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HEY1 (NM_001040708) Human Untagged Clone
CAT＃: SC311179
HEY1 (untagged)-Human hairy/enhancer-of-split related with YRPW motif 1 (HEY1), transcript variant 2
CNY 3,600.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BHLHb31; CHF2; HERP2; HESR1; hHRT1; HRT-1; NERP2; OAF1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001040708 edited
GAGGCAAAGCGTGAGCGGGATCAGTGTGTGCGGAACGCAAGCAGCCGAGAGCGGAGAGGC GCCGCTGTAGTTAACTCCTCCCTGCCCGCCGCGCCGACCCTCCCCAGGAACCCCCAGGGA GCCAGCATGAAGCGAGCTCACCCCGAGTACAGCTCCTCGGACAGCGAGCTGGACGAGACC ATCGAGGTGGAGAAGGAGAGTGCGGACGAGAATGGAAACTTGAGTTCGGCTCTAGGTTCC ATGTCCCCAACTACATCTTCCCAGATTTTGGCCAGAAAAAGACGGAGAGGAATAATTGAG AAGCGCCGACGAGACCGGATCAATAACAGTTTGTCTGAGCTGAGAAGGCTGGTACCCAGT GCTTTTGAGAAGCAGGTAATGGAGCAAGGATCTGCTAAGCTAGAAAAAGCCGAGATCCTG CAGATGACCGTGGATCACCTGAAAATGCTGCATACGGCAGGAGGGAAAGGTTACTTTGAC GCGCACGCCCTTGCTATGGACTATCGGAGTTTGGGATTTCGGGAATGCCTGGCAGAAGTT GCGCGTTATCTGAGCATCATTGAAGGACTAGATGCCTCTGACCCGCTTCGAGTTCGACTG GTTTCGCATCTCAACAACTACGCTTCCCAGCGGGAAGCCGCGAGCGGCGCCCACGCGGGC CTCGGACACATTCCCTGGGGGACCGTCTTCGGACATCACCCGCACATCGCGCACCCGCTG TTGCTGCCCCAGAACGGCCACGGGAACGCGGGCACCACGGCCTCACCCACGGAACCGCAC CACCAGGGCAGGCTGGGCTCGGCACATCCGGAGGCGCCTGCTTTGCGAGCGCCCCCTAGC GGCAGCCTCGGACCGGTGCTCCCTGTGGTCACCTCCGCCTCCAAACTGTCGCCGCCTCTG CTCTCCTCAGTGGCCTCCCTGTCGGCCTTCCCCTTCTCTTTCGGCTCCTTCCACTTACTG TCTCCCAATGCACTGAGCCCTTCAGCACCCACGCAGGCTGCAAACCTTGGCAAGCCCTAT AGACCTTGGGGGACGGAGATCGGAGCTTTTTAAAGAACTGATGTAGAATGAGGGAGGGGA AAGTTTAAAATCCCAGCTGGGCTGGACTGTTGCCAACATCACCTTAAAGTCGTCAGTAAA AGTAAAAAGGAAAAAGGTACACTTTCAGATAATTTTTTTTTTAAAGACTAAAGGTTTGTT GGTTTACTTTTATCTTTTTTAATGTTTTTTTCATCATGTCATGTATTAGCAGTTTTTAAA AACTAGTTGTTAAATTTTGTTCAAGACATTAAATTGAAATAGTGAGTATAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_001040708 unedited
CTACACATTTGTACACGACTTACTACTAGGGCGGCCGCGAACTCGGCACGAGGCAAAGCG TGAGCGGGATCAGTGTGTGCGGAACGCAAGCAGCCGAGAGCGGAGAGGCGCCGCTGTAGT TAACTCCTCCCTGCCCGCCGCGCCGACCCTCCCCAGGAACCCCCAGGGAGCCAGCATGAA GCGAGCTCACCCCGAGTACAGCTCCTCGGACAGCGAGCTGGACGAGACCATCGAGGTGGA GAAGGAGAGTGCGGACGAGAATGGAAACTTGAGTTCGGCTCTAGGTTCCATGTCCCCAAC TACATCTTCCCAGATTTTGGCCAGAAAAAGACGGAGAGGAATAATTGAGAAGCGCCGACG AGACCGGATCAATAACAGTTTGTCTGAGCTGAGAAGGCTGGTACCCAGTGCTTTTGAGAA GCAGGTAATGGAGCAAGGATCTGCTAAGCTAGAAAAAGCCGAGATCCTGCAGATGACCGT GGATCACCTGAAAATGCTGCATACGGCAGGAGGGAAAGGTTACTTTGACGCGCACGCCCT TGCTATGGACTATCGGAGTTTGGGATTTCGGGAATGCCTGGCAGAAGTTGCGCGTTATCT GAGCATCATTGAAGGACTAGATGCCTCTGACCCGCTTCGAGTTCGACTGGTTTCGCATCT CAACAACTACGCTTCCCAGCGGGAAGCCGCGAGCGGCGCCCACGCGGGCCTCGGACACAT TCCCTGGGGGACCGTCTTCGGACATCACCCGCACATCGCGCACCCGCTGTTGCTGCCCCA GAACGGCCCACGGGAACGCGGGCACCACGGCCTCACCCACGGAACCCGCACCACCAGGGC AGGCTGGGCTCGGCACATCCGGAGGCGCCTGCTTTGCGAGCGCCCCTAGCGCAGCCTCGA CCGTGCTCCCTGTGGTCACCTCCGCCTCAAACTGTCGCCGCCTCTGCTCTCTCAGTGGCC TCCCTGTCGGCTTCCCCTTTCTCTTTCGGCTCCTTCCACTA |
| Restriction Sites | Please inquire |
| ACCN | NM_001040708 |
| Insert Size | 1400 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001040708.1, NP_001035798.1 |
| RefSeq Size | 2331 bp |
| RefSeq ORF | 927 bp |
| Locus ID | 23462 |
| UniProt ID | Q9Y5J3 |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2), also known as HESR1-12nt, uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in a longer protein (isoform b). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Identification and characterization of regulatory elements in the promoter of ACVR1, the gene mutated in Fibrodysplasia Ossificans Progressiva
,Giacopelli, F;Cappato, S;Tonachini, L;Mura, M;Di Lascio, S;Fornasari, D;Ravazzolo, R;Bocciardi, R;,
Orphanet J Rare Dis. 2013 Sep 18;8(1):145
,PubMed ID 24047559
[HEY1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216696 | HEY1 (Myc-DDK-tagged)-Human hairy/enhancer-of-split related with YRPW motif 1 (HEY1), transcript variant 2 |
CNY 3,600.00 |
|
| RC216696L1 | Lenti ORF clone of Human hairy/enhancer-of-split related with YRPW motif 1 (HEY1), transcript variant 2, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC216696L2 | Lenti ORF clone of Human hairy/enhancer-of-split related with YRPW motif 1 (HEY1), transcript variant 2, mGFP tagged |
CNY 6,000.00 |
|
| RC216696L3 | Lenti ORF clone of Human hairy/enhancer-of-split related with YRPW motif 1 (HEY1), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC216696L4 | Lenti ORF clone of Human hairy/enhancer-of-split related with YRPW motif 1 (HEY1), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG216696 | HEY1 (tGFP-tagged) - Human hairy/enhancer-of-split related with YRPW motif 1 (HEY1), transcript variant 2 |
CNY 5,200.00 |
