IDN3 (NIPBL) (NM_015384) Human Untagged Clone

CAT#: SC309870

NIPBL (untagged)-Human Nipped-B homolog (Drosophila) (NIPBL), transcript variant B



  "NM_015384" in other vectors (2)

CNY 52,060.00


货期*
13周

规格
    • 10 ug

Product images

经常一起买 (4)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


NIPBL rabbit polyclonal antibody
    • 25 ul

CNY 800.00
CNY 1,280.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms CDLS; CDLS1; IDN3; IDN3-B; Scc2
Vector pCMV6 series
Sequence Data
>NCBI ORF sequence for NM_015384, the custom clone sequence may differ by one or more nucleotides
ATGAATGGGGATATGCCCCATGTCCCCATTACTACTCTTGCGGGGATTGCTAGTCTCACA
GACCTCCTGAACCAGCTGCCTCTTCCATCTCCTTTACCTGCTACAACTACAAAGAGCCTT
CTCTTTAATGCACGAATAGCAGAAGAGGTGAACTGCCTTTTGGCTTGTAGGGATGACAAT
TTGGTTTCACAGCTTGTCCATAGCCTCAACCAGGTATCAACAGATCACATAGAGTTGAAA
GATAACCTTGGCAGTGATGACCCAGAAGGTGACATACCAGTCTTGTTGCAGGCCGTCCTG
GCAAGGAGTCCTAATGTTTTCAGGGAGAAAAGCATGCAGAACAGATATGTACAAAGTGGA
ATGATGATGTCTCAGTATAAACTTTCTCAGAATTCCATGCACAGTAGTCCTGCATCTTCC
AATTATCAACAAACCACTATCTCACATAGCCCCTCCAGCCGGTTTGTGCCACCACAGACA
AGCTCTGGGAACAGATTTATGCCACAGCAAAATAGCCCAGTGCCTAGTCCATACGCCCCA
CAAAGCCCTGCAGGATACATGCCATATTCCCATCCTTCAAGTTACACAACACATCCACAG
ATGCAACAAGCATCGGTATCAAGTCCCATTGTTGCAGGTGGTTTGAGAAACATACATGAT
AATAAAGTTTCTGGTCCGTTGTCTGGCAATTCAGCTAATCATCATGCTGATAATCCTAGA
CATGGTTCAAGTGAGGACTACCTACACATGGTGCACAGGCTAAGTAGTGACGATGGAGAT
TCTTCAACAATGAGGAATGCTGCATCTTTTCCCTTGAGATCTCCACAGCCAGTATGCTCC
CCTGCTGGAAGTGAAGGAACTCCTAAAGGCTCAAGACCACCTTTAATCCTACAATCTCAG
TCTCTACCTTGTTCATCACCTCGAGATGTTCCACCAGATATCTTGCTAGATTCTCCAGAA
AGAAAACAAAAGAAGCAGAAGAAAATGAAATTAGGCAAGGATGAAAAAGAGCAGAGTGAG
AAAGCGGCAATGTATGATATAATTAGTTCTCCATCCAAGGACTCTACTAAACTTACATTA
AGACTTTCTCGTGTAAGGTCTTCAGACATGGACCAGCAAGAGGATATGATTTCTGGTGTG
GAAAATAGCAATGTTTCAGAAAATGATATTCCTTTTAATGTGCAGTACCCAGGACAGACT
TCAAAAACACCCATTACTCCACAAGATATAAACCGCCCACTAAATGCTGCTCAATGTTTG
TCGCAGCAAGAACAAACAGCATTCCTTCCAGCAAATCAAGTGCCTGTTTTACAACAGAAC
ACTTCAGTTGCTGCAAAACAACCCCAGACTTCTGTGGTACAGAATCAACAACAGATATCA
CAACAGGGACCTATATATGATGAAGTGGAATTGGATGCATTGGCTGAAATTGAGCGAATA
GAGAGAGAATCAGCTATTGAAAGGGAGCGCTTCTCAAAAGAAGTTCAAGATAAAGATAAG
CCTTTGAAAAAAAGAAAACAAGATTCTTACCCACAGGAGGCTGGGGGTGCTACAGGAGGT
AATAGACCAGCTTCTCAGGAGACGGGTTCTACGGGAAATGGGTCAAGGCCAGCATTAATG
GTTAGCATTGATCTTCATCAGGCAGGAAGAGTGGACTCTCAGGCTTCTATAACTCAGGAT
TCAGACTCCATAAAAAAGCCTGAAGAAATCAAACAATGTAATGATGCACCTGTTTCTGTT
CTTCAGGAAGATATTGTTGGAAGTCTTAAATCTACACCAGAAAACCATCCTGAGACACCT
AAAAAAAAGTCTGATCCTGAGCTTTCAAAGAGTGAAATGAAACAAAGTGAAAGTAGATTA
GCAGAATCTAAACCAAATGAAAACCGATTGGTGGAGACAAAATCAAGTGAAAATAAGTTA
GAAACTAAAGTTGAGACCCAAACAGAAGAACTTAAACAGAATGAGAGCAGAACAACTGAA
TGCAAACAAAACGAGAGCACCATAGTTGAGCCTAAACAAAATGAAAATAGACTGTCTGAC
ACAAAACCAAATGACAACAAACAAAATAATGGCAGATCAGAAACAACAAAATCAAGGCCT
GAAACCCCAAAGCAAAAGGGTGAAAGCCGGCCTGAGACTCCAAAACAAAAGAGTGATGGG
CATCCTGAAACCCCAAAACAGAAGGGTGATGGAAGGCCTGAAACTCCAAAGCAAAAAGGT
GAGAGCCGCCCTGAAACTCCAAAGCAAAAAAATGAAGGGCGACCTGAAACACCAAAACAC
AGGCATGACAATAGGAGGGATTCTGGAAAGCCATCTACAGAGAAAAAACCTGAAGTGTCT
AAACATAAACAAGATACTAAATCTGACTCACCTCGGTTAAAATCAGAACGAGCTGAAGCC
TTAAAGCAGAGACCTGATGGGCGATCTGTTTCTGAGTCACTAAGACGTGACCATGATAAT
AAACAAAAATCAGATGACAGGGGTGAATCAGAGCGACATCGAGGGGATCAGTCTAGGGTT
CGAAGACCAGAAACATTGAGATCCTCTAGTAGAAATGAACATGGCATTAAATCTGATAGT
TCAAAAACTGATAAACTAGAACGAAAACACAGGCATGAATCAGGGGACTCAAGGGAAAGA
CCATCTTCTGGGGAACAAAAATCAAGACCTGACAGTCCTCGTGTTAAACAAGGAGATTCT
AATAAATCAAGATCTGATAAACTTGGTTTTAAATCACCAACTAGTAAAGATGACAAAAGG
ACAGAGGGTAACAAGAGTAAAGTAGACACTAATAAAGCACACCCTGACAATAAGGCAGAA
TTTCCAAGTTATTTGTTGGGGGGCAGGTCTGGTGCGTTGAAAAATTTTGTCATTCCGAAA
ATCAAGAGGGATAAAGATGGCAATGTTACTCAGGAGACAAAGAAAATGGAAATGAAAGGA
GAGCCGAAAGACAAAGTAGAAAAAATAGGATTAGTTGAAGATCTAAATAAAGGAGCTAAG
CCTGTAGTTGTGCTACAAAAACTGTCTTTGGATGATGTTCAGAAACTTATTAAAGATAGA
GAGGACAAATCAAGAAGTTCCCTTAAACCTATCAAGAATAAACCATCAAAGTCAAATAAA
GGTAGTATAGATCAATCAGTGTTAAAAGAATTACCCCCTGAACTCCTGGCAGAAATTGAG
TCCACCATGCCACTTTGTGAACGTGTGAAAATGAACAAACGCAAGCGTAGCACAGTTAAT
GAAAAGCCAAAATATGCTGAAATCAGTTCAGATGAAGATAATGATAGTGATGAAGCTTTT
GAATCCTCTAGGAAACGACATAAAAAAGATGATGATAAAGCTTGGGAATATGAAGAGCGT
GACAGAAGAAGCTCTGGGGATCATAGGAGAAGTGGCCACTCTCATGAAGGAAGAAGGAGT
TCAGGTGGTGGTCGTTATCGAAACCGAAGTCCGTCAGATTCTGACATGGAAGATTATTCT
CCTCCTCCCAGCCTTAGTGAGGTTGCTAGGAAAATGAAGAAAAAAGAAAAACAGAAGAAA
AGGAAAGCATATGAACCAAAACTAACACCTGAAGAAATGATGGACTCTTCAACTTTTAAG
AGATTCACAGCCTCAATAGAGAATATTTTGGATAATTTGGAAGATATGGATTTTACTGCG
TTTGGTGATGATGATGAAATTCCTCAGGAACTGCTCTTAGGAAAACATCAGCTTAATGAA
CTTGGCAGTGAATCTGCTAAAATAAAAGCAATGGGTATAATGGATAAGCTTTCAACTGAC
AAAACTGTGAAAGTCTTAAATATCTTGGAGAAGAATATTCAGGATGGGTCAAAGCTTTCC
ACTTTGTTAAATCATAATAACGATACTGAAGAAGAAGAAAGGTTATGGAGAGACCTTATT
ATGGAGAGAGTTACAAAATCAGCGGATGCTTGTCTTACAACTATCAACATTATGACATCC
CCTAACATGCCAAAAGCTGTGTACATTGAGGATGTAATTGAAAGAGTTATACAGTACACT
AAATTTCATTTGCAGAATACACTTTATCCTCAGTATGATCCTGTTTACAGATTAGATCCT
CATGGAGGAGGCTTATTAAGTTCAAAAGCAAAACGGGCTAAATGTTCTACCCATAAGCAG
AGAGTAATAGTAATGCTTTATAACAAAGTTTGTGACATTGTTAGCAGCTTATCAGAATTG
CTAGAGATACAACTTCTTACAGACACAACAATTCTTCAGGTTTCATCTATGGGAATAACA
CCATTTTTTGTGGAAAATGTCAGTGAACTACAGTTGTGTGCCATTAAGTTAGTCACTGCA
GTATTCTCAAGATATGAAAAACATAGGCAGTTAATTTTGGAAGAAATTTTTACTTCACTT
GCAAGATTACCAACCAGCAAGAGGAGTTTAAGGAACTTCAGGTTAAACAGTAGTGATATG
GATGGAGAACCTATGTATATTCAGATGGTTACAGCACTGGTTTTACAACTTATTCAGTGT
GTGGTACACTTACCATCATCAGAGAAGGACTCTAATGCAGAAGAAGATTCAAATAAAAAA
ATTGACCAGGATGTTGTCATTACTAACTCTTATGAAACAGCTATGCGAACAGCCCAAAAC
TTCCTCTCCATCTTCCTTAAAAAATGTGGTAGTAAGCAAGGTGAAGAAGATTACAGACCA
CTGTTTGAAAATTTTGTTCAAGACCTTCTTTCAACAGTCAATAAGCCTGAATGGCCAGCT
GCTGAACTACTCCTTAGTTTGTTAGGGAGACTGTTGGTTCATCAGTTCAGTAACAAGTCA
ACAGAGATGGCTTTAAGAGTGGCATCTCTTGATTACCTTGGAACTGTTGCTGCACGGCTA
AGAAAAGATGCTGTTACAAGCAAAATGGATCAAGGATCTATAGAACGCATTTTAAAACAG
GTTTCAGGAGGGGAAGATGAAATCCAACAATTACAAAAAGCATTGCTTGATTACTTGGAT
GAAAACACTGAGACTGATCCTTCACTAGTGTTTTCTCGTAAATTCTATATAGCCCAGTGG
TTTCGAGACACAACTCTGGAAACAGAAAAAGCAATGAAATCACAAAAAGATGAAGAATCA
TCTGAAGGAACACATCATGCAAAGGAAATTGAGACAACTGGCCAAATTATGCATCGAGCT
GAAAACCGAAAAAAGTTTCTTAGAAGCATTATCAAAACCACACCTTCTCAGTTTAGCACA
TTAAAGATGAACTCTGATACTGTGGACTATGATGATGCTTGCTTGATTGTTCGATACTTG
GCCTCCATGAGGCCGTTTGCCCAGAGCTTTGATATTTATTTGACACAGATCCTACGAGTT
CTTGGTGAAAATGCAATTGCTGTTCGAACAAAAGCCATGAAGTGTTTGTCTGAGGTTGTT
GCTGTAGACCCCAGTATTCTAGCAAGGCTTGATATGCAACGAGGTGTTCATGGACGATTG
ATGGATAATTCGACTAGTGTCCGAGAAGCAGCAGTAGAATTACTAGGTCGATTTGTCCTT
TGTCGACCTCAGCTTGCTGAACAGTATTATGATATGCTGATTGAAAGAATATTGGATACT
GGTATCAGTGTCAGGAAAAGAGTAATAAAGATTCTCAGAGACATTTGTATTGAACAACCA
ACATTTCCAAAAATCACAGAAATGTGTGTAAAAATGATTCGCAGAGTCAATGATGAAGAG
GGCATTAAGAAATTAGTAAATGAAACATTCCAGAAACTCTGGTTTACTCCAACTCCACAC
AATGACAAAGAAGCAATGACAAGGAAAATTTTAAACATTACCGATGTGGTTGCAGCATGC
AGAGATACTGGATATGACTGGTTTGAGCAACTGCTTCAAAACTTGTTGAAGTCCGAAGAG
GATTCCTCATATAAACCTGTGAAGAAAGCTTGTACTCAACTTGTTGATAACCTAGTTGAG
CACATTCTTAAATATGAGGAATCTCTAGCTGACTCTGACAATAAAGGTGTGAATTCTGGA
AGATTGGTAGCTTGCATAACCACTTTGTTCTTATTCAGCAAAATAAGACCCCAGCTCATG
GTTAAACATGCAATGACTATGCAACCATACCTTACCACTAAATGTAGTACGCAAAATGAT
TTCATGGTTATCTGCAATGTTGCAAAAATCCTAGAGCTAGTTGTACCACTGATGGAGCAT
CCAAGTGAAACTTTTCTTGCCACTATTGAGGAAGATCTAATGAAGCTCATCATCAAATAT
GGCATGACTGTAGTGCAACATTGTGTGAGCTGTCTTGGAGCTGTTGTAAATAAAGTGACA
CAAAATTTTAAATTTGTGTGGGCTTGTTTCAATAGATACTATGGTGCCATTTCAAAATTA
AAAAGTCAACACCAAGAGGACCCAAATAACACTTCACTTCTAACAAACAAACCAGCACTT
CTTAGATCCCTTTTCACCGTTGGAGCACTATGTCGGCATTTTGATTTTGATCTGGAAGAT
TTTAAAGGCAACAGCAAGGTTAACATAAAAGATAAAGTACTTGAACTATTGATGTATTTT
ACAAAACACTCAGATGAAGAAGTACAAACAAAAGCTATCATTGGTCTAGGATTTGCCTTT
ATTCAGCATCCAAGTCTAATGTTCGAGCAAGAAGTGAAGAATCTATATAATAATATTTTA
TCTGATAAGAACTCCTCAGTCAATTTAAAAATACAAGTGTTAAAAAACCTCCAGACCTAC
CTACAAGAAGAAGATACACGTATGCAGCAGGCAGATAGAGACTGGAAGAAAGTTGCAAAA
CAGGAAGACTTAAAAGAAATGGGTGATGTTTCCTCAGGGATGAGTAGTTCCATCATGCAG
CTTTATCTCAAACAGGTGCTTGAGGCATTTTTTCACACCCAGTCAAGTGTACGCCACTTT
GCCCTAAATGTCATTGCATTGACTCTAAATCAAGGTCTTATTCATCCAGTTCAGTGTGTG
CCATATTTAATTGCTATGGGCACAGACCCAGAACCTGCTATGCGGAACAAGGCTGATCAG
CAACTTGTGGAAATAGACAAAAAATATGCTGGATTCATTCATATGAAAGCAGTGGCTGGT
ATGAAGATGTCTTACCAGGTACAACAGGCAATCAACACATGCCTAAAAGATCCTGTAAGG
GGTTTCAGACAAGACGAGTCCTCTAGCGCTTTGTGTTCACACCTTTACTCCATGATCCGT
GGAAACCGCCAACACAGACGAGCCTTTCTTATTTCTTTACTCAACCTCTTTGATGACACA
GCAAAAACAGACGTGACTATGCTCTTGTATATAGCAGACAATCTAGCCTGTTTTCCATAC
CAGACACAGGAAGAGCCGTTGTTTATAATGCATCATATAGACATTACACTCTCAGTTTCT
GGTAGTAACCTACTGCAGTCATTCAAGGAGTCTATGGTAAAGGACAAAAGGAAAGAGAGA
AAATCATCACCTAGTAAGGAAAATGAGTCAAGCGACAGTGAAGAAGAAGTTTCCAGGCCT
CGGAAGTCACGGAAACGTGTAGATTCAGATTCAGATTCAGATTCAGAAGACGATATAAAT
TCAGTGATGAAATGTTTGCCAGAAAATTCAGCTCCTTTAATCGAATTTGCAAATGTGTCC
CAGGGTATTTTATTACTTCTCATGTTAAAACAACATTTGAAGAATCTTTGTGGATTTTCT
GATAGTAAAATTCAGAAGTACTCTCCATCTGAATCTGCAAAAGTATATGATAAAGCGATA
AACCGAAAAACAGGAGTTCATTTTCATCCAAAACAAACACTGGACTTCCTGCGGAGTGAC
ATGGCTAATTCCAAAATCACAGAAGAGGTGAAAAGGAGTATAGTAAAACAGTATCTAGAT
TTCAAACTTCTCATGGAACATCTGGACCCTGATGAAGAAGAAGAAGAAGGGGAGGTTTCA
GCTAGCACAAATGCTCGGAACAAAGCAATTACCTCACTGCTTGGAGGAGGCAGCCCTAAA
AATAATACAGCAGCAGAGACAGAAGATGATGAAAGTGATGGGGAGGATAGAGGAGGAGGC
ACTTCAGGGGTGAGGCGGAGGAGGAGTCAACGTATTTCGCAGCGTATTACGTAA
Restriction Sites Please inquire     
ACCN NM_015384
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_015384.3, NP_056199.2
RefSeq Size 8648 bp
RefSeq ORF 8094 bp
Locus ID 25836
UniProt ID Q6KC79
Gene Summary This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and cognitive disability. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (B) is alternatively spliced at the 3' end compared to transcript variant A. It encodes an isoform (B) with a shorter, distinct C-terminus, compared to isoform A.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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