FAM195B (MCRIP1) (NM_001093767) Human Untagged Clone
CAT#: SC316100
FAM195B (untagged)-Human family with sequence similarity 195, member B (FAM195B), transcript variant 2
CNY 3,990.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | FAM195B; GRAN2; MCRIP |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_001093767, the custom clone sequence may differ by one or more nucleotides
ATGACCAGCTCCCCCGTCTCCAGAGTCGTGTACAACGGCAAGAGGACCAGCAGCCCCCGC TCCCCACCCAGCAGCAGCGAGATCTTCACCCCAGCCCACGAGGAGAACGTCCGCTTCATT TACGAAGCCTGGCAGGGTGTGGAGCGAGACCTGCGAGGCCAGGTGCCGGGTGGCGAGCGG GGCCTGGTGGAGGAGTATGTGGAGAAGGTCCCTAACCCCAGCCTGAAGACCTTCAAGCCC ATCGACCTGAGTGACCTGAAGCGCCGGAGCACGCAGGATGCCAAGAAGTCC |
Restriction Sites | Please inquire |
ACCN | NM_001093767 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001093767.1, NP_001087236.1 |
RefSeq Size | 951 bp |
RefSeq ORF | 294 bp |
Locus ID | 348262 |
UniProt ID | C9JLW8 |
Gene Summary | The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition (PubMed:25728771).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 3. Variants 1 and 2 encode the same isoform (2), which is shorter at the N-terminus, compared to isoform 1. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC213120 | FAM195B (Myc-DDK-tagged)-Human family with sequence similarity 195, member B (FAM195B), transcript variant 2 |
CNY 3,990.00 |
|
RC213120L3 | Lenti-ORF clone of FAM195B (Myc-DDK-tagged)-Human family with sequence similarity 195, member B (FAM195B), transcript variant 2 |
CNY 5,890.00 |
|
RC213120L4 | Lenti-ORF clone of FAM195B (mGFP-tagged)-Human family with sequence similarity 195, member B (FAM195B), transcript variant 2 |
CNY 5,890.00 |
|
RG213120 | FAM195B (tGFP-tagged) - Human family with sequence similarity 195, member B (FAM195B), transcript variant 2 |
CNY 4,370.00 |
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