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15 Lipoxygenase 2 (ALOX15B) (NM_001039131) Human Untagged Clone
CAT＃: SC310837
ALOX15B (untagged)-Human arachidonate 15-lipoxygenase, type B (ALOX15B), transcript variant b
CNY 9,690.00
| Cited in 1 publication. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 15-LOX-2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC310837 representing NM_001039131.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCCGAGTTCAGGGTCAGGGTGTCCACCGGAGAAGCCTTCGGGGCTGGCACATGGGACAAAGTGTCT GTCAGCATCGTGGGGACCCGGGGAGAGAGCCCCCCACTGCCCCTGGACAATCTCGGCAAGGAGTTCACT GCGGGCGCTGAGGAGGACTTCCAGGTGACGCTCCCGGAGGACGTAGGCCGAGTGCTGCTGCTGCGCGTG CACAAGGCGCCCCCAGTGCTGCCCCTGCTGGGGCCCCTGGCCCCGGATGCCTGGTTCTGCCGCTGGTTC CAGCTGACACCGCCGCGGGGCGGCCACCTCCTCTTCCCCTGCTACCAGTGGCTGGAGGGGGCGGGGACC CTGGTGCTGCAGGAGGGTACAGCCAAGGTGTCCTGGGCAGACCACCACCCTGTGCTCCAGCAACAGCGC CAGGAGGAGCTTCAGGCCCGGCAGGAGATGTACCAGTGGAAGGCTTACAACCCAGGTTGGCCTCACTGC CTGGATGAAAAGACAGTGGAAGACTTGGAGCTCAATATCAAATACTCCACAGCCAAGAATGCCAACTTT TATCTACAGGCTGGCTCTGCTTTTGCAGAGATGAAAATCAAGGGGTTGCTGGACCGCAAGGGGCTCTGG AGGAGTCTGAATGAGATGAAAAGGATCTTCAACTTCCGGAGGACCCCAGCAGCTGAGCACGCATTTGAG CACTGGCAGGAGGACGCCTTCTTCGCCTCCCAGTTCCTGAATGGTCTCAACCCTGTCCTGATCCGCCGC TGTCACTACCTCCCAAAGAACTTCCCCGTCACTGATGCCATGGTGGCCTCAGTGTTGGGTCCTGGGACC AGCTTGCAGGCTGAGCTAGAGAAGGGCTCCCTGTTCTTGGTGGATCACGGCATCCTCTCTGGCATCCAG ACCAATGTCATTAATGGGAAGCCTCAGTTCTCTGCGGCCCCAATGACCCTGCTATACCAGAGCCCAGGC TGCGGGCCGCTGCTGCCTCTCGCCATCCAGCTCAGCCAGACCCCCGGCCCAAACAGCCCCATCTTCCTG CCCACTGATGACAAGTGGGACTGGTTGCTGGCCAAGACCTGGGTGCGCAATGCCGAGTTCTCCTTCCAT GAGGCCCTCACGCACCTGCTGCACTCACATCTGCTGCCTGAGGTCTTCACCCTGGCTACCCTGCGTCAG CTGCCCCACTGCCACCCTCTCTTCAAGTCCACAGGCATCGGCATTGAAGGCTTCTCTGAGTTGATACAG AGGAACATGAAGCAGCTGAACTATTCTCTCCTGTGTCTGCCTGAGGATATCCGGACCCGAGGAGTTGAA GACATCCCAGGCTACTACTACCGTGATGATGGGATGCAGATCTGGGGTATACCCTCCTCACTGGAGACC CGGGAAGCCCTGGTGCAGTATGTCACCATGGTGATATTCACCTGCTCCGCCAAGCATGCGGCTGTCAGT GCAGGGCAGTTTGACTCCTGTGCTTGGATGCCCAACCTGCCACCCAGCATGCAGCTGCCACCACCCACC TCCAAAGGCCTGGCAACATGCGAGGGCTTCATAGCCACCCTCCCACCTGTCAATGCCACATGTGATGTC ATCCTTGCTCTCTGGTTGCTGAGCAAGGAGCCTGGAGACCAAAGGCCCCTGGGCACCTATCCGGATGAG CACTTCACAGAGGAGGCCCCTCGGCGGAGCATCGCCACCTTCCAGAGCCGCCTGGCCCAGATCTCGAGG GGCATCCAGGAGCGGAACCAGGGCCTGGTGCTGCCCTACACCTACCTAGACCCTCCCCTCATCGAGAAC AGCGTCTCCATCTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001039131 |
| Insert Size | 1809 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001039131.1 |
| RefSeq Size | 2508 bp |
| RefSeq ORF | 1809 bp |
| Locus ID | 247 |
| UniProt ID | O15296 |
| Protein Families | Druggable Genome |
| Protein Pathways | Arachidonic acid metabolism, Metabolic pathways |
| MW | 67.3 kDa |
| Gene Summary | This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (b) has multiple differences in the coding region but maintains the reading frame, compared to variant d. The encoded isoform (b) is shorter than isoform d. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products
,null,
Nature chemical biology
,PubMed ID 32393899
[ALOX15B]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214075 | ALOX15B (Myc-DDK-tagged)-Human arachidonate 15-lipoxygenase, type B (ALOX15B), transcript variant b |
CNY 4,480.00 |
|
| RC214075L3 | Lenti-ORF clone of ALOX15B (Myc-DDK-tagged)-Human arachidonate 15-lipoxygenase, type B (ALOX15B), transcript variant b |
CNY 7,130.00 |
|
| RC214075L4 | Lenti-ORF clone of ALOX15B (mGFP-tagged)-Human arachidonate 15-lipoxygenase, type B (ALOX15B), transcript variant b |
CNY 7,130.00 |
|
| RG214075 | ALOX15B (tGFP-tagged) - Human arachidonate 15-lipoxygenase, type B (ALOX15B), transcript variant b |
CNY 5,700.00 |
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