United States
Germany
Japan
United Kingdom
China
PDE11A (NM_001077358) Human Untagged Clone
CAT＃: SC315594
PDE11A (untagged)-Human phosphodiesterase 11A (PDE11A), transcript variant 2
CN¥ 9,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PPNAD2 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001077358, the custom clone sequence may differ by one or more nucleotides
ATGCAGATGTATCTTCCATTTTGTGGAATCGCCATATCTAACGCTCAGCTCTTTGCTGCC TCAAGGAAAGAATATGAAAGAAGCAGAGCTTTGCTAGAGGTGGTTAATGACCTCTTTGAA GAACAGACTGACCTGGAGAAAATTGTCAAGAAAATAATGCATCGGGCCCAAACTCTGCTG AAATGTGAACGCTGTTCTGTTTTACTCCTAGAGGACATCGAATCACCAGTGGTGAAATTT ACCAAATCCTTTGAATTGATGTCCCCAAAGTGCAGTGCTGATGCTGAGAACAGTTTCAAA GAAAGCATGGAGAAATCATCATACTCCGACTGGCTAATAAATAACAGCATTGCTGAGCTG GTTGCTTCAACAGGCCTTCCAGTGAACATCAGTGATGCCTACCAGGATCCGCGCTTTGAT GCAGAGGCAGACCAGATATCTGGTTTTCACATAAGATCTGTTCTTTGTGTCCCTATTTGG AATAGCAACCACCAAATAATTGGAGTGGCTCAAGTGTTAAACAGACTTGATGGGAAACCT TTTGATGATGCAGATCAACGACTTTTTGAGGCTTTTGTCATCTTTTGTGGACTTGGCATC AACAACACAATTATGTATGATCAAGTGAAGAAGTCCTGGGCCAAGCAGTCTGTGGCTCTT GATGTGCTATCATACCATGCAACATGTTCAAAAGCTGAAGTTGACAAGTTTAAGGCAGCC AACATCCCTCTGGTGTCAGAACTTGCCATCGATGACATTCATTTTGATGACTTTTCTCTC GACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGATGGTACAG AAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTAT CGGATGGTTCTATACCACAACTGGAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCG ATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGCGGTGATT GTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAG AGTGGCTCTGCCCTGGCCCAACTCTATGGAACCTCTGCTACCTTGGAGCATCACCATTTC AACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCTGTCCTCC AAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACG CTGTACTTTGAGAGGAGAACTGAATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGG AACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGACCTTGGA GCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTC TTCGAACAAGGAGATCGGGAGAGATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGAT CGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCATCTGCATG CCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTA GCTACAAACAGAAGTAAGTGGGAAGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCC TCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAAC |
| Restriction Sites | Please inquire |
| ACCN | NM_001077358 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001077358.1, NP_001070826.1 |
| RefSeq Size | 1869 bp |
| RefSeq ORF | 1728 bp |
| Locus ID | 50940 |
| UniProt ID | Q9HCR9 |
| Protein Families | Druggable Genome |
| Protein Pathways | Progesterone-mediated oocyte maturation, Purine metabolism |
| Gene Summary | The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 4. The resulting isoform (2) has a shorter N-terminus, compared to isoform 4. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211991 | PDE11A (Myc-DDK-tagged)-Human phosphodiesterase 11A (PDE11A), transcript variant 2 |
CN¥ 4,280.00 |
|
| RC211991L3 | Lenti-ORF clone of PDE11A (Myc-DDK-tagged)-Human phosphodiesterase 11A (PDE11A), transcript variant 2 |
CN¥ 6,460.00 |
|
| RC211991L4 | Lenti-ORF clone of PDE11A (mGFP-tagged)-Human phosphodiesterase 11A (PDE11A), transcript variant 2 |
CN¥ 6,460.00 |
|
| RG211991 | PDE11A (tGFP-tagged) - Human phosphodiesterase 11A (PDE11A), transcript variant 2 |
CN¥ 5,040.00 |
