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IL18 (NM_001562) Human Untagged Clone
CAT＃: SC315485
IL18 (untagged)-Human interleukin 18 (interferon-gamma-inducing factor) (IL18)
CNY 2,400.00
CNY 3,990.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IGIF; IL-1g; IL-18; IL1F4 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001562 edited
CTGGACAGTCAGCAAGGAATTGTCTCCCAGTGCATTTTGCCCTCCTGGCTGCCAACTCTG GCTGCTAAAGCGGCTGCCACCTGCTGCAGTCTACACAGCTTCGGGAAGAGGAAAGGAACC TCAGACCTTCCAGATCGCTTCCTCTCGCAACAAACTATTTGTCGCAGGAATAAAGATGGC TGCTGAACCAGTAGAAGACAATTGCATCAACTTTGTGGCAATGAAATTTATTGACAATAC GCTTTACTTTATAGCTGAAGATGATGAAAACCTGGAATCAGATTACTTTGGCAAGCTTGA ATCTAAATTATCAGTCATAAGAAATTTGAATGACCAAGTTCTCTTCATTGACCAAGGAAA TCGGCCTCTATTTGAAGATATGACTGATTCTGACTGTAGAGATAATGCACCCCGGACCAT ATTTATTATAAGTATGTATAAAGATAGCCAGCCTAGAGGTATGGCTGTAACTATCTCTGT GAAGTGTGAGAAAATTTCAACTCTCTCCTGTGAGAACAAAATTATTTCCTTTAAGGAAAT GAATCCTCCTGATAACATCAAGGATACAAAAAGTGACATCATATTCTTTCAGAGAAGTGT CCCAGGACATGATAATAAGATGCAATTTGAATCTTCATCATACGAAGGATACTTTCTAGC TTGTGAAAAAGAGAGAGACCTTTTTAAACTCATTTTGAAAAAAGAGGATGAATTGGGGGA TAGATCTATAATGTTCACTGTTCAAAACGAAGACTAGCTATTAAAATTTCATGCCGGGCG CAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCTGAGGCGGGCAGATCACCAGAG GTCAGGTGTTCAAGACCAGCCTGACCAACATGGTGAAACCTTCATCTCTACTAAAAATAC AAAAAATTAGCTGAGTGTAGTGACCCATGCCCTCAATCCCGGCTACTCAAGAGGCTGAGG CAGGAGAATCACTTGCACTCCGGAGGTGGAGGTTGTGGTGAGCCGAGATTGCACCATTGC GCTCTAGCCTGGGCAACAACAGCAAAACTCCATCTCAAAAAATAAAATAAATAAATAAAC AAATAAAAAATTCAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_001562 unedited
CAACACANTTCGCACGAGGCTGGACAGTTTTCAAGGAATTGTCTCCCAGTGCATTTTGCC CTCCTGGCTGCCAACTCTGGCTGCTAAAGCGGCTGCCACCTGCTGCAGTCTACACAGCTT CGGGAAGAGGAAAGGAACCTCAGACCTTCCAGATCGCTTCCTCTCGCAACAAACTATTTG NCTCAGTGATAAAGATGGCTGCTGAACCAGTAGAAGACAATTGCATCAACTTTGTGGCAA TGAAATTTATTGACAATACGCTTTACTTTATAGCTGAAGATGATGAAAACCTGGAATCAG ATTACTTTGGCAAGCTTGAATCTAAATTATCAGTCATAAGAAATTTGAATGACCAAGTTC TCTTCATTGACCAAGGAAATCGGCCTCTATTTGAAGATATGACTGATTCTGACTGTAGAG ATAATGCACCCCGGACCATATTTATTATAAGTATGTATAAAGATAGCCAGCCTAGAGGTA TGGCTGTAACTATCTCTGTGAAGTGTGAGAAAATTTCAACTCTCTCCTGTGAGAACAAAA TTATTTCCTTTAAGGAAATGAATCCTCCTGATAACATCAAGGATACAAAAAGTGACATCA TATTCTTTCAGAGGAGTGTCCCANGACATGATAATAAGATGCAATTTGAATCTTTCTCAT ACGAAAGATACTTTCTAGCTTGTGAAAAGAGAGAGACCTTTTAAACTCATTTTGAAAAAA GAGAAGAAATGGGGGATAGATCTATAATGTTCACTGGTCAAACGAAGACTAACTTTAAAA TTTCTGCCCGGCGCAGGGCGTTACCCCCGCAACCCCGGCCCGTTGCGGTAGCTCAGCGGG GGACCACTACTTATTCATGGTCGCGATGAGCCACCAGCGATCCGTTGATACCAG >OriGene 3' read for NM_001562 unedited
CTATGAACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGAATTTTTTA TTTGTTTATTTATTTATTTTATTTTTTGAGATGGAGTTTTGCTGTTGTTGCCCAGGCTAG AGCGCAATGGTGCAATCTCGGCTCACCACAACCTCCACCTCCGGAGTGCAAGTGATTCTC CTGCCTCAGCCTCTTGAGTAGCCGGGATTGAGGGCATGGGTCACTACACTCAGCTAATTT TTTGTATTTTTAGTAGAGATGAAGGTTTCACCATGTTGGTCAGGCTGGTCTTGAACACCT GACCTCTGGTGATCTGCCCGCCTCAGCCTCCCAAAGGGCTGGGATTACAGGCGTGAGCCA CTGCGCCCGGCATGAAATTTTAATAGCTAGTCTTCGTTTTGAACAGTGAACATTATAGAT CTATCCCCCAATTCATCCTCTTTTTTCAAAATGAGTTTAAAAAGGTCTCTCTCTTTTTCA CAAGCTAGAAAGTATCCTTCGTATGATGAAGATTCAAATTGCATCTTATTATCATGTCCT GGGACACTTCTCTGAAAGAATATGATGTCACTTTTTGTATCCTTGATGTTATCAGGAGGA TTCATTTCCTTAAAGGAAATAATTTTGTTCTCACAGGAGAGAGTTGAAATTTTCTCACAC TTCACAGAGATAGTTACAGCCATACCTCTAGGCTGGCTATCTTTATACATACTTATAATA AATATGGTCCCGGGTGCATTATCTCTACAGTCAGAATCAATCATATCTTCCAATAGAGGC CGATTTCCTTGGTCAATGAAGAGAACTTGGTCATTCAAATTTCCTATGACTGATAATTTA GATTCAGCTTGCCCAATAATCTGATCCCAGTTTTCATCATCCTCAGCTTTAAGAAAGCGT ATGTCAATAATTTCTTGGCCCAATTTATGCATTGTCTCTACTTGTTCACACCCTCCTTAT CCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001562 |
| Insert Size | 1200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001562.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001562.2, NP_001553.1 |
| RefSeq Size | 1145 bp |
| RefSeq ORF | 582 bp |
| Locus ID | 3606 |
| UniProt ID | Q14116 |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, NOD-like receptor signaling pathway |
| Gene Summary | The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020] Transcript Variant: This variant (1) represents the predominant and longer transcript, and encodes the longer isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Mast cells induce epithelial-to-mesenchymal transition and stem cell features in human thyroid cancer cells through an IL-8-Akt-Slug pathway
,Visciano, C;Liotti, F;Prevete, N;Cali', G;Franco, R;Collina, F;de Paulis, A;Marone, G;Santoro, M;Melillo, RM;,
Oncogene
,PubMed ID 25619830
[IL18]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202716 | IL18 (Myc-DDK-tagged)-Human interleukin 18 (interferon-gamma-inducing factor) (IL18) |
CNY 2,400.00 |
|
| RC202716L1 | Lenti ORF clone of Human interleukin 18 (interferon-gamma-inducing factor) (IL18), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC202716L2 | Lenti ORF clone of Human interleukin 18 (interferon-gamma-inducing factor) (IL18), mGFP tagged |
CNY 5,890.00 |
|
| RC202716L3 | Lenti ORF clone of Human interleukin 18 (interferon-gamma-inducing factor) (IL18), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC202716L4 | Lenti ORF clone of Human interleukin 18 (interferon-gamma-inducing factor) (IL18), mGFP tagged |
CNY 4,800.00 |
|
| RG202716 | IL18 (tGFP-tagged) - Human interleukin 18 (interferon-gamma-inducing factor) (IL18) |
CNY 4,000.00 |
