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Cullin 4B (CUL4B) (NM_001079872) Human Untagged Clone
CAT＃: SC315848
CUL4B (untagged)-Human cullin 4B (CUL4B), transcript variant 2
CNY 17,200.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001079872, the custom clone sequence may differ by one or more nucleotides
ATGTTTCCAACAGGTTTTTCTTCCCCCAGTCCCTCAGCTGCTGCTGCTGCTCAGGAGGTC AGATCTGCCACTGATGGTAATACCAGCACCACTCCGCCCACCTCTGCCAAGAAGAGAAAG TTAAACAGCAGCAGCAGTAGCAGCAGTAACAGTAGTAACGAGAGAGAAGACTTTGATTCC ACCTCTTCCTCCTCTTCCACTCCTCCTTTACAACCCAGGGATTCGGCATCCCCTTCAACC TCGTCCTTCTGCCTGGGGGTTTCAGTGGCTGCTTCCAGCCACGTACCGATACAGAAGAAG CTGCGTTTTGAAGACACCCTGGAGTTTGTAGGGTTTGATGCGAAGATGGCTGAGGAATCC TCCTCCTCCTCCTCCTCATCTTCACCAACTGCTGCAACATCTCAGCAGCAGCAACTTAAA AATAAGAGTATATTAATCTCTTCTGTGGCTTCGGTGCATCATGCAAACGGCCTAGCCAAA TCTTCTACCACCGTCTCTAGCTTTGCTAACAGCAAACCTGGCTCTGCTAAGAAGTTAGTG ATCAAGAACTTTAAAGATAAGCCTAAATTACCAGAAAACTACACAGATGAAACCTGGCAA AAACTGAAAGAAGCAGTGGAAGCTATTCAGAATAGTACTTCAATTAAGTACAATTTAGAA GAACTCTACCAGGCTGTAGAAAATCTCTGTTCTTACAAGATTTCTGCAAACTTGTACAAA CAGCTGAGACAGATCTGCGAAGATCACATCAAAGCACAGATTCATCAATTCAGAGAGGAT TCATTGGATAGCGTTCTTTTTTTAAAGAAGATTGATAGATGCTGGCAAAACCATTGCAGA CAAATGATCATGATCAGGAGCATTTTTTTGTTTCTGGATAGAACTTACGTTCTTCAGAAT TCAATGCTACCCTCCATTTGGGACATGGGACTGGAGTTATTTAGGGCTCATATTATAAGT GATCAGAAAGTGCAGAATAAGACAATTGATGGCATTCTTCTCTTGATTGAGAGGGAAAGG AATGGTGAAGCAATTGATAGAAGTTTACTTCGAAGCCTTTTAAGCATGCTGTCTGATTTG CAAATTTATCAAGATTCTTTTGAACAACGATTTTTGGAAGAAACTAACCGGCTCTATGCA GCTGAAGGCCAAAAATTAATGCAAGAAAGAGAGGTTCCTGAATATCTACATCATGTTAAC AAACGTCTAGAAGAAGAAGCAGACAGACTTATTACTTACTTAGATCAGACCACCCAGAAG TCATTAATTGCTACTGTAGAAAAACAACTTCTAGGTGAACACTTAACAGCAATTCTTCAG AAAGGTTTAAATAACCTCCTTGATGAAAACCGAATTCAAGATTTGTCTCTTCTGTATCAG CTCTTCAGTAGAGTTCGAGGTGGAGTTCAGGTTCTTTTGCAGCAGTGGATCGAATATATC AAGGCATTTGGCAGCACTATTGTAATTAATCCTGAAAAAGATAAAACCATGGTTCAAGAA TTGCTGGATTTTAAAGATAAGGTTGACCATATAATTGATATCTGCTTTCTGAAGAATGAG AAATTTATCAATGCCATGAAAGAAGCATTTGAAACGTTCATTAACAAAAGACCAAATAAA CCAGCTGAACTTATAGCTAAGTATGTAGATTCAAAACTTCGTGCAGGCAACAAAGAAGCT ACAGATGAAGAACTTGAGAAAATGTTGGATAAAATTATGATCATATTTAGATTTATCTAT GGCAAGGATGTTTTTGAGGCCTTCTATAAGAAAGATTTAGCCAAGCGCCTGTTAGTCGGA AAGAGTGCATCTGTAGATGCTGAAAAATCAATGCTGTCCAAACTTAAACATGAATGCGGA GCTGCTTTCACCAGCAAACTTGAAGGAATGTTTAAAGACATGGAACTTTCTAAAGACATC ATGATTCAGTTCAAACAGTATATGCAGAATCAGAATGTTCCGGGAAATATTGAGTTAACT GTGAATATCCTGACAATGGGCTATTGGCCGACATATGTGCCTATGGAAGTTCATTTACCA CCAGAGATGGTAAAACTTCAGGAGATTTTCAAGACATTTTACCTAGGCAAACATAGTGGC AGGAAACTTCAGTGGCAGTCAACCCTAGGACACTGTGTGTTAAAAGCAGAATTTAAAGAG GGTAAAAAGGAACTCCAGGTCTCTCTTTTTCAAACACTGGTGCTGCTAATGTTTAATGAG GGAGAGGAGTTCAGTTTAGAAGAGATCAAGCAGGCAACTGGAATAGAGGATGGAGAGTTA AGGAGAACACTGCAGTCATTAGCCTGTGGCAAAGCTAGAGTTCTGGCGAAAAATCCAAAG GGCAAAGACATTGAAGATGGTGACAAGTTCATTTGTAATGATGATTTCAAACATAAACTT TTCAGGATAAAGATCAATCAAATCCAGATGAAAGAAACGGTTGAAGAACAAGCAAGCACT ACAGAAAGAGTATTTCAAGACAGACAGTATCAAATTGATGCTGCAATTGTTCGAATTATG AAGATGAGAAAGACACTTAGCCACAATCTCCTTGTTTCAGAAGTGTACAACCAGTTGAAA TTTCCAGTAAAGCCTGCTGATCTTAAGAAGAGAATAGAATCTTTAATTGACCGGGACTAC ATGGAAAGAGATAAAGAAAATCCAAACCAGTACAACTATATTGCA |
| Restriction Sites | Please inquire |
| ACCN | NM_001079872 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001079872.1, NP_001073341.1 |
| RefSeq Size | 5198 bp |
| RefSeq ORF | 2688 bp |
| Locus ID | 8450 |
| UniProt ID | Q13620 |
| Protein Pathways | Nucleotide excision repair, Ubiquitin mediated proteolysis |
| Gene Summary | This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (2) has a shorter and unique N-terminus, compared to isoform 1. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220405 | CUL4B (Myc-DDK-tagged)-Human cullin 4B (CUL4B), transcript variant 2 |
CNY 9,410.00 |
|
| RC220405L3 | Lenti-ORF clone of CUL4B (Myc-DDK-tagged)-Human cullin 4B (CUL4B), transcript variant 2 |
CNY 11,310.00 |
|
| RC220405L4 | Lenti-ORF clone of CUL4B (mGFP-tagged)-Human cullin 4B (CUL4B), transcript variant 2 |
CNY 11,310.00 |
|
| RG220405 | CUL4B (tGFP-tagged) - Human cullin 4B (CUL4B), transcript variant 2 |
CNY 10,360.00 |
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