MAP4 (AK054696) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Vector	pCMV6 series
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for AK054696, the custom clone sequence may differ by one or more nucleotides ATGTCGCTCTCAGACAAGCAGACAGCCTCTCTCACTGCCGCGTACGGTCAGCTCAGTAAG GGCAAGCCTGCAGAGTGCCGAATGGACTCCCCAAAAGAAATCAGTCAAGCCGGATTCGAA TGGCAGAGGACAGAGGGCAAACTGAATGAAATTGGGCTGAATGTCAGCATGGACGGGCAA CCAAAAGATGGGCTTGTGAAGAATGCCAGCTTCCTGGAGCAGAACAAGCTCTGCTTTTTT GAGGGGAAGCTAGACAAAGAGCTGAGCATTGAAATGCAGGACAAGGACTGTCAAGAAGCC TCAGGTCACCTTGAGAGCAGGTATGTGATTTCAGAGACCTGCCATCCCTTGGAGGGGAAC TCGGTACACCAGAAGACCTCCGAGTTCCATCTGGGACTCATAGAGGGGCCAGACAAAAAC AAAACCATTCCAGTTCAGGGGAAGGTGGCAGGGAAGAATGGACTAGAGACCAAGAGCCAG TCAGATCTGGATTTCCCTGGGGCTGCTGACATCCCTACCAGATATGTTAAGGAGCAGGAA ACCAGTGTTTGGAACCCCAGCTTTCATCCAGTGGCTCAAGGCTCTCTGGGCTCAAGGGAA GCAACTCCGGGAGAGATGGAGAATAGCATCACCCCTGGCTGCCCAGTGATTGGGGTGGTA AATGATAACTCTGAGCAGCTGAAGTGTGAGTCCCCACTCCTGGTGTCTCTAGCCCACCCA GCCCCCATTATTGAGCATTCACCCACCACCATTCCGCCAATCACTATGGTGTTCACCCAG GAACATTTGAATGCAAGCTGTCACATCAGAGACCATGATAAGGAGTTGGAGAAATTGAGT TCTACCGAGGAGGCTGTGCTCAACCAAGCCCCCCAGCAGAAAAAGGCAGTGCGCAGGGCC CTGTCTGAATGTTCTCACCTCTCAGTTCCCCCAGCTGTCAACCTTGCAGATAAGTACCCT GAACTCCCTGCCCGAGAAGAGCCTTCTTCTGGCCTGCTGCCTCCCCCTAGTAGCCCAATG CCTAGTCCTACACCTGGGAAACTGGGAGCTCCTGCTATGAAGCGCTCCATGACTGTGGGT GAGGAACAGACAGCTAGCTACAAATTGAGCCCTGGGAAACTGCCCATCTTGTCTACTAAA GAGATACCTCCTTTCATCTGTGAGGAACCAGTGGCCAAGAAGAGAGAAGAATTGGCTCAC TTCAGCAACAGCAGCAGCAACTCTGGGAAGAAGGAACTCGGCACTGCTGGATTATATCTC CATAGTAAGCTGGAGCAGATTCCTGAAGGAAGCAGCAAGGAAAAAGGGCAGGAAGATTTT AGTGAAACTAGAATTGATTCATGCTCGCAGGTTTGCCAGCGAGGAGAGAAACAGCCAGGA CAGACGGCTCTGGCAGGGAAGAAAGAAATTGAGGTCACTGCAACCCAGAGCACTCCATCG TTCCTGTTTGAAAAGCCCCCACGTGATGGAATAGCCAGGCCAGAAGAAGGAAGGCCTGTG GTGAGTGGGACAGGAAATGACATCACCACCCCACCGAACAAGGAGCTCCCACCAAGCCCA GAGAAGAAAACAAAGGTAGGTGCCAGAATGGTGGTTATCTTCTACTGCCATAATTTT
Restriction Sites	Please inquire
ACCN	AK054696
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	AK054696.1, BAB70795.1
RefSeq Size	2156 bp
RefSeq ORF	1620 bp
Locus ID	4134
Gene Summary	The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

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