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MUM1 (IRF4) (NM_002460) Human Untagged Clone
CAT＃: SC319658
IRF4 (untagged)-Human interferon regulatory factor 4 (IRF4), transcript variant 1
CNY 5,488.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LSIRF; MUM1; NF-EM5; SHEP8 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_002460.1
CTCCGAGTCCAGGGCGAGTGCAGAGCAGAGCGGGCGGAGGACCCCGGGCGCGGGCGCGGA
CGGCACGCGGGGCATGAACCTGGAGGGCGGCGGCCGAGGCGGAGAGTTCGGCATGAGCGC GGTGAGCTGCGGCAACGGGAAGCTCCGCCAGTGGCTGATCGACCAGATCGACAGCGGCAA GTACCCCGGGCTGGTGTGGGAGAACGAGGAGAAGAGCATCTTCCGCATCCCCTGGAAGCA CGCGGGCAAGCAGGACTACAACCGCGAGGAGGACGCCGCGCTCTTCAAGGCTTGGGCACT GTTTAAAGGAAAGTTCCGAGAAGGCATCGACAAGCCGGACCCTCCCACCTGGAAGACGCG CCTGCGGTGCGCTTTGAACAAGAGCAATGACTTTGAGGAACTGGTTGAGCGGAGCCAGCT GGACATCTCAGACCCGTACAAAGTGTACAGGATTGTTCCTGAGGGAGCCAAAAAAGGAGC CAAGCAGCTCACCTTGGAGGACCCGCAGATGTCCATGAGCCACCCCTACACCATGACAAC GCCTTACCCTTCGCTCCCAGCCCAGCAGGTTCACAACTACATGATGCCACCCCTCGACCG AAGCTGGAGGGACTACGTCCCGGATCAGCCACACCCGGAAATCCCGTACCAATGTCCCAT GACGTTTGGACCCCGCGGCCACCACTGGCAAGGCCCAGCTTGTGAAAATGGTTGCCAGGT GACAGGAACCTTTTATGCTTGTGCCCCACCTGAGTCCCAGGCTCCCGGAGTCCCCACAGA GCCAAGCATAAGGTCTGCCGAAGCCTTGGCGTTCTCAGACTGCCGGCTGCACATCTGCCT GTACTACCGGGAAATCCTCGTGAAGGAGCTGACCACGTCCAGCCCCGAGGGCTGCCGGAT CTCCCATGGACATACGTATGACGCCAGCAACCTGGACCAGGTCCTGTTCCCCTACCCAGA GGACAATGGCCAGAGGAAAAACATTGAGAAGCTGCTGAGCCACCTGGAGAGGGGCGTGGT CCTCTGGATGGCCCCCGACGGGCTCTATGCGAAAAGACTGTGCCAGAGCAGGATCTACTG GGACGGGCCCCTGGCGCTGTGCAACGACCGGCCCAACAAACTGGAGAGAGACCAGACCTG CAAGCTCTTTGACACACAGCAGTTCTTGTCAGAGCTGCAAGCGTTTGCTCACCACGGCCG CTCCCTGCCAAGATTCCAGGTGACTCTATGCTTTGGAGAGGAGTTTCCAGACCCTCAGAG GCAAAGAAAGCTCATCACAGCTCACGTAGAACCTCTGCTAGCCAGACAACTATATTATTT TGCTCAACAAAACAGTGGACATTTCCTGAGGGGCTACGATTTACCAGAACACATCAGCAA TCCAGAAGATTACCACAGATCTATCCGCCATTCCTCTATTCAAGAATGAAAAATGTCAAG ATGAGTGGTTTTCTTTTTCCTTTTTTTTTTTTTTTTGATACGGAGATACGGGGTCTTGCT CTGTCTCCCAGGCTGGAGTGCAGTGACACAATCTCAGCTCACTGTGACCTCCGCCTCCTG GGTTCAAGAGACTCTCCTGCCTCAGCCTCCCTGGTAGCTGGGATTACAGGTGTGAGCCAC TGCACCCACCCAAGACAAGTGATTTTCATTGTAAATATTTGACTTTAGTGAAAGCGTCCA ATTGACTGCCCTCTTACTGTTTTGAGGAACTCAGAAGTGGAGATTTCAGTTCAGCGGTTG AGGAGAATTGCGGCGAGACAAGCATGGAAAATCAGTGACATCTGATTGGCAGATGAGCTT ATTTCAAAAGGAAGGGTGGCTTTGCATTTCTTGTGTTCTATAGACTGCCATCATTGATGA TCACTGTGAAAATTGACCAAGTGATGTGTTTACATTTACTGAAATGCGCTCTTTAATTTG TTGTAGATTAGGTCTTGCTGGAAGACAGAGAAAACTTGCCTTTCAGTATTGACACTGACT AGAGTGATGACTGCTTGTAGGTATGTCTGTGCCATTTCTCAGGGAAGTAAGATGTAAATT GAAGAAGCCTCACACGTAAAAGAAATGTATTAACGTATGTAGGAGCTGCAGTTCTTGTGG AAGACACTTGCTGAGTGAAGGAAATGAATCTTTGACTGAAGCCGTGCCTGTAGCCTTGGG GAGGCCCATCCCCCACCTGCCAGCGGTTTCCTGGTGTGGGTCCCTCTGCTCCCTCTGAAA AAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_002460 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002460.1, NP_002451.1 |
| RefSeq Size | 5065 bp |
| RefSeq ORF | 1356 bp |
| Locus ID | 3662 |
| UniProt ID | Q15306 |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010] Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Role of IRF4 in IFN-Stimulated Gene Induction and Maintenance of Kaposi Sarcoma–Associated Herpesvirus Latency in Primary Effusion Lymphoma Cells
,Adriana Forero, Patrick S. Moore, and Saumendra N. Sarkar,
J. Immunol., Aug 2013; 191: 1476 - 1485.
,PubMed ID 23804715
[IRF4]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204876 | IRF4 (Myc-DDK-tagged)-Human interferon regulatory factor 4 (IRF4), transcript variant 1 |
CNY 5,488.00 |
|
| RC204876L1 | Lenti ORF clone of Human interferon regulatory factor 4 (IRF4), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC204876L2 | Lenti ORF clone of Human interferon regulatory factor 4 (IRF4), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
| RC204876L3 | Lenti ORF clone of Human interferon regulatory factor 4 (IRF4), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC204876L4 | Lenti ORF clone of Human interferon regulatory factor 4 (IRF4), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
| RG204876 | IRF4 (tGFP-tagged) - Human interferon regulatory factor 4 (IRF4), transcript variant 1 |
CNY 7,088.00 |
