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HIPK3 (NM_005734) Human Untagged Clone
CAT＃: SC315273
HIPK3 (untagged)-Human homeodomain interacting protein kinase 3 (HIPK3), transcript variant 1
CNY 23,470.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DYRK6; FIST3; PKY; YAK1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC315273 representing NM_005734.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCCTCACAAGTCTTGGTCTACCCACCATATGTTTATCAAACTCAGTCAAGTGCCTTTTGTAGTGTG AAGAAACTCAAAGTAGAGCCAAGCAGTTGTGTATTCCAGGAAAGAAACTATCCACGGACCTATGTGAAT GGTAGAAACTTTGGAAATTCTCATCCTCCCACTAAGGGTAGTGCTTTTCAGACAAAGATACCATTTAAT AGACCTCGAGGACACAACTTTTCATTGCAGACAAGTGCTGTTGTTTTGAAAAACACTGCAGGTGCTACA AAGGTCATAGCAGCTCAGGCACAGCAAGCTCACGTGCAGGCACCTCAGATTGGGGCGTGGCGAAACAGA TTGCATTTCCTAGAAGGCCCCCAGCGATGTGGATTGAAGCGCAAGAGTGAGGAGTTGGATAATCATAGC AGCGCAATGCAGATTGTCGATGAATTGTCCATACTTCCTGCAATGTTGCAAACCAACATGGGAAATCCA GTGACAGTTGTGACAGCTACCACAGGATCAAAACAGAATTGTACCACTGGAGAAGGTGACTATCAGTTA GTACAGCATGAAGTCTTATGCTCCATGAAAAATACTTACGAAGTCCTTGATTTTCTTGGTCGAGGCACG TTTGGCCAGGTAGTTAAATGCTGGAAAAGAGGGACAAATGAAATTGTAGCAATCAAAATTTTGAAGAAT CATCCTTCTTATGCCCGTCAAGGTCAAATAGAAGTGAGCATATTAGCAAGGCTCAGTACTGAAAATGCT GATGAATATAACTTTGTACGAGCTTATGAATGCTTTCAGCACCGTAACCATACTTGTTTAGTCTTTGAG ATGCTGGAACAAAACTTGTATGACTTTCTGAAACAAAATAAATTTAGTCCCCTGCCACTAAAAGTGATT CGGCCCATTCTTCAACAAGTGGCCACTGCACTGAAAAAATTGAAAAGTCTTGGTTTAATTCATGCTGAT CTCAAGCCAGAGAATATTATGTTGGTGGATCCTGTTCGGCAGCCTTACAGGGTTAAAGTAATAGACTTT GGGTCGGCCAGTCATGTATCAAAGACTGTTTGTTCAACATATCTACAATCTCGGTACTACAGAGCTCCA GAGATTATATTGGGGTTGCCATTTTGTGAAGCCATAGACATGTGGTCATTGGGATGTGTGATTGCAGAA TTATTTCTTGGATGGCCGCTCTACCCAGGAGCCTTGGAGTATGATCAGATTCGATACATTTCTCAGACT CAAGGTTTGCCAGGAGAACAGTTGTTAAATGTGGGTACTAAATCCACAAGATTTTTTTGCAAAGAAACA GATATGTCTCATTCTGGTTGGAGATTAAAGACATTGGAAGAGCATGAGGCAGAGACAGGAATGAAGTCT AAAGAAGCCAGAAAATACATTTTCAACAGTCTGGATGATGTAGCGCATGTGAACACAGTGATGGATTTG GAAGGAAGTGATCTTTTGGCTGAGAAAGCTGATAGAAGAGAATTTGTTAGTCTGTTGAAGAAAATGTTG CTGATTGATGCAGATTTAAGAATTACTCCAGCTGAGACCCTGAACCATCCTTTTGTTAATATGAAACAT CTTCTAGATTTCCCTCATAGCAACCATGTAAAGTCCTGTTTTCATATTATGGATATTTGTAAGTCCCAC CTAAATTCATGTGACACAAATAATCACAACAAAACTTCACTTTTAAGACCAGTTGCTTCAAGCAGTACT GCTACACTGACTGCAAATTTTACTAAAATCGGAACATTAAGAAGTCAGGCATTGACCACATCTGCTCAT TCAGTTGTGCACCATGGAATACCTCTGCAGGCAGGAACTGCTCAGTTTGGTTGTGGTGATGCTTTTCAG CAGACATTGATTATCTGTCCCCCAGCTATTCAAGGTATTCCTGCAACACATGGTAAACCCACCAGTTAT TCAATAAGGGTAGATAATACAGTTCCACTTGTAACTCAGGCCCCAGCTGTGCAGCCACTACAGATCCGA CCAGGAGTTCTTTCTCAGACGTGGTCTGGTAGAACACAGCAGATGCTGGTGCCTGCCTGGCAACAGGTG ACACCCCTGGCTCCTGCTACTACTACACTAACTTCTGAGAGTGTGGCTGGTTCACACAGGCTTGGAGAC TGGGGGAAGATGATTTCATGCAGCAATCATTATAACTCAGTGATGCCGCAGCCTCTTCTGACCAATCAG ATAACTTTATCTGCCCCTCAGCCAGTTAGTGTGGGGATTGCACATGTTGTCTGGCCTCAGCCTGCCACT ACCAAGAAAAATAAACAGTGCCAGAACAGAGGTATTTTGGTAAAACTAATGGAATGGGAGCCAGGAAGA GAGGAAATAAATGCTTTCAGTTGGAGTAATTCATTACAGAATACCAATATCCCACATTCAGCATTTATT TCTCCAAAGATAATTAATGGGAAAGATGTCGAGGAAGTAAGTTGTATAGAAACACAGGACAATCAGAAC TCAGAAGGAGAGGCAAGAAATTGCTGTGAAACATCTATCAGACAGGACTCTGATTCATCAGTTTCAGAC AAACAGCGGCAAACCATCATTATTGCCGACTCCCCGAGTCCTGCAGTGAGTGTCATCACTATCAGCAGT GACACTGATGAGGAAGAGACTTCCCAGAGACATTCACTCAGAGAATGTAAAGGTAGTCTAGATTGTGAA GCTTGCCAGAGCACTTTGAATATTGATCGGATGTGTTCATTAAGTAGTCCTGATAGTACTCTGAGTACC AGCTCCTCAGGGCAGTCCAGCCCATCCCCCTGCAAGAGACCGAATAGTATGTCAGATGAAGAGCAAGAA AGTAGTTGTGATACGGTGGATGGCTCTCCGACATCTGACTCTTCCGGGCATGACAGTCCATTTGCAGAG AGCACTTTTGTGGAGGACACTCATGAAAACACAGAATTGGTATCCTCTGCTGACACAGAAACCAAGCCA GCTGTCTGTTCTGTTGTGGTGCCACCAGTGGAACTAGAAAATGGCTTAAATGCCGATGAGCATATGGCA AACACAGATTCTATATGCCAGCCATTAATAAAAGGACGATCTGCCCCTGGAAGATTAAACCAGCCTTCT GCAGTGGGTACTCGTCAGCAAAAATTGACATCAGCATTCCAGCAGCAGCATTTGAACTTCAGTCAGGTT CAGCACTTTGGATCTGGGCATCAAGAGTGGAATGGAAACTTTGGGCACAGAAGACAGCAAGCTTATATT CCTACTAGTGTTACCAGTAATCCATTCACTCTTTCTCATGGAAGTCCCAATCACACAGCAGTGCATGCC CACCTGGCTGGAAATACACACCTCGGAGGACAGCCTACTCTACTTCCATACCCATCATCAGCCACCCTC AGTAGTGCTGCACCAGTGGCCCACCTGTTAGCCTCTCCGTGTACCTCAAGACCTATGTTACAGCATCCA ACTTATAATATCTCCCATCCCAGTGGCATAGTTCACCAAGTCCCAGTGGGCTTAAATCCCCGTCTGTTA CCATCCCCAACCATTCATCAGACTCAGTACAAACCAATCTTCCCACCACATTCTTACATTGCAGCATCA CCTGCATATACTGGATTTCCACTGAGTCCAACAAAACTCAGCCAGTATCCATATATGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_005734 |
| Insert Size | 3648 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005734.4 |
| RefSeq Size | 7684 bp |
| RefSeq ORF | 3648 bp |
| Locus ID | 10114 |
| UniProt ID | Q9H422 |
| Domains | pkinase, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase, Transcription Factors |
| MW | 133.7 kDa |
| Gene Summary | Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214196 | HIPK3 (Myc-DDK-tagged)-Human homeodomain interacting protein kinase 3 (HIPK3), transcript variant 1 |
CNY 8,464.00 |
|
| RC214196L1 | Lenti ORF clone of Human homeodomain interacting protein kinase 3 (HIPK3), transcript variant 1, Myc-DDK-tagged |
CNY 10,864.00 |
|
| RC214196L2 | Lenti ORF clone of Human homeodomain interacting protein kinase 3 (HIPK3), transcript variant 1, mGFP tagged |
CNY 14,060.00 |
|
| RC214196L3 | Lenti ORF clone of Human homeodomain interacting protein kinase 3 (HIPK3), transcript variant 1, Myc-DDK-tagged |
CNY 14,060.00 |
|
| RC214196L4 | Lenti ORF clone of Human homeodomain interacting protein kinase 3 (HIPK3), transcript variant 1, mGFP tagged |
CNY 14,060.00 |
|
| RG214196 | HIPK3 (tGFP-tagged) - Human homeodomain interacting protein kinase 3 (HIPK3), transcript variant 1 |
CNY 13,400.00 |
|
| SC323551 | HIPK3 (untagged)-Kinase deficient mutant (K226M) of Human homeodomain interacting protein kinase 3 (HIPK3), transcript variant 1 |
CNY 8,464.00 |
