGGAAAAGGTGGAGAATGGAAGTGAAAC AGGGCCTCTACCCCCAGAGCTGCAGCCTCTGTTGGAAGGGGAAGTAAAAGGGGGCCCTGA GCCAACACCTCTGGTTCAGACCTTTCTTAGACGCCAACAAAGGCTCCAGGAGATTGAACG CCGGCGAAATACTCCTTTCCATGAGCGATTCTTCCGCTTCTTGTTGCGAAAGCTCTATGT CTTTCGCCGCAGCTTCCTGATGACTTGTATCTCACTTCGAAATCTGATATTAGGCCGTCC TTCCCTGGAGCAGCTGGCCCAGGAGGTGACTTATGCAAACTTGAGACCCTTTGAGGCAGT TGGAGAACTGAATCCCTCAAACACGGATTCTTCACATTCTAATCCTCCTGAGTCAAATCC TGATCCTGTCCACTCAGAGTTCTGAAGGGGGCCAGATGTTGGGTGCAGATGTAGAAGCAG CCAGTCACAGACCCATTCTATGCAATGGACATTTATTTGAAAAAAATTCTCAAAAGTTTT TTTTTTTTTTTTGGGGGGGCGGGGTTCTAAAGCTGTTTTTAACTCCGAGATTACAACTTA GAGGAACCAAGGAAATAAAGCAAATAAGATTTAACAACCCAAGATTAAGAGGCCAGGAAG AGGTTAGACGCAATGTGAAACTGTCCTCCTAGGATAAGGTTTAAAGTGGCTTTTTGGGGG CTGGGTGCCGTGGCTCACGCCTGTAATCCCAGCATTTTGGGAGGCTGAGGTGGGCAGATC ACTTGAGGCCAGGAGTTCGAGACCAGCCTGGCCAACATGGCAAAACCCCTTCTCTACTAA AAATACAAAAATTAGCCAGACGTGGTGGTGGGTGCCTGTAATCCAACTACCCAGGAGGCT GAGGCATGAGAATCGCTTGGGCCCAGGAGGTGGAGGTTGCAGTGAGCCGAGATCGAGCCA CTGCACTCCTGGGCAACAGAGCAAGACTTCGTCTCAAAATAAATAAATAAAGTGGCTCTT GGGGAAAAGCAATTTAATGTACCACGATGAATAGCTAACTGTTCCCAAGTGTTTGCTATG TGCAACACACCGCGTGAGCAGTGTTACCTGCATTATTACATTAGGCTGAGAGGTAAAATA ATTTGCCCGAAGACATACAGCTAGTGACGAATGGACTGATGGTTTGAACTTAACGTCTAT TTGACTTAAGGTCCTGCACCCTGCCACTTGTAATTTTCAGAATCACTGATAATCTGAAAT AATGCAGCTTAAAACATGTTTTCTTAATTAAAAGTATAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_000821 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000821.3, NP_000812.2 |
| RefSeq Size | 3236 bp |
| RefSeq ORF | 2277 bp |
| Locus ID | 2677 |
| UniProt ID | P38435 |
| Domains | VKG_Carbox |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204003 | GGCX (Myc-DDK-tagged)-Human gamma-glutamyl carboxylase (GGCX), transcript variant 1 |
CNY 5,552.00 |
|
| RC204003L3 | Lenti ORF clone of Human gamma-glutamyl carboxylase (GGCX), transcript variant 1, Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC204003L4 | Lenti ORF clone of Human gamma-glutamyl carboxylase (GGCX), transcript variant 1, mGFP tagged |
CNY 7,700.00 |
|
| RG204003 | GGCX (tGFP-tagged) - Human gamma-glutamyl carboxylase (GGCX), transcript variant 1 |
CNY 7,152.00 |
|
| SC119634 | GGCX (untagged)-Human gamma-glutamyl carboxylase (GGCX), transcript variant 1 |
CNY 5,560.00 |
