CACNA1C (NM_000719) Human Untagged Clone

CAT#: SC311130

CACNA1C (untagged)-Human calcium channel, voltage-dependent, L type, alpha 1C subunit (CACNA1C), transcript variant 18



  "NM_000719" in other vectors (3)

CNY 21,184.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
Mouse Monoclonal anti-CACNA1C Antibody
    • 100 ug

CNY 5,830.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms CACH2; CACN2; CACNL1A1; CaV1.2; CCHL1A1; LQT8; TS; TS. LQT8
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_000719 edited
TCTTCGTGGCTGCTCCTCCTATTAAAACCATTTTTGGTCCATGGTCAATGAGAATACGAG
GATGTACATTCCAGAGGAAAACCACCAAGGTTCCAACTATGGGAGCCCACGCCCCGCCCA
TGCCAACATGAATGCCAATGCGGCAGCGGGGCTGGCCCCTGAGCACATCCCCACCCCGGG
GGCTGCCCTGTCGTGGCAGGCGGCCATCGACGCAGCCCGGCAGGCTAAGCTGATGGGCAG
CGCTGGCAATGCGACCATCTCCACAGTCAGCTCCACGCAGCGGAAGCGGCAGCAATATGG
GAAACCCAAGAAGCAGGGCAGCACCACGGCCACACGCCCGCCCCGAGCCCTGCTCTGCCT
GACCCTGAAGAACCCCATCCGGAGGGCCTGCATCAGCATTGTCGAATGGAAACCATTTGA
AATAATTATTTTACTGACTATTTTTGCCAATTGTGTGGCCTTAGCGATCTATATTCCCTT
TCCAGAAGATGATTCCAACGCCACCAATTCCAACCTGGAACGAGTGGAATATCTCTTTCT
CATAATTTTTACGGTGGAAGCGTTTTTAAAAGTAATCGCCTATGGACTCCTCTTTCACCC
CAATGCCTACCTCCGCAACGGCTGGAACCTACTAGATTTTATAATTGTGGTTGTGGGGCT
TTTTAGTGCAATTTTAGAACAAGCAACCAAAGCAGATGGGGCAAACGCTCTCGGAGGGAA
AGGGGCCGGATTTGATGTGAAGGCGCTGAGGGCCTTCCGCGTGCTGCGCCCCCTGCGGCT
GGTGTCCGGAGTCCCAAGTCTCCAGGTGGTCCTGAATTCCATCATCAAGGCCATGGTCCC
CCTGCTGCACATCGCCCTGCTTGTGCTGTTTGTCATCATCATCTACGCCATCATCGGCTT
GGAGCTCTTCATGGGGAAGATGCACAAGACCTGCTACAACCAGGAGGGCATAGCAGATGT
TCCAGCAGAAGATGACCCTTCCCCTTGTGCGCTGGAAACGGGCCACGGGCGGCAGTGCCA
GAACGGCACGGTGTGCAAGCCCGGCTGGGATGGTCCCAAGCACGGCATCACCAACTTTGA
CAACTTTGCCTTCGCCATGCTCACGGTGTTCCAGTGCATCACCATGGAGGGCTGGACGGA
CGTGCTGTACTGGGTCAATGATGCCGTAGGAAGGGACTGGCCCTGGATCTATTTTGTTAC
ACTAATCATCATAGGGTCATTTTTTGTACTTAACTTGGTTCTCGGTGTGCTTAGCGGAGA
GTTTTCCAAAGAGAGGGAGAAGGCCAAGGCCCGGGGAGATTTCCAGAAGCTGCGGGAGAA
GCAGCAGCTAGAAGAGGATCTCAAAGGCTACCTGGATTGGATCACTCAGGCCGAAGACAT
CGATCCTGAGAATGAGGACGAAGGCATGGATGAGGAGAAGCCCCGAAACATGAGCATGCC
CACCAGTGAGACCGAGTCCGTCAACACCGAAAACGTGGCTGGAGGTGACATCGAGGGAGA
AAACTGCGGGGCCAGGCTGGCCCACCGGATCTCCAAGTCAAAGTTCAGCCGCTACTGGCG
CCGGTGGAATCGGTTCTGCAGAAGGAAGTGCCGCGCCGCAGTCAAGTCTAATGTCTTCTA
CTGGCTGGTGATTTTCCTGGTGTTCCTCAACACGCTCACCATTGCCTCTGAGCACTACAA
CCAGCCCAACTGGCTCACAGAAGTCCAAGACACGGCAAACAAGGCCCTGCTGGCCCTGTT
CACGGCAGAGATGCTCCTGAAGATGTACAGCCTGGGCCTGCAGGCCTACTTCGTGTCCCT
CTTCAACCGCTTTGACTGCTTCGTCGTGTGTGGCGGCATCCTGGAGACCATCCTGGTGGA
GACCAAGATCATGTCCCCACTGGGCATCTCCGTGCTCAGATGCGTCCGGCTGCTGAGGAT
TTTCAAGATCACGAGGTACTGGAACTCCTTGAGCAACCTGGTGGCATCCTTGCTGAACTC
TGTGCGCTCCATCGCCTCCCTGCTCCTTCTCCTCTTCCTCTTCATCATCATCTTCTCCCT
CCTGGGGATGCAGCTCTTTGGAGGAAAGTTCAACTTTGATGAGATGCAGACCCGGAGGAG
CACATTCGATAACTTCCCCCAGTCCCTCCTCACTGTGTTTCAGATCCTGACCGGGGAGGA
CTGGAATTCGGTGATGTATGATGGGATCATGGCTTATGGCGGCCCCTCTTTTCCAGGGAT
GTTAGTCTGTATTTACTTCATCATCCTCTTCATCTGTGGAAACTATATCCTACTGAATGT
GTTCTTGGCCATTGCTGTGGACAACCTGGCTGATGCTGAGAGCCTCACATCTGCCCAAAA
GGAGGAGGAAGAGGAGAAGGAGAGAAAGAAGCTGGCCAGGACTGCCAGCCCAGAGAAGAA
ACAAGAGTTGGTGGAGAAGCCGGCAGTGGGGGAATCCAAGGAGGAGAAGATTGAGCTGAA
ATCCATCACGGCTGATGGAGAGTCTCCACCCGCCACCAAGATCAACATGGATGACCTCCA
GCCCAATGAAAATGAGGATAAGAGCCCCTACCCCAACCCAGAAACTACAGGAGAAGAGGA
TGAGGAGGAGCCAGAGATGCCTGTCGGCCCTCGCCCACGACCACTCTCTGAGCTTCACCT
TAAGGAAAAGGCAGTGCCCATGCCAGAAGCCAGCGCGTTTTTCATCTTCAGCTCTAACAA
CAGGTTTCGCCTCCAGTGCCACCGCATTGTCAATGACACGATCTTCACCAACCTGATCCT
CTTCTTCATTCTGCTCAGCAGCATTTCCCTGGCTGCTGAGGACCCGGTCCAGCACACCTC
CTTCAGGAACCATATTCTGTTTTATTTTGATATTGTTTTTACCACCATTTTCACCATTGA
AATTGCTCTGAAGATGACTGCTTATGGGGCTTTCTTGCACAAGGGTTCTTTCTGCCGGAA
CTACTTCAACATCCTGGACCTGCTGGTGGTCAGCGTGTCCCTCATCTCCTTTGGCATCCA
GTCCAGTGCAATCAATGTCGTGAAGATCTTGCGAGTCCTGCGAGTACTCAGGCCCCTGAG
GGCCATCAACAGGGCCAAGGGGCTAAAGCATGTGGTTCAGTGTGTGTTTGTCGCCATCCG
GACCATCGGGAACATCGTGATTGTCACCACCCTGCTGCAGTTCATGTTTGCCTGCATCGG
GGTCCAGCTCTTCAAGGGAAAGCTGTACACCTGTTCAGACAGTTCCAAGCAGACAGAGGC
GGAATGCAAGGGCAACTACATCACGTACAAAGACGGGGAGGTTGACCACCCCATCATCCA
ACCCCGCAGCTGGGAGAACAGCAAGTTTGACTTTGACAATGTTCTGGCAGCCATGATGGC
CCTCTTCACCGTCTCCACCTTCGAAGGGTGGCCAGAGCTGCTGTACCGCTCCATCGACTC
CCACACGGAAGACAAGGGCCCCATCTACAACTACCGTGTGGAGATCTCCATCTTCTTCAT
CATCTACATCATCATCATCGCCTTCTTCATGATGAACATCTTCGTGGGCTTCGTCATCGT
CACCTTTCAGGAGCAGGGGGAGCAGGAGTACAAGAACTGTGAGCTGGACAAGAACCAGCG
ACAGTGCGTGGAATACGCCCTCAAGGCCCGGCCCCTGCGGAGGTACATCCCCAAGAACCA
GCACCAGTACAAAGTGTGGTACGTGGTCAACTCCACCTACTTCGAGTACCTGATGTTCGT
CCTCATCCTGCTCAACACCATCTGCCTGGCCATGCAGCACTACGGCCAGAGCTGCCTGTT
CAAAATCGCCATGAACATCCTCAACATGCTCTTCACTGGCCTCTTCACCGTGGAGATGAT
CCTGAAGCTCATTGCCTTCAAACCCAAGCACTATTTCTGTGATGCATGGAATACATTTGA
CGCCTTGATTGTTGTGGGTAGCATTGTTGATATAGCAATCACCGAGGTAAACCCAGCTGA
ACATACCCAATGCTCTCCCTCTATGAACGCAGAGGAAAACTCCCGCATCTCCATCACCTT
CTTCCGCCTGTTCCGGGTCATGCGTCTGGTGAAGCTGCTGAGCCGTGGGGAGGGCATCCG
GACGCTGCTGTGGACCTTCATCAAGTCCTTCCAGGCCCTGCCCTATGTGGCCCTCCTGAT
CGTGATGCTGTTCTTCATCTACGCGGTGATCGGGATGCAGGTGTTTGGGAAAATTGCCCT
GAATGATACCACAGAGATCAACCGGAACAACAACTTTCAGACCTTCCCCCAGGCCGTGCT
GCTCCTCTTCAGGTGTGCCACCGGGGAGGCCTGGCAGGACATCATGCTGGCCTGCATGCC
AGGCAAGAAGTGTGCCCCAGAGTCCGAGCCCAGCAACAGCACGGAGGGTGAAACACCCTG
TGGTAGCAGCTTTGCTGTCTTCTACTTCATCAGCTTCTACATGCTCTGTGCCTTCCTGAT
CATCAACCTCTTTGTAGCTGTCATCATGGACAACTTTGACTACCTGACAAGGGACTGGTC
CATCCTTGGTCCCCACCACCTGGATGAGTTTAAAAGAATCTGGGCAGAGTATGACCCTGA
AGCCAAGGGTCGTATCAAACACCTGGATGTGGTGACCCTCCTCCGGCGGATTCAGCCGCC
ACTAGGTTTTGGGAAGCTGTGCCCTCACCGCGTGGCTTGCAAACGCCTGGTCTCCATGAA
CATGCCTCTGAACAGCGACGGGACAGTCATGTTCAATGCCACCCTGTTTGCCCTGGTCAG
GACGGCCCTGAGGATCAAAACAGAAGGGAACCTAGAACAAGCCAATGAGGAGCTGCGGGC
GATCATCAAGAAGATCTGGAAGCGGACCAGCATGAAGCTGCTGGACCAGGTGGTGCCCCC
TGCAGGTGATGATGAGGTCACCGTTGGCAAGTTCTACGCCACGTTCCTGATCCAGGAGTA
CTTCCGGAAGTTCAAGAAGCGCAAAGAGCAGGGCCTTGTGGGCAAGCCCTCCCAGAGGAA
CGCGCTGTCTCTGCAGGCTGGCTTGCGCACACTGCATGACATCGGGCCTGAGATCCGACG
GGCCATCTCTGGAGATCTCACCGCTGAGGAGGAGCTGGACAAGGCCATGAAGGAGGCTGT
GTCCGCTGCTTCTGAAGATGACATCTTCAGGAGGGCCGGTGGCCTGTTCGGCAACCACGT
CAGCTACTACCAAAGCGACGGCCGGAGCGCCTTCCCCCAGACCTTCACCACTCAGCGCCC
GCTGCACATCAACAAGGCGGGCAGCAGCCAGGGCGACACTGAGTCGCCATCCCACGAGAA
GCTGGTGGACTCCACCTTCACCCCGAGCAGCTACTCGTCCACCGGCTCCAACGCCAACAT
CAACAACGCCAACAACACCGCCCTGGGTCGCCTCCCTCGCCCCGCCGGCTACCCCAGCAC
GGTCAGCACTGTGGAGGGCCACGGGCCCCCCTTGTCCCCTGCCATCCGGGTGCAGGAGGT
GGCGTGGAAGCTCAGCTCCAACAGGTGCCACTCCCGGGAGAGCCAGGCAGCCATGGCGGG
TCAGGAGGAGACGTCTCAGGATGAGATCTATGAAGTGAAGATGAACCATGACACGGAGGC
CTGCAGTGAGCCCAGCCTGCTCTCCACAGAGATGCTCTCCTACCAGGATGACGAAAATCG
GCAACTGACGCTCCCAGAGGAGGACAAGAGGGACATCCGGCAATCTCCGAAGAGGGGTTT
CCTCCGCTCTGCCTCACTAGGTCGAAGGGCCTCCTTCCACCTGGAATGTCTGAAGCGACA
GAAGGACCGAGGGGGAGACATCTCTCAGAAGACAGTCCTGCCCTTGCATCTGGTTCATCA
TCAGGCATTGGCAGTGGCAGGCCTGAGCCCCCTCCTCCAGAGAAGCCATTCCCCTGCCTC
ATTCCCTAGGCCTTTTGCCACCCCACCAGCCACACCTGGCAGCCGAGGCTGGCCCCCACA
GCCCGTCCCCACCCTGCGGCTTGAGGGGGTCGAGTCCAGTGAGAAACTCAACAGCAGCTT
CCCATCCATCCACTGCGGCTCCTGGGCTGAGACCACCCCCGGTGGCGGGGGCAGCAGCGC
CGCCCGGAGAGTCCGGCCCGTCTCCCTCATGGTGCCCAGCCAGGCTGGGGCCCCAGGGAG
GCAGTTCCACGGCAGTGCCAGCAGCCTGGTGGAAGCGGTCTTGATTTCAGAAGGACTGGG
GCAGTTTGCTCAAGATCCCAAGTTCATCGAGGTCACCACCCAGGAGCTGGCCGACGCCTG
CGACATGACCATAGAGGAGATGGAGAGCGCGGCCGACAACATCCTCAGCGGGGGCGCCCC
ACAGAGCCCCAATGGCGCCCTCTTACCCTTTGTGAACTGCAGGGACGCGGGGCAGGACCG
AGCCGGGGGCGAAGAGGACGCGGGCTGTGTGCGCGCGCGGGGTCGACCGAGTGAGGAGGA
GCTCCAGGACAGCAGGGTCTACGTCAGCAGCCTGTAGTGGGCGCTGCCAGATGCGGGCTT
TTTTTTATTTGTTTCAATGTTCCTAATGGGTTCGTTTCAGAAGTGCCTCACTGTTCTCGT
GACCTGGAGTTAACCGGAACAGCGTCTTCATTCATTTCTGTTGGGACCAGACGCGGAGCC
TGGGTGCGCGAGCCGCCCTCCGGGAGGAAGGCGCCCGGCTGCGTCTGCAGAGGCGGGGAG
AGGAGGCGGCGAGGGTCCCGGGGCGCGAGGAAGGCGCCTGCCCTCTCCCAGCTCGCAGGC
CCCGGGCCCGGCCGCGCCTCTGCGGGGAGAGCACCCCGGCTTCCCGCGCGCCCTCACCAA
AAGGACCCTACAGCAAACGGGTGTCTTTCGACTCTGCTTGTAGAAACCATTTGCACATAT
TCTGTACGAGCCTCGCTGTCTCCCTAGAGCCAGGGCCCTGCGGATTTGGAGAAGGGAGCG
GGGCAGGACTTCCAGGAGGACCCCAACCCGGCCCGGAGAGGGAGGAGGAGGCCTCCAGGG
GCGCGGAGCTCTGGGGATGGGCGTCGGGCCGGCAGTGGTGCGGCTCACTCCGTCCCTGCC
CACCTGCGACGGGATCCCCCGACCGGCACGGGCCACGCCGAGCTCCCGGCCAGCCGCCGG
CCCGCAGGCAGCGCGAGGGAGGAGCTGCGCCGCCGGGAAGGGGCCGCCGGCTCCGCCCAA
CCAGGTGGTGCTGAGCTTCCGCTGAGCGCTCTTTTGTTTTGTGGTTTGACACTTTTCTTG
ACAGCATGTTGCAGTTTCTTTTCGGTTTTGGTTTTTTTTAAATGTTTTATTTTGCTTTCC
CAGCGGGAGGGGAGGAAGAAGAGTGTTTACAAAGTCCTGTAGCCCCCTCACCTTTCTGTT
TTCACTTTTGCCAATGTACATCGGGTTTGGTTTTCTTGTATTATTTAAACGGTTGTGGTT
TCCTTTTTCCACGGAGGTTCAATAGAAGCCGCTGCAGGAGAGTTTTACCAACAAAAAAAA
AAAAAAAAAAAAAAAA
>OriGene 5' read for NM_000719 unedited
NCGTTTCCATTTGTATACGCACTTACTATAGGGCGGCCGCGATTCAGATCTGGTACCGAG
CTCGGATCCACTAGTAACGGCCGCCAGTGTGCTGGAATTCGCCCTTCTTCGTGGCTGCTC
CTCCTATTAAAACCATTTTTGGTCCATGGTCAATGAGAATACGAGGATGTACATTCCAGA
GGAAAACCACCAAGGTTCCAACTATGGGAGCCCACGCCCCGCCCATGCCAACATGAATGC
CAATGCGGCAGCGGGGCTGGCCCCTGAGCACATCCCCACCCCGGGGGCTGCCCTGTCGTG
GCAGGCGGCCATCGACGCAGCCCGGCAGGCTAAGCTGATGGGCAGCGCTGGCAATGCGAC
CATCTCCACAGTCAGCTCCACGCAGCGGAAGCGGCAGCAATATGGGAAACCCAAGAAGCA
GGGCAGCACCACGGCCACACGCCCGCCCCGAGCCCTGCTCTGCCTGACCCTGAAGAACCC
CATCCGGAGGGCCTGCATCAGCATTGTCGAATGGAAACCATTTGAAATAATTATTTTACT
GACTATTTTTGCCAATTGTGTGGCCTTAGCGATCTATATTCCCTTTCCAGAAGATGATTC
CAACGCCACCAATTCCAACCTGGAACGAGTGGAATATCTCTTTCTCATAATTTTTACGGT
GGAAGCGTTTTTAAAGTAATCGCCTATGGACTCCTCTTTCACCCCAATGCCTACCTCCGC
AACGGCTGGAACCTACTAGATTTTATAATTGTGGTTGTGGGGGCTTTTTAGTGCATTTTT
AGAACAAGCAACCCAAGCAGATGGGGCAAACGCTCTCCGAAGGAAAGGGGCCCGATTTGA
TGTGGAAGCGCTGGAGCCCTTCCGCGTGCTGGGCCCCCTGCGGCTGGTGTCCCGAGTC
>Forward primer walk for NM_000719 unedited
GCTTCTGGGCTGGACAACCCCCGTGGCGGGGGCAGCAGCGCCGCCCGGNANAGTCCGGCC
CGTCTCCCTCATGGTGCCCAGCCAGGCTGGGGCCCCAGGGAGGCAGTTCCACGGCAGTGC
CAGCAGCCTGGTGGAAGCGGTCTTGATTTCAGAAGGACTGGGGCAGTTTGCTCAAGATCC
CAAGTTCATCGAGGTCACCACCCAGGAGCTCGCCGACGCCTGCGACATGACCATAGAGGA
GATGGAGAGCGCGGCCGACAACATCCTCAGCGGGGGCGCCCCACAGAGCCCCAATGGCGC
CCTCTTACCCTTTGTGAACTGCAGGGACGCGGGGCAGGACCGAGCCGGGGGCGAAGAGGA
CGCGGGCTGTGTGCGCGCGCGGGGTCGACCGAGTGAGGAGGAGCTCCAGGACAGCAGGGT
CTACGTCAGCAGCCTGTAGTGGGCGCTGCCAGATGCGGGCTTTTTTTTATTTGTTTCAAT
GTTCCTAATGGGTTCGTTTCAGAAGTGCCTCACTGTTCTCGTGACCTGGAGTTAACCGGA
ACAGCGTCTTCATTCATTTCTGTTGGGACCAGACGCGGAGCCTGGGTGCGCGAGCCGCCC
TCCGGGAGGAAGGCGCCCGGCTGCGTCTGCAAAGGCGGNGAGAGGAGGCGGCGAGGGTCC
CGGGGCGCGAGGAAGGCGCCTGCCCTCTCCCAACTCGCAAGCCCCGGCCCGGGCCGCGCC
TCTGCGGGGAGAGCACCCCGGCTTCCGGGCGCCCTCACCAAAAGGACCCTACCGCAAACG
GGTGTCTTTCGCCTCTGCTTGTAGAAACCATTTGCACATATTCTGGACAAGCCTCGCTTG
TCTCCCCTAAAACCAGGGCCCTGGCGGTTTTGAAGAAAGGAACGGNGCAAGGCTTCCAGG
AAGACCCCC
Restriction Sites Please inquire     
ACCN NM_000719
Insert Size 7500 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. This clone may be unstable or toxic at high copy number in common E. coli strain. We recommend using a lower copy number E. coli strain, such as CopyCutter strain (http://www.epibio.com/item.asp?ID=435) for transformation and plasmid preparation. Please be aware that the DNA yield could be low. Additional aliquots of this clone can be ordered from OriGene.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_000719.4, NP_000710.4
RefSeq Size 8464 bp
RefSeq ORF 6417 bp
Locus ID 775
UniProt ID Q13936
Protein Families Druggable Genome, Ion Channels: Calcium, Transmembrane
Protein Pathways Alzheimer's disease, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Calcium signaling pathway, Cardiac muscle contraction, Dilated cardiomyopathy, GnRH signaling pathway, Hypertrophic cardiomyopathy (HCM), Long-term potentiation, MAPK signaling pathway, Type II diabetes mellitus, Vascular smooth muscle contraction
Gene Summary This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]
Transcript Variant: This variant (18), also referred to as HLCC70, lacks three alternate in-frame exons, compared to variant 1, resulting in a shorter protein (isoform 18), compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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