Histidine decarboxylase (HDC) (NM_002112) Human Untagged Clone
CAT#: SC314351
HDC (untagged)-Human histidine decarboxylase (HDC)
CNY 7,896.00
Cited in 2 publications. |
Product images
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Restriction Sites | SgfI-MluI |
ACCN | NM_002112 |
Insert Size | 1989 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_002112.3 |
RefSeq Size | 2646 bp |
RefSeq ORF | 1989 bp |
Locus ID | 3067 |
UniProt ID | P19113 |
Domains | pyridoxal_deC |
Protein Families | Druggable Genome |
Protein Pathways | Histidine metabolism, Metabolic pathways |
MW | 74.1 kDa |
Gene Summary | This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
---|
Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation
,null,
Journal of the American Chemical Society
,PubMed ID 31017395
[HDC]
|
Dysfusion Transcriptional Control of Drosophila Tracheal Migration, Adhesion, and Fusion
,Lan Jiang and Stephen T. Crews,
Mol. Cell. Biol.Sep 2006; 26: 6547 - 6556.
[HDC]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
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RG212698 | HDC (tGFP-tagged) - Human histidine decarboxylase (HDC) |
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