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MDS028 (ITFG2) (NM_018463) Human Untagged Clone
CAT＃: SC319346
ITFG2 (untagged)-Human integrin alpha FG-GAP repeat containing 2 (ITFG2)
CNY 3,656.00
CNY 7,220.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FGGAP1; MDS028 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_018463.2
CGCTCCCTCTGCTCTTGGAGGTGCCATGAGGTCAGTTAGCTACGTGCAGCGCGTGGCGCT
GGAGTTCAGCGGGAGCCTCTTCCCGCACGCAATCTGCCTCGGAGACGTTGATAACGATAC GTTAAATGAACTGGTGGTGGGAGACACCAGCGGGAAGGTGTCTGTGTATAAAAATGATGA CAGTCGGCCATGGCTCACCTGTTCCTGCCAGGGAATGCTGACTTGCGTTGGGGTTGGAGA CGTGTGTAATAAAGGAAAGAACCTGTTGGTGGCAGTGAGTGCTGAAGGCTGGTTTCATTT GTTTGACCTGACACCTGCCAAGGTGTTGGATGCTTCTGGGCACCACGAGACACTAATCGG AGAGGAGCAGCGTCCAGTCTTCAAGCAGCACATCCCTGCCAACACCAAGGTCATGCTGAT CAGCGACATCGATGGAGATGGGTGTCGTGAGCTGGTGGTGGGCTACACAGACCGTGTGGT GCGAGCTTTCCGCTGGGAGGAGCTAGGTGAGGGTCCTGAACATCTGACAGGGCAGCTGGT GTCCCTCAAGAAATGGATGCTGGAGGGTCAGGTGGACAGCCTCTCAGTGACTCTGGGGCC ACTGGGTCTTCCTGAACTGATGGTGTCTCAGCCAGGTTGTGCGTATGCAATTCTACTGTG TACCTGGAAAAAGGACACTGGGTCCCCTCCTGCCTCTGAAGGGCCCACGGATGGTAGTAG GGAGACCCCAGCTGCCCGAGACGTGGTGCTGCACCAGACATCTGGCCGTATCCACAACAA GAATGTCTCCACTCACCTAATTGGCAACATCAAACAAGGCCACGGCACTGAGAGTAGTGG CTCTGGCCTCTTTGCCCTGTGCACCCTGGATGGGACACTGAAGCTCATGGAAGAAATGGA AGAAGCAGACAAGCTGCTGTGGTCAGTGCAGGTGGATCACCAGCTCTTTGCCCTGGAGAA ACTGGATGTCACCGGCAACGGGCATGAGGAGGTAGTTGCATGCGCCTGGGATGGACAGAC ATATATCATTGATCACAACCGCACCGTCGTCCGCTTCCAAGTGGATGAAAATATCCGTGC CTTCTGTGCAGGCCTGTACGCCTGCAAAGAGGGCCGCAACAGCCCCTGCCTCGTATATGT CACTTTCAACCAGAAGATCTATGTGTACTGGGAGGTGCAGCTGGAGCGGATGGAGTCTAC CAATCTGGTGAAACTGCTGGAGACCAAGCCGGAGTACCACAGCCTGCTGCAGGAGCTGGG CGTGGATCCTGACGACCTCCCTGTGACTCGTGCCCTGCTTCACCAAACGCTCTACCATCC AGACCAGCCACCACAGTGTGCTCCCTCAAGCCTCCAGGATCCCACCTAGCTGTACTTGCC TCATAGCTGGTGAAGGATTCTTCTGAACCCCCACCCTACCCCCTAAAGGTATCTGTGGTA TTGGCAGGATAGGGAATATGCATTACAGAAATGCAGGATTTGACTCTGGGCATGAAAGAT GGCAGCAGCCCTAGGGTGACCGTGAACTATAGACCTCGCAGTCTTTTCGGTGAAAGAAGA GACAAGTTGACCCTCTGCCCATTTCCTTATGGACCTCACCCATCATGCCAGCAGGGTCAT AGGACCCTGGCCTTGTTCCAAATCATCTGGGACATGACCCACTCCCCACTGTCACTGTGT TGAAAACAGAGACTTGTTTGTGTGGCCCCAACACCCATAAGGAAACCAGGCTTTAGGCCC AGGGGAGCAGTGGAGGTAAGGGCTCCACCCCATCTTAAGCTCTGTCTTCCGTGGCACAAT TCCAAGTTCTTGACGTTAGTAATTGTTAAAGGAATGGCAAACTGTAAAAAAAAAAAAAAA AAA |
| Restriction Sites | Please inquire |
| ACCN | NM_018463 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_018463.2, NP_060933.2 |
| RefSeq Size | 2155 bp |
| RefSeq ORF | 1344 bp |
| Locus ID | 55846 |
| UniProt ID | Q969R8 |
| Domains | FG-GAP |
| Protein Families | Druggable Genome |
| Gene Summary | As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes a functional protein. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200818 | ITFG2 (Myc-DDK-tagged)-Human integrin alpha FG-GAP repeat containing 2 (ITFG2) |
CNY 3,656.00 |
|
| RC200818L3 | Lenti ORF clone of Human integrin alpha FG-GAP repeat containing 2 (ITFG2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200818L4 | Lenti ORF clone of Human integrin alpha FG-GAP repeat containing 2 (ITFG2), mGFP tagged |
CNY 5,890.00 |
|
| RG200818 | ITFG2 (tGFP-tagged) - Human integrin alpha FG-GAP repeat containing 2 (ITFG2) |
CNY 5,256.00 |
