FREM1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 0.5 - 1 ug/mL, ICC: 20 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	FREM1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human FREM1.
Formulation	FREM1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	FREM1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	FRAS1 related extracellular matrix 1
Database Link	NP_659403 Entrez Gene 329872 MouseEntrez Gene 158326 Human UniProt ID Q5H8C1
Background	FREM1 Antibody: FREM1 is a member of the FRAS1-related extracellular matrix protein family and is thought to play a role in craniofacial and renal development. FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. It is recognized by cells in the embryonic skin and hair follicles through different members of the integrin family. Deficiency in the Fras1/Frem genes gives rise to the bleb phenotype, which is equivalent to the human hereditary disorder Fraser syndrome.
Synonyms	BNAR; C9orf143; C9orf145; C9orf154; MOTA; TILRR; TRIGNO2
Reference Data
Protein Families	Protease, Transmembrane

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