FREM1 (BC031064) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	C9orf143; C9orf145; C9orf154; extracellular matrix protein QBRICK; FLJ25461; FRAS1 related extracellular matrix 1; fras1 related extracellular matrix protein 1; OTTHUMP00000021061; OTTHUMP00000044926; QBRICK; RP11-439N12.3
Vector	pCMV6 series
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for BC031064, the custom clone sequence may differ by one or more nucleotides ATGCTGAAGGCTGCCTTGCCTCTCTTTACCAGATTCATCATCAGCAATGGACTGCGGACC GAGCACGGGGTGTTTGAGATCACACTGGAGACTGTGGACAGAGCCCTGCCTGTGGTAACC AGGAACAAGGGGTTGAGACTGGCCCAAGGGGCCGTGGGCCTGCTTTCCCCTGACCTCCTT CAGCTGACCGACCCTGATACACCTGCGGAGAACCTCACCTTCCTCTTGGTTCAGCTCCCC CAGCATGGCCAGCTCTACCTGTGGGGGACAGGGCTACTTCAACACAATTTCACCCAGCAG GATGTGGACAGCAAGAATGTGGCCTATCGGCACTCAGGAGGGGACTCCCAGACTGACTGC TTTACTTTCATGGCCACAGACGGGACAAACCAAGGCTTTATTGTGAATGGGAGAGTGTGG GAAGAACCTGTTTTATTCACCATTCAGGTAGACCAATTGGACAAAACAGCTCCTCGTATC ACACTCTTGCATTCCCCTTCTCAAGTGGGGCTCCTGAAAAATGGCTGCTACGGGATTTAC ATCACTTCCCGCGTGTTGAAGGCATCAGACCCTGACACTGAGGACGATCAGATCATCTTT AAAATTCTACAAGGCCCAAAACATGGACATCTGGAGAACACAACAACAGGTGAATTTATC CATGAGAAATTTAGCCAAAAGGACTTAAACAGTAAGACTATTCTTTACATCATAAACCCA TCTTTGGAAGTAAATTCAGATACCGTGGAATTTCAAATCATGGACCCCACAGGGAACTCG GCCACTCCTCAAAATTTGGAACTGAAGTGGTCTCATATTGAATGGTCACAGACCGAATAT GAAGTCTGTGAGAATGTGGGTTTGTTGCCCTTGGAAATTATCAGAAGGGGATATTCCATG GACTCGGCCTTTGTGGGTATAAAGGTCAACCAAGTGTCAGCTGCAGTTGGAAAAGATTTC ACCGTGATTCCATCTAAACTGATTCAGTTTGACCCAGGAATGTCAACTAAGATGTGGAAT ATAGCAATTACCTATGACGGATTAGAGGAAGATGATGAGGTCTTTGAAGTAATTCTGAAC TCCCCTGTGAATGCAGTTCTTGGCACAAAGACAAAAGCTGCAGTGAAAATTTTGGACTCA AAAGGAGGACAATGCCATCCTTCATATTCCTCCAACCAAAGCAAGCACAGCACATGGGAG AAGGGCATTTGGCATCTGCTGCCCCCAGGGTCTTCCTCATCCACCACTTCTGGTTCCTTT CATCTGGAAAGAAGACCTCTTCCATCCTCCATGCAGCTAGCAGTCATCAGGGGAGACACC CTGCGGGGCTTTGATTCTACAGATCTTTCTCAAAGGAAGCTTAGGACCCGTGGGAATGGC AAAACAGTTCGTCCATCCTCTGTTTATAGAAATGGAACAGACATCATCTATAATTATCAT GGGATAGTTTCCTTGAAACTGGAGGATGACAGTTTCCCAACTCACAAAAGGAAGGCCAAA GTATCCATCATTAGTCAGCCACAAAAGACAATCAAAGTGGCAGAACTGCCTCAAGCAGAT AAGGTGGAATCCACAACTGACTCACACTTCCCCAGACAGGACCAGTTGCCCTCATTTCCA AAGAACTGCACTCTGGAATTAAAGGGACTCTTCCATTTTGAAGAAGGCATCCAGAAGCTG TATCAGTGCAATGGGATCGCCTGGAAAGCCTGGAGTCCCCAAACCAAGGATGTGGAAGAC AAATCCTGTCCAGCCGGGTGGCACCAGCACTCAGGCTACTGTCACATCTTGATCACAGAG CAGAAAGGCACCTGGAATGCGGCTGCCCAAGCTTGCAGGGAACAATACCTGGGCAACCTT GTAACTGTATTCTCCAGGCAGCACATGCGGTGGCTCTGGGACATTGGTGGGAGAAAGTCC TTTTGGATAGGTTTGAACGACCAAGTGCATGCTGGCCACTGGGAGTGGATCGGTGGTGAA CCTGTTGCCTTCACCAATGGGAGAAGAGGGCCCTCTCCACGCTCCAAGCTTGGAAAGAGC TGTGTTTTGGTTCAAAGACAAGGGAAATGGCAAACAAAAGACTGTAGGAGAGCCAAACCT CATAATTATGGGTGTTCCAGAAAACTC
Restriction Sites	Please inquire
ACCN	BC031064
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC031064.1, AAH31064.2
RefSeq Size	2439 bp
RefSeq ORF	2439 bp
Locus ID	158326
Domains	CLECT, Calx-beta
Protein Families	Protease, Transmembrane
Gene Summary	This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation. [provided by RefSeq, Apr 2011]

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