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USP6 (NM_004505) Human Untagged Clone
CAT＃: SC318613
USP6 (untagged)-Human ubiquitin specific peptidase 6 (Tre-2 oncogene) (USP6)
CNY 27,080.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HRP1; Tre-2; TRE2; TRE17; TRESMCR; USP6-short |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC318613 representing NM_004505.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGACATGGTAGAGAATGCAGATAGTTTGCAGGCACAGGAGCGGAAGGACATACTTATGAAGTATGAC AAGGGACACCGAGCTGGGCTGCCAGAGGACAAGGGGCCTGAGCCCGTTGGAATCAACAGCAGCATTGAT CGTTTTGGCATTTTGCATGAGACGGAGCTGCCTCCTGTGACTGCACGGGAGGCGAAGAAAATTCGGCGG GAGATGACACGAACGAGCAAGTGGATGGAAATGCTGGGAGAATGGGAGACATATAAGCACAGTAGCAAA CTCATAGATCGAGTGTACAAGGGAATTCCCATGAACATCCGGGGCCCGGTGTGGTCAGTCCTCCTGAAC ATTCAGGAAATCAAGTTGAAAAACCCCGGAAGATACCAGATCATGAAGGAGAGGGGCAAGAGGTCATCT GAACACATCCACCACATCGACCTGGACGTGAGGACGACTCTCCGGAACCATGTCTTCTTTAGGGATCGA TATGGAGCCAAGCAGAGGGAACTATTCTACATCCTCCTGGCCTATTCGGAGTATAACCCGGAGGTGGGC TACTGCAGGGACCTGAGCCACATCACCGCCTTGTTCCTCCTTTATCTGCCTGAGGAGGACGCATTCTGG GCACTGGTGCAGCTGCTGGCCAGTGAGAGGCACTCCCTGCCAGGATTCCACAGCCCAAATGGTGGGACA GTCCAGGGGCTCCAAGACCAACAGGAGCATGTGGTACCCAAGTCACAACCCAAGACCATGTGGCATCAG GACAAGGAAGGTCTATGCGGGCAGTGTGCCTCGTTAGGCTGCCTTCTCCGGAACCTGATTGACGGGATC TCTCTCGGGCTCACCCTGCGCCTGTGGGACGTGTATTTGGTGGAAGGAGAACAGGTGTTGATGCCAATA ACCAGCATTGCTCTTAAGGTTCAGCAGAAGCGCCTCATGAAGACATCCAGGTGTGGCCTGTGGGCACGT CTGCGGAACCAATTCTTCGATACCTGGGCCATGAACGATGACACCGTGCTCAAGCATCTTAGGGCCTCT ACGAAGAAACTAACAAGGAAGCAAGGGGACCTGCCACCCCCAGCCAAACGCGAGCAAGGGTCCTTGGCA CCCAGGCCTGTGCCGGCTTCACGTGGTGGGAAGACCCTCTGCAAGGGGTATAGGCAGGCCCCTCCAGGC CCACCAGCCCAGTTCCAGCGGCCCATTTGCTCAGCTTCCCCGCCATGGGCATCTCGTTTTTCCACGCCC TGTCCTGGTGGGGCTGTCCGGGAAGACACGTACCCTGTGGGCACTCAGGGTGTGCCCAGCCTGGCCCTG GCTCAGGGAGGACCTCAGGGTTCCTGGAGATTCCTGGAGTGGAAGTCAATGCCCCGGCTCCCAACGGAC CTGGATATAGGGGGCCCTTGGTTCCCCCATTATGATTTTGAATGGAGCTGCTGGGTCCGTGCCATATCC CAGGAGGACCAGCTGGCCACCTGCTGGCAGGCTGAACACTGCGGAGAGGTTCACAACAAAGATATGAGT TGGCCTGAGGAGATGTCTTTTACAGCAAATAGTAGTAAAATAGATAGACAAAAGGTTCCCACAGAAAAG GGAGCCACAGGTCTAAGCAACCTGGGAAACACATGCTTCATGAACTCAAGCATCCAGTGCGTTAGTAAC ACACAGCCACTGACACAGTATTTTATCTCAGGGAGACATCTTTATGAACTCAACAGGACAAATCCCATT GGTATGAAGGGGCATATGGCTAAATGCTATGGTGATTTAGTGCAGGAACTCTGGAGTGGAACTCAGAAG AGTGTTGCCCCATTAAAGCTTCGGCGGACCATAGCAAAATATGCTCCCAAGTTTGATGGGTTTCAGCAA CAAGACTCCCAAGAACTTCTGGCTTTTCTCTTGGATGGTCTTCATGAAGATCTCAACCGAGTCCATGAA AAGCCATATGTGGAACTGAAGGACAGTGATGGCCGACCAGACTGGGAAGTAGCTGCAGAGGCCTGGGAC AACCATCTAAGAAGAAATAGATCAATTATTGTGGATTTGTTCCATGGGCAGCTAAGATCTCAAGTCAAA TGCAAGACATGTGGGCATATAAGTGTCCGATTTGACCCTTTCAATTTTTTGTCTTTGCCACTACCAATG GACAGTTACATGGACTTAGAAATAACAGTGATTAAGTTAGATGGTACTACCCCTGTACGGTATGGACTA AGACTGAATATGGATGAAAAGTACACAGGTTTAAAAAAACAGCTGAGGGATCTCTGTGGACTTAATTCA GAACAAATCCTACTAGCAGAAGTACATGATTCCAACATAAAGAACTTTCCTCAGGATAACCAAAAAGTA CAACTCTCAGTGAGCGGATTTTTGTGTGCATTTGAAATTCCTGTCCCTTCATCTCCAATTTCAGCTTCT AGTCCAACACAAATAGATTTCTCCTCTTCACCATCTACAAATGGAATGTTCACCCTAACTACCAATGGG GACCTACCCAAACCAATATTCATCCCCAATGGAATGCCAAACACTGTTGTGCCATGTGGAACTGAGAAG AACTTCACAAATGGAATGGTTAATGGTCACATGCCATCTCTTCCTGACAGCCCCTTTACAGGTTACATC ATTGCAGTCCACCGAAAAATGATGAGGACAGAACTGTATTTCCTGTCACCTCAGGAGAATCGCCCCAGC CTCTTTGGAATGCCATTGATTGTTCCATGCACTGTGCATACCCGGAAGAAAGACCTATATGATGCGGTT TGGATTCAAGTATCCTGGTTAGCAAGACCACTCCCACCTCAGGAAGCTAGTATTCATGCCCAGGATCGT GATAACTGTATGGGCTATCAATATCCATTCACTCTACGAGTTGTGCAGAAAGATGGGAACTCCTGTGCT TGGTGCCCACAGTATAGATTTTGCAGAGGCTGTAAAATTGATTGTGGGGAAGACAGAGCTTTCATTGGA AATGCCTATATTGCTGTGGATTGGCACCCCACAGCCCTTCACCTTCGCTATCAAACATCCCAGGAAAGG GTTGTAGATAAGCATGAGAGTGTGGAGCAGAGTCGGCGAGCGCAAGCCGAGCCCATCAACCTGGACAGC TGTCTCCGTGCTTTCACCAGTGAGGAAGAGCTAGGGGAAAGTGAGATGTACTACTGTTCCAAGTGTAAG ACCCACTGCTTAGCAACAAAGAAGCTGGATCTCTGGAGGCTTCCACCCTTCCTGATTATTCACCTTAAG CGATTTCAATTTGTAAATGATCAGTGGATAAAATCACAGAAAATTGTCAGATTTCTTCGGGAAAGTTTT GATCCGAGTGCTTTTTTGGTACCACGAGACCCGGCCCTCTGCCAGCATAAACCACTCACACCCCAGGGG GATGAGCTCTCCAAGCCCAGGATTCTGGCAAGAGAGGTGAAGAAAGTGGATGCGCAGAGTTCGGCTGGA AAAGAGGACATGCTCCTAAGCAAAAGCCCATCCTCACTCAGCGCTAACATCAGCAGCAGCCCAAAAGGT TCTCCTTCTTCATCAAGAAAAAGTGGAACCAGCTGTCCCTCCAGCAAAAACAGCAGCCCTAATAGCAGC CCACGGACTTTGGGGAGGAGCAAAGGGAGGCTCCGGCTGCCCCAGATTGGCAGCAAAAATAAGCCGTCA AGTAGTAAGAAGAACTTGGATGCCAGCAAAGAGAATGGGGCTGGGCAGATCTGTGAGCTGGCTGACGCC TTGAGCCGAGGGCATATGCGGGGGGGCAGCCAACCAGAGCTGGTCACTCCTCAGGACCATGAGGTAGCT TTGGCCAATGGATTCCTTTATGAGCATGAAGCATGTGGCAATGGCTGTGGCGATGGCTACAGCAATGGT CAGCTTGGAAACCACAGTGAAGAAGACAGCACTGATGACCAAAGAGAAGACACTCATATTAAGCCTATT TATAATCTATATGCAATTTCATGCCATTCAGGAATTCTGAGTGGGGGCCATTACATCACTTATGCCAAA AACCCAAACTGCAAGTGGTACTGTTATAATGACAGCAGCTGTGAGGAACTTCACCCTGATGAAATTGAC ACCGACTCTGCCTACATTCTTTTCTATGAGCAGCAGGGGATAGACTACGCACAATTTCTGCCAAAGATT GATGGCAAAAAGATGGCAGACACAAGCAGTACGGATGAAGACTCTGAGTCTGATTACGAAAAGTACTCT ATGTTACAGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_004505 |
| Insert Size | 4221 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004505.3 |
| RefSeq Size | 7993 bp |
| RefSeq ORF | 4221 bp |
| Locus ID | 9098 |
| UniProt ID | P35125 |
| Protein Families | Druggable Genome, Protease |
| MW | 158.7 kDa |
| Gene Summary | Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215749 | USP6 (Myc-DDK-tagged)-Human ubiquitin specific peptidase 6 (Tre-2 oncogene) (USP6) |
CNY 9,624.00 |
|
| RC215749L1 | Lenti ORF clone of Human ubiquitin specific peptidase 6 (Tre-2 oncogene) (USP6), Myc-DDK-tagged |
CNY 12,024.00 |
|
| RC215749L2 | Lenti ORF clone of Human ubiquitin specific peptidase 6 (Tre-2 oncogene) (USP6), mGFP tagged |
CNY 15,960.00 |
|
| RC215749L3 | Lenti ORF clone of Human ubiquitin specific peptidase 6 (Tre-2 oncogene) (USP6), Myc-DDK-tagged |
CNY 15,960.00 |
|
| RC215749L4 | Lenti ORF clone of Human ubiquitin specific peptidase 6 (Tre-2 oncogene) (USP6), mGFP tagged |
CNY 15,960.00 |
|
| RG215749 | USP6 (tGFP-tagged) - Human ubiquitin specific peptidase 6 (Tre-2 oncogene) (USP6) |
CNY 15,490.00 |
|
| SC318615 | USP6 (untagged)-Human ubiquitin specific peptidase 6 (Tre-2 oncogene) (USP6) |
CNY 27,080.00 |
