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SCAP (NM_012235) Human Untagged Clone
CAT＃: SC315330
SCAP (untagged)-Human SREBF chaperone (SCAP)
CNY 8,912.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_012235 edited
AGGGTGATCCATGGTCACTTTCCGGGATGGCAGCAAGGTGACTTCGGCTGAGGATGACCC TGACTGAAAGGCTGCGTGAGAAGATATCTCGGGCCTTCTACAACCATGGGCTCCTCTGTG CATCCTATCCCATCCCCATCATCCTCTTCACAGGGTTCTGCATCTTAGCCTGCTGCTACC CACTGCTGAAACTCCCCTTGCCAGGAACAGGACCTGTGGAATTCACCACCCCTGTGAAGG ATTACTCGCCCCCACCTGTGGACTCTGACCGCAAACAAGGAGAGCCTACTGAGCAGCCTG AGTGGTATGTGGGTGCCCCGGTGGCTTATGTCCAGCAGATATTTGTGAAGTCCTCAGTGT TTCCCTGGCACAAGAACCTCCTGGCAGTAGATGTATTTCGTTCACCTTTGTCCCGGGCAT TCCAACTGGTGGAGGAGATCCGGAACCACGTGCTGAGAGACAGCTCTGGGATCAGGAGCT TGGAGGAGTTGTGTCTGCAAGTGACCGACCTGCTGCCAGGCCTTAGGAAGCTCAGGAACC TACTCCCTGAGCATGGATGCCTGCTGCTGTCCCCTGGGAACTTCTGGCAGAATGACTGGG AACGCTTCCATGCTGATCCTGACATCATTGGGACCATCCACCAGCACGAGCCTAAAACCC TGCAGACTTCAGCCACACTCAAAGACTTGTTATTTGGTGTTCCTGGGAAGTACAGCGGGG TGAGCCTCTACACCAGGAAGAGGATGGTCTCCTACACCATCACCCTGGTCTTCCAGCACT ACCATGCCAAGTTCCTGGGCAGCCTGCGTGCCCGCCTGATGCTTCTGCACCCCAGCCCCA ACTGCAGCCTTCGGGCGGAGAGCCTGGTCCACGTGCACTTCAAGGAGGAGATTGGTGTCG CTGAGCTCATCCCCCTTGTGACCACCTACATCATCTTGTTTGCCTACATCTACTTCTCCA CGCGGAAGATCGACATGGTCAAGTCCAAGTGGGGGCTGGCCCTGGCTGCCGTGGTCACAG TGCTCAGCTCGCTGCTCATGTCTGTGGGACTCTGCACACTCTTCGGCCTGACGCCCACCC TCAATGGCGGCGAGATTTTCCCCTACCTTGTGGTGGTTATTGGGTTAGAGAATGTGTTGG TGCTCACCAAGTCTGTGGTCTCAACCCCGGTAGACCTGGAGGTGAAGCTGCGGATCGCCC AAGGCCTAAGCAGCGAGAGCTGGTCCATCATGAAGAACATGGCCACGGAGCTGGGCATCA TCCTCATCGGCTACTTCACCCTAGTGCCCGCCATCCAGGAGTTCTGTCTCTTTGCTGTCG TGGGGCTGGTGTCTGACTTCTTCCTTCAGATGCTGTTTTTCACCACTGTCCTGTCCATTG ACATTCGCCGGATGGAGCTAGCAGACCTGAACAAGCGACTGCCCCCTGAGGCCTGCCTGC CCTCAGCCAAGCCAGTGGGGCAGCCAACGCGCTACGAGCGGCAGCTGGCTGTGAGGCCGT CCACACCCCACACCATCACGTTGCAGCCGTCTTCCTTCCGAAACCTGCGGCTCCCCAAGA GGCTGCGTGTTGTCTACTTCCTGGCCCGCACCCGCCTGGCACAGCGCCTCATCATGGCTG GCACCGTTGTCTGGATTGGCATCCTGGTATACACAGACCCAGCAGGGCTGCGCAACTACC TCGCTGCCCAGGTGACGGAACAGAGCCCATTGGGTGAGGGAGCCCTGGCTCCCATGCCCG TGCCTAGTGGCATGCTGCCCCCCAGCCACCCGGACCCTGCCTTCTCCATCTTCCCACCTG ATGCCCCTAAGCTACCTGAGAACCAGACGTCGCCAGGCGAGTCACCTGAGCGTGGAGGTC CAGCAGAGGTTGTCCATGACAGCCCAGTCCCAGAGGTAACCTGGGGGCCTGAGGATGAGG AACTTTGGAGGAAATTGTCCTTCCGCCACTGGCCGACGCTCTTCAGCTATTACAACATCA CACTGGCCAAGAGGTACATCAGCCTGCTGCCCGTCATCCCAGTCACGCTCCGCCTGAACC CGAGGGAGGCTCTGGAGGGCCGGCACCCTCAGGACGGCCGCAGTGCCTGGCCCCCACCGG GGCCCATACCTGCTGGGCACTGGGAAGCAGGACCCAAGGGCCCAGGTGGGGTGCAGGCCC ATGGAGACGTCACGCTGTACAAGGTGGCGGCGCTGGGCCTGGCCACCGGCATCGTCTTGG TGCTGCTGCTGCTCTGCCTCTACCGCGTGCTATGCCCGCGCAACTACGGGCAGCTGGGTG GTGGGCCCGGGCGGCGGAGGCGCGGGGAGCTGCCCTGCGACGACTACGGCTATGCGCCAC CCGAGACGGAGATCGTGCCGCTTGTGCTGCGCGGCCACCTCATGGACATCGAGTGCCTGG CCAGCGACGGCATGCTGCTGGTGAGCTGCTGCCTGGCAGGCCACATCTGCGTGTGGGACG CGCAGACCGGGGATTGCCTAACGCGCATTCCGCGCCCAGGCAGGCAGCGCCGGGACAGTG GCGTGGGCAGCGGGCTTGAGGCTCAGGAGAGCTGGGAACGACTTTCAGATGGTGGGAAGG CTGGTCCAGAGGAGCCTGGGGACAGCCCTCCCCTGAGACACCGCCCCCGGGGCCCTCCGC CGCCTTCCCTCTTCGGGGACCAGCCTGACCTCACCTGCTTAATTGACACCAACTTTTCAG CGCAGCCTCGGTCCTCACAGCCCACTCAGCCCGAGCCCCGGCACCGGGCGGTCTGTGGCC GCTCTCGGGACTCCCCAGGCTATGACTTCAGCTGCCTGGTGCAGCGGGTGTACCAGGAGG AGGGGCTGGCGGCCGTCTGCACACCAGCCCTGCGCCCACCCTCGCCTGGGCCGGTGCTGT CCCAGGCCCCTGAGGACGAGGGTGGCTCCCCCGAGAAAGGCTCCCCTTCCCTCGCCTGGG CCCCCAGTGCCGAGGGTTCCATCTGGAGCTTGGAGCTGCAGGGCAACCTCATCGTGGTGG GGCGGAGCAGCGGCCGGCTGGAGGTGTGGGACGCCATTGAAGGGGTGCTGTGCTGCAGCA GCGAGGAGGTCTCCTCAGGCATTACCGCTCTGGTGTTCTTGGACAAAAGGATTGTGGCTG CACGGCTCAACGGTTCCCTTGATTTCTTCTCCTTGGAGACCCACACTGCCCTCAGCCCCC TGCAGTTTAGAGGGACCCCAGGGCGGGGCAGTTCCCCTGCCTCTCCAGTGTACAGCAGCA GCGACACAGTGGCCTGTCACCTGACCCACACAGTGCCCTGTGCACACCAAAAACCCATCA CAGCCCTGAAAGCCGCTGCTGGGCGCTTGGTGACTGGGAGCCAAGACCACACACTGAGAG TGTTCCGTCTGGAGGACTCGTGCTGCCTCTTCACCCTTCAGGGCCACTCAGGGGCCATCA CGACCGTGTACATTGACCAGACCATGGTGCTGGCCAGTGGAGGACAAGATGGGGCCATCT GCCTGTGGGATGTACTGACTGGCAGCCGGGTCAGCCATGTGTTTGCTCACCGTGGGGATG TCACCTCCCTTACCTGTACCACCTCCTGTGTCATCAGCAGTGGCCTGGATGACCTCATCA GCATCTGGGACCGCAGCACAGGCATCAAGTTCTACTCCATTCAGCAGGACCTGGGCTGTG GTGCAAGCTTGGGTGTCATCTCAGACAACCTGCTGGTGACTGGCGGCCAGGGCTGTGTCT CCTTTTGGGACCTAAACTACGGGGACCTGTTACAGACAGTCTACCTGGGGAAGAACAGTG AGGCCCAGCCTGCCCGCCAGATCCTGGTGCTGGACAACGCTGCCATTGTCTGCAACTTTG GCAGTGAGCTCAGCCTGGTGTATGTGCCCTCTGTGCTGGAGAAGCTGGACTGAGCGCAGG GCCTCCTTGCCCAGGCAGGAGGCTGGGGTGCTGTGTGGGGGCCAATGCACTGAACCTGGA CTTGGGGGAAAGAGCCGAGTATCTTCCAGCCGCTGCCTCCTGACTGTAATAATATTAAAC TTTTTTAAAAAACCATAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_012235 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | It is not a varient. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_012235.2, NP_036367.2 |
| RefSeq Size | 4255 bp |
| RefSeq ORF | 3840 bp |
| Locus ID | 22937 |
| UniProt ID | Q12770 |
| Domains | WD40 |
| Protein Families | Druggable Genome, Transcription Factors, Transmembrane |
| Gene Summary | This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223734 | SCAP (Myc-DDK-tagged)-Human SREBF chaperone (SCAP) |
CNY 8,904.00 |
|
| RC223734L1 | Lenti ORF clone of Human SREBF chaperone (SCAP), Myc-DDK-tagged |
CNY 11,304.00 |
|
| RC223734L2 | Lenti ORF clone of Human SREBF chaperone (SCAP), mGFP tagged |
CNY 11,500.00 |
|
| RC223734L3 | Lenti ORF clone of Human SREBF chaperone (SCAP), Myc-DDK-tagged |
CNY 11,304.00 |
|
| RC223734L4 | Lenti ORF clone of Human SREBF chaperone (SCAP), mGFP tagged |
CNY 11,304.00 |
|
| RG223734 | SCAP (tGFP-tagged) - Human SREBF chaperone (SCAP) |
CNY 10,504.00 |
