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hnRNP L (HNRNPL) (NM_001533) Human Untagged Clone
CAT＃: SC314118
HNRNPL (untagged)-Human heterogeneous nuclear ribonucleoprotein L (HNRNPL), transcript variant 1
CNY 6,592.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | hnRNP-L; HNRPL; P/OKcl.14 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001533 edited
TCTGCGCCGCCATGTCGCGGAGGCTGCTGCCCCGGGCGGAGAAGCGGCGTCGGCGGCTGG AGCAGAGGCAGCAGCCGGACGAGCAGCGGAGGCGGTCGGGAGCGATGGTGAAGATGGCGG CGGCGGGCGGCGGAGGCGGCGGTGGCCGCTACTACGGCGGCGGCAGTGAGGGCGGCCGGG CCCCTAAGCGGCTCAAGACTGACAACGCCGGCGACCAGCACGGAGGCGGCGGCGGTGGCG GTGGAGGAGCCGGGGCGGCGGGCGGCGGCGGCGGTGGGGAGAACTACGATGACCCGCACA AAACCCCTGCCTCCCCAGTTGTCCACATCAGGGGCCTGATTGACGGTGTGGTGGAAGCAG ACCTTGTGGAGGCCTTGCAGGAGTTTGGACCCATCAGCTATGTGGTGGTAATGCCTAAAA AGAGACAAGCACTGGTGGAGTTTGAAGATGTGTTGGGGGCTTGCAACGCAGTGAACTACG CAGCCGACAACCAAATATACATTGCTGGTCACCCAGCTTTTGTCAACTACTCTACCAGCC AGAAGATCTCCCGCCCTGGGGACTCGGATGACTCCCGGAGCGTGAACAGTGTGCTTCTCT TTACCATCCTGAACCCCATTTATTCGATCACCACGGATGTTCTTTACACTATCTGTAATC CTTGTGGCCCTGTCCAGAGAATTGTCATTTTCAGGAAGAATGGAGTTCAGGCGATGGTGG AATTTGACTCAGTTCAAAGTGCCCAGCGGGCCAAGGCCTCTCTCAATGGGGCTGATATCT ATTCTGGCTGTTGCACTCTGAAGATCGAATACGCAAAGCCTACACGCTTGAATGTGTTCA AGAATGATCAGGATACTTGGGACTACACAAACCCCAATCTCAGTGGACAAGGTGACCCTG GCAGCAACCCCAACAAACGCCAGAGGCAGCCCCCTCTCCTGGGAGATCACCCCGCAGAAT ATGGAGGGCCCCACGGTGGGTACCACAGCCATTACCATGATGAGGGCTACGGGCCCCCCC CACCTCACTACGAAGGGAGAAGGATGGGTCCACCAGTGGGGGGTCACCGTCGGGGCCCAA GTCGCTACGGCCCCCAGTATGGGCACCCCCCACCCCCTCCCCCACCACCCGAGTATGGCC CTCACGCCGACAGCCCTGTGCTCATGGTCTATGGCTTGGATCAATCTAAGATGAACTGTG ACCGAGTCTTCAATGTCTTCTGCTTATATGGCAATGTGGAGAAGGTGAAATTCATGAAAA GCAAGCCGGGGGCCGCCATGGTGGAGATGGCTGATGGCTACGCTGTAGACCGGGCCATTA CCCACCTCAACAACAACTTCATGTTTGGGCAGAAGCTGAATGTCTGTGTCTCCAAGCAGC CAGCCATCATGCCTGGTCAGTCATACGGGTTGGAAGACGGGTCTTGCAGTTACAAAGACT TCAGTGAATCCCGGAACAATCGGTTCTCCACCCCAGAGCAGGCAGCCAAGAACCGCATCC AGCACCCCAGCAACGTGCTGCACTTCTTCAACGCCCCGCTGGAGGTGACCGAGGAGAACT TCTTTGAGATCTGCGATGAGCTGGGAGTGAAGCGGCCATCTTCTGTGAAAGTATTCTCAG GCAAAAGTGAGCGCAGCTCCTCTGGACTGCTGGAGTGGGAATCCAAGAGCGATGCCCTGG AGACTCTGGGCTTCCTGAACCATTACCAGATGAAAAACCCAAATGGTCCATACCCTTACA CTCTGAAGTTGTGTTTCTCCACTGCTCAGCACGCCTCCTAATTAGGTGCCTAGGAAGAGT CCCATCTGAGCAGGAAGACATTTCTCTTTCCTTTATGCCATTTTTTGTTTTTGTTATTTG CAAAAGATCTTGTATTCCTTTTTTTTTTTTTTTTTTTTTTTTTTAAATGCTAGGTTTGTA GAGGCTTACTTAACCTTAATGGAAACGCTGGAAATCTGCAGGGGGAGGGAGAGGGGAACT GTTATCTCCCAAGATTAACCTTCACTTTTAAAAAATTATTGGACATGTGATTTTTTTTTT TCCTGTTCAAACATTTGTGCTGCCCATGTACTCTTGGCACATTTCAATAAAATTGTTTGG AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_001533 unedited
GACAGAATTTGTAATACGACTCACTATAGGGGCGGCCGCGAATTCGCACGAGGCTGCGCC GCCATGTCGCGGAGGCTGCTGCCCCGGGCGGAGAAGCGGCGTCGGCGGCTGGAGCAGAGG CAGCAGCCGGACGAGCAGCGGAGGCGGTCGGGAGCGATGGTGAAGATGGCGGCGGCGGGC GGCGGAGGCGGCGGTGGCCGCTACTACGGCGGCGGCAGTGAGGGCGGCCGGGCCCCTAAG CGGCTCAAGACTGACAACGCCGGCGACCAGCACGGAGGCGGCGGCGGTGGCGGTGGAGGA GCCGGGGCGGCGGGCGGCGGCGGCGGTGGGGAGAACTACGATGACCCGCACAAAACCCCT GCCTCCCCAGTTGTCCACATCAGGGGCCTGATTGACGGTGTGGTGGAAGCAGACCTTGTG GAGGCCTTGCAGGAGTTTGGACCCATCAGCTATGTGGTGGTAATGCCTAAAAAGAGACAA GCACTGGTGGAGTTTGAAGATGTGTTGGGGGCTTGCAACGCAGTGAACTACGCAGCCGAC AACCAAATATACATTGCTGGTCACCCAGCTTTTGTCAACTACTCTACCAGCCAGAAGATC TCCCGCCCTGGGGACTCGGATGACTCCCGGAGCGTGAACAGTGTGCTTCTCTTTACCATC CTGAACCCCATTTATTCGATCACCACGGATGTTCTTTACACTATCTGTAATCCTTGTGGG CCCTGTCCAGAGAATTGTCATTTTCAGGAAGAATGGAGTTCAGGCGATGGTGGGAATTTG ACTCCTTTCAAAGTGCCCCAGCGGGCCCAAGCCTTTCTCAATGGGGCTGATATCTT >OriGene 3' read for NM_001533 unedited
CACTTGGAGATGGCAACTTCCAGGNCCAGNANGAGCACTGGGGNGGGGTCACAGGGATGC CACCCGGGATCTGTTCNAGAAACAGCTTGACCGCAGCCGCAATCTANAGTCGAGTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCCAAAC AATTTTTTTGAAATGGGCCAAGAGTTCATGGGCCGCCCAATTGTTTGAACCGGAAAAAAA AAAATCCCCTGTTCAATTTTTTTTTAAAAGTGAAGGTTAATTTTGGGAGAAAACAGTTNN CNTCTCCCTCCCCCTGGAAATTTCCAGGGTTTCCATTAAGGGTAAATAAGCCTTTTCAAA CCTNNCTTTTTNAAAAAAAAAAAAAAAAAAAAAAGGGGTTTCCAGTTTTTTTGCCAATAA CAAAAACAAAAAATGGCTTTAAGGAAAAAAAAATGTTTTTCTGCTCAAATGGGACTTTTT CTAGGCCCCTTATTTAGAGGCGTGCTTAACATTGGAGAAACACAACTTCAAAGTGTAAAG GTATGGGACCTTGTGGGTTCCAACTTGGGTATGGTTTCAAGCNGCCTATTTTCTGAGGCA TTGTTTTGGAATTCCCACTCCAGCAGTTCAGAGGAGCTGCGCTCACTTTTTGCTGAGAAT CTTTCACAGGAGTGGCCGCTTTACTCCCGCTTATGGGAGATTTTAGAGGGTTTTCCTTGG TCACCTCCGCGGGGCGTTTAGAAAGATGCAACACTTTTTTGGGGTGCTGGATGGCGTTTT TGGCTGCCTGCTTTGGGGGGGAAACCCCATTTTTCCCGGGTTCACTGGATTTTTTTGTCA CGGGC |
| Restriction Sites | Please inquire |
| ACCN | NM_001533 |
| Insert Size | 2200 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001533.2, NP_001524.2 |
| RefSeq Size | 2129 bp |
| RefSeq ORF | 1770 bp |
| Locus ID | 3191 |
| UniProt ID | P14866 |
| Domains | RRM |
| Gene Summary | Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Separate cis-trans Pathways Post-transcriptionally Regulate Murine CD154 (CD40 Ligand) Expression: A NOVEL FUNCTION FOR CA REPEATS IN THE 3'-UNTRANSLATED REGION
,B. JoNell Hamilton, Xiao-Wei Wang, Jane Collins, Donald Bloch, Alan Bergeron, Brian Henry, Benjamin M. Terry, Moe Zan, Andrew J. Mouland, and William F. C. Rigby,
J. Biol. Chem., Sep 2008; 283: 25606 - 25616
[HNRNPL]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219240 | HNRNPL (Myc-DDK-tagged)-Human heterogeneous nuclear ribonucleoprotein L (HNRNPL), transcript variant 1 |
CNY 6,576.00 |
|
| RC219240L1 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein L (HNRNPL), transcript variant 1, Myc-DDK-tagged |
CNY 8,976.00 |
|
| RC219240L2 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein L (HNRNPL), transcript variant 1, mGFP tagged |
CNY 6,460.00 |
|
| RC219240L3 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein L (HNRNPL), transcript variant 1, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC219240L4 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein L (HNRNPL), transcript variant 1, mGFP tagged |
CNY 6,460.00 |
|
| RG219240 | HNRNPL (tGFP-tagged) - Human heterogeneous nuclear ribonucleoprotein L (HNRNPL), transcript variant 1 |
CNY 8,176.00 |
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