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DOPA Decarboxylase (DDC) (NM_001082971) Human Untagged Clone
CAT＃: SC316001
DDC (untagged)-Human dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), transcript variant 1
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AADC |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001082971 edited
GAGGACAGAGAGCAAGTCACTCCCGGCTGCCTTTTTCACCTCTGACAGAGCCCAGACACC ATGAACGCAAGTGAATTCCGAAGGAGAGGGAAGGAGATGGTGGATTACGTGGCCAACTAC ATGGAAGGCATTGAGGGACGCCAGGTCTACCCTGACGTGGAGCCCGGGTACCTGCGGCCG CTGATCCCTGCCGCTGCCCCTCAGGAGCCAGACACGTTTGAGGACATCATCAACGACGTT GAGAAGATAATCATGCCTGGGGTGACGCACTGGCACAGCCCCTACTTCTTCGCCTACTTC CCCACTGCCAGCTCGTACCCGGCCATGCTTGCGGACATGCTGTGCGGGGCCATTGGCTGC ATCGGCTTCTCCTGGGCGGCAAGCCCAGCATGCACAGAGCTGGAGACTGTGATGATGGAC TGGCTCGGGAAGATGCTGGAACTACCAAAGGCATTTTTGAATGAGAAAGCTGGAGAAGGG GGAGGAGTGATCCAGGGAAGTGCCAGTGAAGCCACCCTGGTGGCCCTGCTGGCCGCTCGG ACCAAAGTGATCCATCGGCTGCAGGCAGCGTCCCCAGAGCTCACACAGGCCGCTATCATG GAGAAGCTGGTGGCTTACTCATCCGATCAGGCACACTCCTCAGTGGAAAGAGCTGGGTTA ATTGGTGGAGTGAAATTAAAAGCCATCCCCTCAGATGGCAACTTCGCCATGCGTGCGTCT GCCCTGCAGGAAGCCCTGGAGAGAGACAAAGCGGCTGGCCTGATTCCTTTCTTTATGGTT GCCACCCTGGGGACCACAACATGCTGCTCCTTTGACAATCTCTTAGAAGTCGGTCCTATC TGCAACAAGGAAGACATATGGCTGCACGTTGATGCAGCCTACGCAGGCAGTGCATTCATC TGCCCTGAGTTCCGGCACCTTCTGAATGGAGTGGAGTTTGCAGATTCATTCAACTTTAAT CCCCACAAATGGCTATTGGTGAATTTTGACTGTTCTGCCATGTGGGTGAAAAAGAGAACA GACTTAACGGGAGCCTTTAGACTGGACCCCACTTACCTGAAGCACAGCCATCAGGATTCA GGGCTTATCACTGACTACCGGCATTGGCAGATACCACTGGGCAGAAGATTTCGCTCTTTG AAAATGTGGTTTGTATTTAGGATGTATGGAGTCAAAGGACTGCAGGCTTATATCCGCAAG CATGTCCAGCTGTCCCATGAGTTTGAGTCACTGGTGCGCCAGGATCCCCGCTTTGAAATC TGTGTGGAAGTCATTCTGGGGCTTGTCTGCTTTCGGCTAAAGGGTTCCAACAAAGTGAAT GAAGCTCTTCTGCAAAGAATAAACAGTGCCAAAAAAATCCACTTGGTTCCATGTCACCTC AGGGACAAGTTTGTCCTGCGCTTTGCCATCTGTTCTCGCACGGTGGAATCTGCCCATGTG CAGCGGGCCTGGGAACACATCAAAGAGCTGGCGGCCGACGTGCTGCGAGCAGAGAGGGAG TAGGAGTGAAGCCAGCTGCAGGAATCAAAAATTGAAGAGAGATATATCTGAAAACTGGAA TAAGAAGCAAATAAATATCATCCTGCCTTCATGGAACTCAGCTGTCTGTGGCTTCCCATG TCTTTCTCCAAAGTTATCCAGAGGGTTGTGATTTTGTCTGCTTAGTATCTCATCAACAAA GAAATATTATTTGCTAATTAAAAAGTTAATCTTCATGGCCATAGCTTTTATTCATTAGCT GTGATTTTTGTTGATTAAAACATTATAGATTTTCATGTTCTTGCAGTCATCAGAAGTGGT AGGAAAGCCTCACTGATATATTTTCCAGGGCAATCAATGTTCACGCAACTTGAAATTATA TCTGTGGTCTTCAAATTGTCTTTTGTCATGTGGCTAAATGCCTAATAAACAATTCAAGTG AAATACTAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001082971 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001082971.1, NP_001076440.1 |
| RefSeq Size | 2090 bp |
| RefSeq ORF | 1443 bp |
| Locus ID | 1644 |
| UniProt ID | P20711 |
| Protein Families | Druggable Genome |
| Protein Pathways | Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Tryptophan metabolism, Tyrosine metabolism |
| Gene Summary | The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011] Transcript Variant: This variant (1) has an alternate 5' UTR exon and encodes the same isoform (1), compared to variant 2. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219037 | DDC (Myc-DDK-tagged)-Human dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), transcript variant 1 |
CNY 3,656.00 |
|
| RC219037L1 | Lenti ORF clone of Human dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC219037L2 | Lenti ORF clone of Human dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC219037L3 | Lenti ORF clone of Human dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC219037L4 | Lenti ORF clone of Human dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG219037 | DDC (tGFP-tagged) - Human dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), transcript variant 1 |
CNY 5,256.00 |
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