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SH3BP2 (NM_001122681) Human Untagged Clone
CAT＃: SC318934
SH3BP2 (untagged)-Human SH3-domain binding protein 2 (SH3BP2), transcript variant 2
CNY 6,270.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 3BP-2; 3BP2; CRBM; CRPM; RES4-23 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC318934 representing NM_001122681.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCGGCTGAAGAGATGCATTGGCCTGTCCCTATGAAGGCCATTGGTGCCCAGAACCTGCTAACCATG CCTGGGGGCGTGGCCAAGGCTGGCTACCTGCACAAGAAGGGCGGTACCCAGCTGCAGCTGCTGAAATGG CCCCTGCGCTTTGTCATCATCCACAAACGCTGCGTCTACTACTTCAAGAGTAGCACCTCTGCCTCCCCG CAGGGCGCCTTCTCCCTGAGTGGCTATAACCGGGTGATGCGGGCGGCTGAGGAGACCACGTCCAACAAC GTTTTCCCCTTCAAGATCATCCATATCAGCAAGAAGCACCGCACGTGGTTCTTCTCGGCCTCCTCCGAG GAGGAGCGCAAGAGCTGGATGGCCTTGCTGCGCAGGGAGATTGGCCACTTCCACGAAAAGAAAGACCTG CCCTTGGACACCAGCGACTCCAGCTCGGACACAGACAGCTTCTACGGCGCAGTTGAGCGGCCTGTGGAT ATCAGCCTTTCCCCGTACCCCACGGACAATGAAGACTATGAGCACGACGATGAGGATGACTCCTACCTG GAGCCTGACTCCCCGGAGCCCGGAAGGCTTGAGGATGCCCTGATGCACCCACCGGCTTACCCACCACCC CCAGTGCCCACGCCCAGGAAGCCAGCCTTCTCTGACATGCCCCGGGCCCACTCCTTTACCTCCAAGGGC CCCGGTCCCCTACTGCCACCCCCGCCCCCTAAGCACGGCCTCCCAGATGTTGGCCTGGCTGCTGAGGAC TCCAAGAGGGACCCACTGTGCCCGAGGCGGGCTGAGCCTTGCCCCAGGGTACCTGCTACCCCCCGAAGG ATGAGCGATCCCCCTCTGAGCACCATGCCCACCGCACCCGGCCTCCGGAAACCCCCTTGCTTCCGGGAG AGTGCCAGCCCCAGCCCGGAGCCCTGGACCCCTGGCCACGGGGCCTGCTCCACTTCCAGTGCTGCCATC ATGGCCACTGCCACCTCCAGAAACTGTGACAAACTCAAGTCCTTCCACCTGTCCCCCCGAGGACCACCC ACATCTGAGCCCCCACCTGTGCCAGCCAACAAGCCCAAGTTCCTGAAGATAGCTGAAGAGGACCCCCCA AGGGAGGCAGCCATGCCCGGACTCTTTGTGCCCCCCGTGGCTCCCCGGCCTCCTGCGCTGAAGCTGCCA GTGCCTGAGGCCATGGCGCGGCCCGCAGTCCTGCCCAGGCCAGAGAAGCCGCAGCTCCCGCACCTCCAG CGATCACCCCCCGATGGGCAGAGTTTCAGGAGCTTCTCCTTTGAAAAGCCCCGGCAACCCTCACAGGCT GACACTGGCGGGGACGACTCGGACGAGGACTATGAGAAGGTGCCACTGCCCAACTCGGTCTTCGTCAAC ACCACGGAGTCCTGCGAAGTGGAAAGGTTGTTCAAGGCTACAAGCCCCCGGGGAGAGCCCCAGGATGGA CTCTACTGCATCCGGAACTCCTCTACCAAGTCGGGGAAGGTCCTGGTTGTGTGGGACGAAACCTCTAAC AAAGTGAGGAACTATCGCATTTTTGAGAAGGACTCTAAGTTCTACCTGGAGGGCGAGGTCCTGTTTGTG AGTGTGGGCAGCATGGTGGAGCACTACCACACCCACGTGCTGCCCAGCCACCAGAGCCTGCTGCTGCGG CACCCCTACGGCTACACTGGGCCTAGGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001122681 |
| Insert Size | 1686 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001122681.1 |
| RefSeq Size | 9068 bp |
| RefSeq ORF | 1686 bp |
| Locus ID | 6452 |
| UniProt ID | P78314 |
| Protein Families | Druggable Genome |
| Protein Pathways | Natural killer cell mediated cytotoxicity |
| MW | 62.2 kDa |
| Gene Summary | The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] Transcript Variant: This variant (2) represents use of an alternative promoter and 5' UTR and uses a downstream translation start site, compared to variant 3. The resulting isoform (a) has a shorter N-terminus, compared to isoform b. Variants 1 and 2 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC225960 | SH3BP2 (Myc-DDK-tagged)-Human SH3-domain binding protein 2 (SH3BP2), transcript variant 2 |
CNY 4,176.00 |
|
| RC225960L1 | Lenti ORF clone of Human SH3-domain binding protein 2 (SH3BP2), transcript variant 2, Myc-DDK-tagged |
CNY 6,576.00 |
|
| RC225960L2 | Lenti ORF clone of Human SH3-domain binding protein 2 (SH3BP2), transcript variant 2, mGFP tagged |
CNY 6,460.00 |
|
| RC225960L3 | Lenti ORF clone of Human SH3-domain binding protein 2 (SH3BP2), transcript variant 2, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC225960L4 | Lenti ORF clone of Human SH3-domain binding protein 2 (SH3BP2), transcript variant 2, mGFP tagged |
CNY 6,460.00 |
|
| RG225960 | SH3BP2 (tGFP-tagged) - Human SH3-domain binding protein 2 (SH3BP2), transcript variant 2 |
CNY 5,040.00 |
