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KSR1 (NM_014238) Human Untagged Clone
CAT＃: SC316830
KSR1 (untagged)-Human kinase suppressor of ras 1 (KSR1)
CNY 5,592.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | KSR; RSU2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC316830 sequence for NM_014238 edited (data generated by NextGen Sequencing)
ATGAATGAGGCCAAGGTGAAGGAGACGCTGCGGCGCTGTGGGGCCAGCGGGGATGAGTGTGGCCGTCTGC AGTATGCCCTCACCTGCCTGCGGAAGGTGACAGGCCTGGGAGGGGAGCACAAGGAGGACTCCAGTTGGAG TTCATTGGATGCGCGGCGGGAAAGTGGCTCAGGGCCTTCCACGGACACCCTCTCAGCAGCCAGCCTGCCC TGGCCCCCAGGGAGCTCCCAGCTGGGCAGAGCAGGCAACAGCGCCCAGGGCCCACGCTCCATCTCCGTGT CAGCTCTTCCCGCCTCAGACTCCCCCACCCCCAGCTTCAGTGAGGGCCTCTCAGACACCTGTATTCCCCT GCACGCCAGCGGCCGGCTGACCCCCCGTGCCCTGCACAGCTTCATCACCCCGCCCACCACACCCCAGCTG CGACGGCACACCAAGCTGAAGCCACCACGGACGCCCCCCCCACCCAGCCGCAAGGTCTTCCAGCTGCTGC CCAGCTTCCCCACACTCACCCGGAGCAAGTCCCATGAGTCTCAGCTGGGGAACCGCATTGATGACGTCTC CTCGATGAGGTTTGATCTCTCGCATGGATCCCCACAGATGGTACGGAGGGATATCGGGCTGTCGGTGACG CACAGGTTCTCCACCAAGTCCTGGCTGTCGCAGGTCTGCCACGTGTGCCAGAAGAGCATGATATTTGGAG TGAAGTGCAAGCATTGCAGGTTGAAGTGTCACAACAAATGTACCAAAGAAGCCCCTGCCTGTAGAATATC CTTCCTGCCACTAACTCGGCTTCGGAGGACAGAATCTGTCCCCTCGGACATCAACAACCCGGTGGACAGA GCAGCCGAACCCCATTTTGGAACCCTCCCCAAAGCACTGACAAAGAAGGAGCACCCTCCGGCCATGAATC ACCTGGACTCCAGCAGCAACCCTTCCTCCACCACCTCCTCCACACCCTCCTCACCGGCGCCCTTCCCGAC ATCATCCAACCCATCCAGCGCCACCACGCCCCCCAACCCCTCACCTGGCCAGCGGGACAGCAGGTTCAAC TTCCCAGCTGCCTACTTCATTCATCATAGACAGCAGTTTATCTTTCCAGTGCCATCTGCTGGCCATTGCT GGAAATGCCTCCTTATTGCAGAAAGTTTAAAGGAAAACGCTTTCAACATTTCAGCCTTTGCACACGCAGC CCCGCTCCCTGAAGCTGCCGACGGTACCCGGCTCGATGACCAGCCGAAAGCAGATGTGTTGGAAGCTCAC GAAGCGGAGGCTGAGGAGCCAGAGGCTGGCAAGTCAGAGGCAGAAGACGATGAGGACGAGGTGGACGACT TGCCGAGCTCTCGCCGGCCCTGGCGGGGCCCCATCTCTCGCAAGGCCAGCCAGACCAGCGTGTACCTGCA GGAGTGGGACATCCCCTTCGAGCAGGTAGAGCTGGGCGAGCCCATCGGGCAGGGCCGCTGGGGCCGGGTG CACCGCGGCCGCTGGCATGGCGAGGTGGCCATTCGCCTGCTGGAGATGGACGGCCACAACCAGGACCACC TGAAGCTCTTCAAGAAAGAGGTGATGAACTACCGGCAGACGCGGCATGAGAACGTGGTGCTCTTCATGGG GGCCTGCATGAACCCGCCCCACCTGGCCATTATCACCAGCTTCTGCAAGGGGCGGACGTTGCACTCGTTT GTGAGGGACCCCAAGACGTCTCTGGACATCAACAAGACGAGGCAAATCGCTCAGGAGATCATCAAGGGCA TGGGATATCTTCATGCCAAGGGCATCGTACACAAAGATCTCAAATCTAAGAACGTCTTCTATGACAACGG CAAGGTGGTCATCACAGACTTCGGGCTGTTTGGGATCTCAGGCGTGGTCCGAGAGGGACGGCGTGAGAAC CAGCTAAAGCTGTCCCACGACTGGCTGTGCTATCTGGCCCCTGAGATTGTACGCGAGATGACCCCCGGGA AGGACGAGGATCAGCTGCCATTCTCCAAAGCTGCTGATGTCTATGCATTTGGGACTGTTTGGTATGAGCT GCAAGCAAGAGACTGGCCCTTGAAGAACCAGGCTGCAGAGGCATCCATCTGGCAGATTGGAAGCGGGGAA GGAATGAAGCGTGTCCTGACTTCTGTCAGCTTGGGGAAGGAAGTCAGTGAGATCCTGTCGGCCTGCTGGG CTTTCGACCTGCAGGAGAGACCCAGCTTCAGCCTGCTGATGGACATGCTGGAGAAACTTCCCAAGCTGAA CCGGCGGCTCTCCCACCCTGGACACTTCTGGAAGTCAGCTGAGTTGTAG Clone variation with respect to NM_014238.1 288:t=>g |
| Restriction Sites | Please inquire |
| ACCN | NM_014238 |
| Insert Size | 2300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found the protein assciated with this clone is identical to NM_014238.1. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014238.1, NP_055053.1 |
| RefSeq Size | 4552 bp |
| RefSeq ORF | 2289 bp |
| Locus ID | 8844 |
| UniProt ID | Q8IVT5 |
| Protein Families | Druggable Genome, Protein Kinase |
| Gene Summary | Scaffolding protein that is part of a multiprotein signaling complex. Promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Does not have kinase activity by itself.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
SILAC-based phosphoproteomics reveals an inhibitory role of KSR1 in p53 transcriptional activity via modulation of DBC1
,Zhang, H;Xu, Y;Filipovic, A;Lit, LC;Koo, CY;Stebbing, J;Giamas, G;,
Br J Cancer. 2013 Nov 12;109(10):2675-84
,PubMed ID 24129246
[KSR1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211770 | KSR1 (Myc-DDK-tagged)-Human kinase suppressor of ras 1 (KSR1) |
CNY 5,584.00 |
|
| RC211770L1 | Lenti-ORF clone of KSR1 (Myc-DDK-tagged)-Human kinase suppressor of ras 1 (KSR1) |
CNY 7,984.00 |
|
| RC211770L2 | Lenti-ORF clone of KSR1 (mGFP-tagged)-Human kinase suppressor of ras 1 (KSR1) |
CNY 7,700.00 |
|
| RC211770L3 | Lenti-ORF clone of KSR1 (Myc-DDK-tagged)-Human kinase suppressor of ras 1 (KSR1) |
CNY 7,700.00 |
|
| RC211770L4 | Lenti-ORF clone of KSR1 (mGFP-tagged)-Human kinase suppressor of ras 1 (KSR1) |
CNY 7,700.00 |
|
| RG211770 | KSR1 (tGFP-tagged) - Human kinase suppressor of ras 1 (KSR1) |
CNY 6,370.00 |
