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Munc 13 4 (UNC13D) (NM_199242) Human Untagged Clone
CAT＃: SC316030
UNC13D (untagged)-Human unc-13 homolog D (C. elegans) (UNC13D)
CNY 11,392.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FHL3; HLH3; HPLH3; Munc13-4 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>NCBI ORF sequence for NM_199242, the custom clone sequence may differ by one or more nucleotides
ATGGCGACACTCCTCTCCCATCCGCAGCAGCGCCCTCCCTTCTTGCGCCAGGCCATCAAG ATAAGGCGCCGCAGAGTCAGAGATCTACAGGATCCCCCGCCCCAAATGGCCCCGGAGATC CAGCCTCCATCCCACCACTTCTCCCCCGAGCAGCGGGCCCTGCTCTACGAGGACGCACTC TACACTGTCTTGCACCGCCTGGGTCATCCTGAGCCCAACCATGTGACGGAGGCCTCTGAG CTGCTGCGATACCTGCAGGAGGCCTTCCACGTGGAGCCCGAGGAGCACCAGCAGACACTG CAGCGGGTCAGGGAGCTTGAGAAGCCAATATTTTGTCTGAAGGCAACAGTGAAACAGGCC AAGGGCATTCTGGGCAAAGATGTCAGTGGGTTCAGCGACCCCTACTGCCTGCTGGGCATT GAGCAGGGGGTAGGTGTGCCAGGGGGCAGCCCCGGGTCCCGGCATCGGCAGAAGGCTGTG GTGAGGCACACCATCCCCGAGGAGGAGACCCACCGCACGCAGGTCATCACCCAGACACTC AACCCCGTCTGGGACGAGACCTTCATCCTGGAGTTTGAGGACATCACCAATGCGAGCTTT CATCTGGACATGTGGGACCTGGACACTGTGGAGTCTGTCCGACAGAAGCTTGGGGAGCTC ACGGATCTGCATGGGCTTCGCAGGATCTTTAAAGAGGCCCGGAAGGACAAAGGCCAGGAC GACTTTCTGGGGAACGTGGTTCTGAGGCTGCAGGACCTGCGCTGCCGAGAGGACCAGTGG TACCCCCTGGAACCCCGCACTGAGACCTACCCAGACCGAGGCCAGTGCCACCTCCAGTTC CAACTCATCCATAAGCGGAGAGCCACTTCGGCCAGCCGCTCGCAGCCGAGCTACACCGTG CACCTCCACCTCCTGCAGCAGCTTGTGTCCCACGAGGTCACCCAGCACGAGGCGGGAAGC ACCTCCTGGGACGGGTCGCTGAGTCCCCAGGCTGCCACCGTCCTCTTTCTGCACGCCACA CAGAAGGACCTATCCGACTTCCACCAGTCCATGGCGCAGTGGCTGGCCTACAGCCGCCTC TACCAGAGCCTGGAGTTCCCCAGCAGCTGCCTCCTGCACCCCATCACCAGCATCGAGTAC CAGTGGATCCAGGGTCGGCTCAAGGCAGAACAGCAGGAGGAGCTGGCCGCCTCATTCAGC TCCCTGCTGACCTACGGCCTCTCCCTCATCCGGAGGTTCCGCTCTGTCTTCCCCCTCTCT GTCTCGGACTCCCCAGCCCGGCTGCAGTCTCTTCTCAGGGTCCTGGTACAGATGTGCAAG ATGAAGGCCTTTGGAGAACTGTGCCCCAACACCGCCCCATTGCCCCAGCTGGTGACTGAG GCCCTGCAGACTGGCACCACTGAATGGTTCCACCTGAAGCAGCAGCACCATCAACCCATG GTGCAGGGCATCCCGGAGGCAGGCAAGGCCTTGCTGGGCCTGGTACAGGATGTCATTGGC GACCTGCACCAGTGCCAGCGCACATGGGACAAGATCTTCCACAATACCCTCAAGATCCAC CTCTTCTCCATGGCTTTCCGGGAGCTGCAGTGGCTGGTGGCCAAGCGGGTGCAGGACCAC ACGACGGTTGTGGGTGATGTAGTGTCCCCAGAGATGGGCGAGAGTCTGTTCCAGCTCTAC ATCAGCCTCAAGGAGCTCTGCCAGCTGCGCATGAGCTCCTCAGAGAGGGATGGAGTCCTG GCCCTGGATAATTTCCACCGCTGGTTCCAGCCGGCCATCCCCTCCTGGCTGCAGAAGACG TACAACGAGGCCCTGGCGCGGGTGCAGCGCGCTGTGCAGATGGATGAGCTGGTGCCCCTG GGTGAACTGACCAAGCACAGCACATCAGCGGTGGATCTATCCACCTGCTTTGCCCAGATC AGCCACACTGCCCGGCAGCTGGACTGGCCAGACCCAGAGGAGGCCTTCATGATTACCGTC AAGTTTGTGGAGGACACCTGTCGCCTGGCCCTGGTGTACTGCAGCCTTATAAAGGCCCGG GCCCGCGAGCTCTCTTCAGGCCAGAAGGACCAAGGCCAGGCAGCCAACATGCTGTGTGTG GTGGTGAATGACATGGAGCAGCTGCGGCTGGTGATCGGCAAGTTGCCCGCCCAGCTGGCA TGGGAGGCCCTGGAGCAGCGGGTAGGGGCCGTGCTGGAGCAGGGGCAGCTGCAGAACACG CTGCATGCCCAGCTGCAGAGCGCGCTGGCCGGGCTGGGCCATGAGATCCGCACTGGCGTC CGCACCCTGGCCGAGCAGTTGGAGGTGGGCATCGCCAAGCACATCCAGAAACTGGTGGGC GTCAGGGAGTCTGTCCTGCCTGAGGATGCCATTCTGCCCCTGATGAAGTTCCTGGAGGTG GAGCTTTGCTACATGAACACCAACTTGGTGCAGGAGAACTTCAGCAGCCTCCTGACCCTG CTCTGGACCCACACACTCACAGTGCTGGTGGAGGCGGCCGCCTCCCAGCGCAGCTCATCC CTGGCTTCCAACAGGCTGAAGATTGCCCTGCAGAACCTGGAGATCTGCTTCCACGCTGAG GGCTGTGGCCTGCCACCCAAGGCCCTGCACACTGCCACCTTCCAGGCTCTGCAGAGGGAC CTGGAGCTGCAGGCGGCCTCCAGCCGGGAACTCATCCGGAAGTACTTCTGCAGCCGAATC CAGCAGCAGGCAGAAACCACCTCTGAGGAGCTGGGGGCTGTGACAGTCAAGGCCTCCTAC CGCGCCTCTGAGCAGAAGCTGCGTGTGGAGCTGCTCAGCGCCTCCAGCCTGCTGCCCCTG GACTCCAATGGCTCCAGCGACCCCTTTGTCCAGCTGACCTTGGAGCCCAGGCATGAGTTC CCTGAGCTGGCCGCCCGGGAGACCCAGAAGCACAAGAAGGACCTTCACCCATTGTTTGAT GAGACCTTTGAATTCCTGGTGCCTGCTGAGCCGTGCCGCAAGGCTGGGGCATGCCTCCTG CTCACCGTGCTGGACTACGACACGCTGGGGGCCGACGACCTGGAAGGCGAGGCCTTCCTG CCGCTGCGTGAGGTGCCCGGGCTGAGTGGCTCTGAGGAGCCTGGTGAGGTGCCTCAGACC CGCCTGCCCCTCACGTACCCCGCACCCAACGGGGACCCAATCCTGCAGCTGCTGGAGGGC CGGAAGGGTGACCGAGAAGCCCAGGTCTTTGTGAGGCTGCGGCGGCACCGGGCCAAGCAG GCCTCCCAGCATGCCTTGCGGCCGGCACCG |
| Restriction Sites | Please inquire |
| ACCN | NM_199242 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_199242.2, NP_954712.1 |
| RefSeq Size | 4406 bp |
| RefSeq ORF | 3273 bp |
| Locus ID | 201294 |
| UniProt ID | Q70J99 |
| Gene Summary | This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209141 | UNC13D (Myc-DDK-tagged)-Human unc-13 homolog D (C. elegans) (UNC13D) |
CNY 11,384.00 |
|
| RC209141L1 | Lenti ORF clone of Human unc-13 homolog D (C. elegans) (UNC13D), Myc-DDK-tagged |
CNY 13,784.00 |
|
| RC209141L2 | Lenti ORF clone of Human unc-13 homolog D (C. elegans) (UNC13D), mGFP tagged |
CNY 7,600.00 |
|
| RC209141L3 | Lenti ORF clone of Human unc-13 homolog D (C. elegans) (UNC13D), Myc-DDK-tagged |
CNY 7,600.00 |
|
| RC209141L4 | Lenti ORF clone of Human unc-13 homolog D (C. elegans) (UNC13D), mGFP tagged |
CNY 7,600.00 |
|
| RG209141 | UNC13D (tGFP-tagged) - Human unc-13 homolog D (C. elegans) (UNC13D) |
CNY 12,984.00 |
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