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CCN1 (CYR61) (NM_001554) Human Untagged Clone
CAT＃: SC310465
CYR61 (untagged)-Human cysteine-rich, angiogenic inducer, 61 (CYR61)
CNY 3,656.00
CNY 7,220.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CYR61; GIG1; IGFBP10 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC310465 sequence for NM_001554 edited (data generated by NextGen Sequencing)
ATGAGCTCCCGCATCGCCAGGGCGCTCGCCTTAGTCGTCACCCTTCTCCACTTGACCAGG CTGGCGCTCTCCACCTGCCCCGCTGCCTGCCACTGCCCCCTGGAGGCGCCCAAGTGCGCG CCGGGAGTCGGGCTGGTCCGGGACGGCTGCGGCTGCTGTAAGGTCTGCGCCAAGCAGCTC AACGAGGACTGCAGCAAAACGCAGCCCTGCGACCACACCAAGGGGCTGGAATGCAACTTC GGCGCCAGCTCCACCGCTCTGAAGGGGATCTGCAGAGCTCAGTCAGAGGGCAGACCCTGT GAATATAACTCCAGAATCTACCAAAACGGGGAAAGTTTCCAGCCCAACTGTAAACATCAG TGCACATGTATTGATGGCGCCGTGGGCTGCATTCCTCTGTGTCCCCAAGAACTATCTCTC CCCAACTTGGGCTGTCCCAACCCTCGGCTGGTCAAAGTTACCGGGCAGTGCTGCGAGGAG TGGGTCTGTGACGAGGATAGTATCAAGGACCCCATGGAGGACCAGGACGGCCTCCTTGGC AAGGAGCTGGGATTCGATGCCTCCGAGGTGGAGTTGACGAGAAACAATGAATTGATTGCA GTTGGAAAAGGCAGCTCACTGAAGCGGCTCCCTGTTTTTGGAATGGAGCCTCGCATCCTA TACAACCCTTTACAAGGCCAGAAATGTATTGTTCAAACAACTTCATGGTCCCAGTGCTCA AAGACCTGTGGAACTGGTATCTCCACACGAGTTACCAATGACAACCCTGAGTGCCGCCTT GTGAAAGAAACCCGGATTTGTGAGGTGCGGCCTTGTGGACAGCCAGTGTACAGCAGCCTG AAAAAGGGCAAGAAATGCAGCAAGACCAAGAAATCCCCCGAACCAGTCAGGTTTACTTAC GCTGGATGTTTGAGTGTGAAGAAATACCGGCCCAAGTACTGCGGTTCCTGCGTGGACGGC CGATGCTGCACGCCCCAGCTGACCAGGACTGTGAAGATGCGGTTCCGCTGCGAAGATGGG GAGACATTTTCCAAGAACGTCATGATGATCCAGTCCTGCAAATGCAACTACAACTGCCCG CATGCCAATGAAGCAGCGTTTCCCTTCTACAGGCTGTTCAATGACATTCACAAATTTAGG GACTAA Clone variation with respect to NM_001554.4 >OriGene 5' read for NM_001554 unedited
NGGCGGTCAAAATTGTATACGACTCCTATAGGCGGCCCGCGAATCGGCACCAGGCGCCCC CGAGCAGCGCCCGCGCCCTCCGCGCCTTCTCCGCCGGGACCTCGAGCGAAAGACGCCCGC CCGCCGCCCAGCCCTCGCCTCCCTGCCCACCGGGCACACCGCGCCGCCACCCCGACCCCG CTGCGCACGGCCTGTCCGCTGCACACCAGCTTGTTGGCGTCTTCGTCGCCGCGCTCGCCC CGGGCTACTCCTGCGCGCCACAATGAGCTCCCGCATCGCCAGGGCGCTCGCCTTAGTCGT CACCCTTCTCCACTTGACCAGGCTGGCGCTCTCCACCTGCCCCGCTGCCTGCCACTGCCC CCTGGAGGCGCCCAAGTGCGCGCCGGGAGTCGGGCTGGTCCGGGACGGCTGCGGCTGCTG TAAGGTCTGCGCCAAGCAGCTCAACGAGGACTGCAGCAAAACGCAGCCCTGCGACCACAC CAAGGGGCTGGAATGCAACTTCGGCGCCAGCTCCACCGCTCTGAAGGGGATCTGCAGAGC TCAGTCAGAGGGCAGACCCTGTGAATATAACTCCAGAATCTACCAAAACGGGGAAAGTTT CCAGCCCAACTGTAAACATCAGTGCACATGTATTGATGGCGCCGTGGGCTGCATTCCTCT GTGTCCCCAAGAACTATCTCTCCCCAACTTGGGCTGTCCCAACCCTCGGCTGGTCAAAGT TACCGGGCAGTGCTGCGAGGAGTGGGTCTGTGACGAGGATAGTATCAAGGACCCCATGGN AGACCAGGACNGCCTCCTTGGCAGGAGCTGGGATTCGATGCCTCCGAGGTGGAGTTGACG AGAACAATGAATGATNGCAGTTGGAAAAGGCAGCTCACTGAAGCGGCTCCCTGGNTTTGG AATGGAGCTCGCATCTATACACC >OriGene 3' read for NM_001554 unedited
AGGNANAGCACTGGGGNAGGGTCACAGGCTGCCACCCGGGTATCTGTTGAGGCAAACAGC TATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTAGGTAAAT ATTTCTTTATTAAATGGTTAATTCCATAAATAAAATCTTTTCACTGAATATAAAATTAAA ATCATTTACAAATTATTCCAGTATTACATTTCCCCTCCCTCCCCAAAAGCTACATTTTGA TAAATAAAACATTCAGTCTTAAAACACCTGATTTCTGTTTGCAGTTTAGAGTGCAGATAG CTGCCTCTCACAGACACTCATGGAGTGTCCCCCTTCAGGAAGGGATGGAATGCCCTCCCA TTTACTTTTGTCAAAGGACAAATAAAAGCTTTAAACTGTCCAACTAATCTTATTATCTCT TTTACGACTGTAGAACCCCAAAAGGAAAAAAGCCTAGAGAAAATATGCTTAGCATATAAT TTACAAACAGAAAACAGAATGTCATCAACTCCACAAGCTCCAAAATGAAGCAGTAACATG TGCTCCAATACTATGAAGCAAAGTATTCTCCAATCGTGGCTGCATTAGTGTCCATCCGCA CCAGCACCCTTGGCAGTTTCGAAATACCTTAATGCTCCTCAAGAATGAGCAAGGCTTCCT TTCTACAATGAGTCCCATCACCCACACCACCCCCGCCCATTTTCTCCATGATTCTGATTC TGACACTCTNTCTCCTTGTTTGTCTAGGTGTGCCCTGGAAACCCAGTAGCATTTAGTCCC TAAATTTGTGAATGTCATTGCACAGCCTGTAGAAGGGAAACGCTGCTTATTGGCATGCGG GCATTTGTAGTTGCATTTGCAGGACTGGATCATCATGACGTTCTTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001554 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001554.3, NP_001545.2 |
| RefSeq Size | 2037 bp |
| RefSeq ORF | 1146 bp |
| Locus ID | 3491 |
| UniProt ID | O00622 |
| Domains | IB, tsp_1, VWC, CT, Cys_knot |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein |
| Gene Summary | The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation. [provided by RefSeq, Sep 2011] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Identifying CYR61 as a Potential Anti-fibrotic and Pro-angiogenic Mediator in Scleroderma
,Tsou, PS;Khanna, D;Sawalha, AH;,
Arthritis & rheumatology (Hoboken, N.J.) 2019
,PubMed ID 30884213
[CCN1]
|
|
Histone Deacetylase 5 Is Overexpressed in Scleroderma Endothelial Cells and Impairs Angiogenesis via Repression of Proangiogenic Factors
,Tsou, PS;Wren, JD;Amin, MA;Schiopu, E;Fox, DA;Khanna, D;Sawalha, AH;,
Arthritis & rheumatology
,PubMed ID 27482699
[CCN1]
|
|
Substance P-Mediated Expression of the Pro-Angiogenic Factor CCN1 Modulates the Course of Colitis
,Hon-Wai Koon, Dezheng Zhao, Hua Xu, Collin Bowe, Alan Moss, Mary P. Moyer, and Charalabos Pothoulakis,
Am. J. Pathol., Aug 2008; 173: 400 - 410.
[CCN1]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203492 | CYR61 (Myc-DDK-tagged)-Human cysteine-rich, angiogenic inducer, 61 (CYR61) |
CNY 5,488.00 |
|
| RC203492L1 | Lenti ORF clone of Human cysteine-rich, angiogenic inducer, 61 (CYR61), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC203492L2 | Lenti ORF clone of Human cysteine-rich, angiogenic inducer, 61 (CYR61), mGFP tagged |
CNY 5,890.00 |
|
| RC203492L3 | Lenti ORF clone of Human cysteine-rich, angiogenic inducer, 61 (CYR61), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203492L4 | Lenti ORF clone of Human cysteine-rich, angiogenic inducer, 61 (CYR61), mGFP tagged |
CNY 5,890.00 |
|
| RG203492 | CYR61 (tGFP-tagged) - Human cysteine-rich, angiogenic inducer, 61 (CYR61) |
CNY 7,088.00 |
