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WHIP (WRNIP1) (NM_020135) Human Untagged Clone
CAT＃: SC318132
WRNIP1 (untagged)-Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 1
CNY 10,640.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | bA420G6.2; CFAP93; FAP93; WHIP |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC318132 representing NM_020135.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGAGGTGAGCGGGCCGGAAGACGACCCCTTCCTTTCGCAGCTGCACCAGGTGCAGTGCCCCGTGTGC CAGCAGATGATGCCCGCCGCGCACATCAACTCGCACCTGGACCGCTGTCTGCTGCTCCACCCGGCGGGG CACGCGGAGCCCGCGGCCGGGTCGCACCGCGCCGGGGAGCGGGCCAAGGGGCCCTCGCCGCCCGGCGCC AAGAGGCGGCGGCTGTCGGAGAGCTCGGCGCTGAAGCAGCCAGCCACCCCGACGGCAGCCGAGAGCAGC GAGGGCGAGGGTGAGGAGGGCGACGACGGCGGCGAGACCGAGAGCCGCGAGAGCTACGACGCGCCGCCC ACACCCAGCGGCGCCCGCCTTATCCCCGACTTCCCGGTGGCCCGCTCCAGCAGCCCCGGGAGGAAGGGG TCGGGGAAGAGGCCGGCGGCCGCCGCCGCGGCGGGGAGCGCGTCTCCGCGCAGCTGGGACGAGGCGGAG GCGCAGGAGGAGGAGGAGGCCGTGGGCGACGGCGATGGCGACGGGGACGCGGACGCGGACGGCGAGGAC GACCCGGGGCACTGGGACGCGGACGCTGCCGAAGCCGCCACCGCCTTCGGGGCCAGTGGCGGGGGCCGC CCGCACCCCCGGGCGCTGGCTGCCGAGGAGATCCGACAGATGCTACAGGGCAAGCCGCTGGCCGACACG ATGCGTCCTGACACGCTGCAGGATTACTTCGGGCAGAGCAAGGCCGTGGGCCAGGATACCCTGCTGCGC TCGCTCCTGGAGACCAACGAAATCCCCTCGCTTATCCTGTGGGGGCCGCCGGGCTGCGGCAAGACCACT CTGGCTCACATCATAGCCAGCAACAGCAAGAAACATAGCATAAGGTTTGTGACATTATCTGCAACAAAT GCCAAGACAAATGATGTGCGAGATGTCATAAAACAAGCTCAAAATGAAAAGAGCTTTTTCAAAAGGAAA ACCATCCTTTTTATTGATGAGATTCATCGGTTCAATAAATCTCAGCAGGACACTTTCCTTCCTCACGTG GAATGTGGGACGATCACTCTGATTGGGGCAACCACTGAAAACCCTTCCTTCCAGGTCAACGCTGCTCTT CTGAGCCGCTGTCGAGTGATTGTTCTTGAGAAGCTTCCAGTAGAGGCAATGGTGACTATTTTAATGCGA GCGATCAACTCCCTGGGAATCCACGTCCTAGACTCTAGCCGTCCCACTGACCCTCTGAGCCACAGCAGC AACAGCAGCTCAGAGCCCGCCATGTTCATAGAGGATAAAGCAGTAGACACCCTGGCTTACCTCAGTGAC GGTGACGCCCGAGCTGGGTTGAACGGACTGCAGCTGGCGGTGCTGGCTAGGTTAAGCTCTAGGAAGATG TTCTGTAAGAAGAGTGGGCAATCCTATTCTCCCAGTAGAGTTCTGATCACAGAGAATGACGTGAAGGAG GGCCTACAGCGATCCCACATTTTATATGACCGGGCAGGTGAGGAGCATTACAACTGCATCTCCGCCCTG CACAAGTCCATGCGGGGCTCAGACCAGAACGCCTCCCTCTACTGGCTGGCTCGCATGCTCGAGGGAGGA GAGGACCCACTCTACGTGGCACGGAGGCTTGTCAGGTTTGCCAGCGAGGACATAGGTCTGGCAGACCCG TCTGCGTTAACACAAGCGGTTGCTGCCTACCAAGGCTGTCATTTTATAGGCATGCCTGAATGTGAGGTG CTTCTGGCCCAGTGTGTGGTCTACTTTGCCAGAGCCCCAAAGTCCATTGAGGTGTACAGCGCCTACAAC AACGTCAAAGCCTGCCTGAGGAACCACCAGGGGCCACTGCCCCCCGTGCCCCTGCACCTGAGGAACGCG CCCACTAGGCTGATGAAGGATTTGGGCTATGGCAAAGGCTACAAGTACAACCCCATGTACAGCGAGCCT GTGGATCAGGAGTACCTGCCTGAAGAGTTGAGGGGGGTAGATTTCTTCAAGCAGAGGAGGTGCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_020135 |
| Insert Size | 1998 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_020135.2 |
| RefSeq Size | 2670 bp |
| RefSeq ORF | 1998 bp |
| Locus ID | 56897 |
| UniProt ID | Q96S55 |
| Domains | AAA, AAA, ZnF_Rad18 |
| MW | 72.1 kDa |
| Gene Summary | Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene. [provided by RefSeq, Jul 2012] Transcript Variant: This variant (1) encodes the longer isoform (1). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218585 | WRNIP1 (Myc-DDK-tagged)-Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 1 |
CNY 4,952.00 |
|
| RC218585L3 | Lenti-ORF clone of WRNIP1 (Myc-DDK-tagged)-Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 1 |
CNY 7,700.00 |
|
| RC218585L4 | Lenti-ORF clone of WRNIP1 (mGFP-tagged)-Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 1 |
CNY 7,700.00 |
|
| RG218585 | WRNIP1 (tGFP-tagged) - Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 1 |
CNY 6,552.00 |
|
| SC111831 | WRNIP1 (untagged)-Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 1 |
CNY 6,520.00 |
