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PPAR alpha (PPARA) (NM_005036) Human Untagged Clone
CAT＃: SC308984
PPARA (untagged)-Human peroxisome proliferator-activated receptor alpha (PPARA), transcript variant 5
CNY 3,656.00
CNY 7,410.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | hPPAR; NR1C1; PPAR; PPAR-alpha; PPARalpha |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_005036 edited
ATGGTGGACACGGAAAGCCCACTCTGCCCCCTCTCCCCACTCGAGGCCGGCGATCTAGAG AGCCCGTTATCTGAAGAGTTCCTGCAAGAAATGGGAAACATCCAAGAGATTTCGCAATCC ATCGGCGAGGATAGTTCTGGAAGCTTTGGCTTTACGGAATACCAGTATTTAGGAAGCTGT CCTGGCTCAGATGGCTCGGTCATCACGGACACGCTTTCACCAGCTTCGAGCCCCTCCTCG GTGACTTATCCTGTGGTCCCCGGCAGCGTGGACGAGTCTCCCAGTGGAGCATTGAACATC GAATGTAGAATCTGCGGGGACAAGGCCTCAGGCTATCATTACGGAGTCCACGCGTGTGAA GGCTGCAAGGGCTTCTTTCGGCGAACGATTCGACTCAAGCTGGTGTATGACAAGTGCGAC CGCAGCTGCAAGATCCAGAAAAAGAACAGAAACAAATGCCAGTATTGTCGATTTCACAAG TGCCTTTCTGTCGGGATGTCACACAACGCGATTCGTTTTGGACGAATGCCAAGATCTGAG AAAGCAAAACTGAAAGCAGAAATTCTTACCTGTGAACATGACATAGAAGATTCTGAAACT GCAGATCTCAAATCTCTGGCCAAGAGAATCTACGAGGCCTACTTGAAGAACTTCAACATG AACAAGGTCAAAGCCCGGGTCATCCTCTCAGGAAAGGCCAGTAACAATCCACCTTTTGTC ATACATGATATGGAGACACTGTGTATGGCTGAGAAGACGCTGGTGGCCAAGCTGGTGGCC AATGGCATCCAGAACAAGGAGGCGGAGGTCCGCATCTTTCACTGCTGCCAGTGCACGTCA GTGGAGACCGTCACGGAGCTCACGGAATTCGCCAAGGCCATCCCAGGCTTCGCAAACTTG GACCTGAACGATCAAGTGACATTGCTAAAATACGGAGTTTATGAGGCCATATTCGCCATG CTGTCTTCTGTGATGAACAAAGACGGGATGCTGGTAGCGTATGGAAATGGGTTTATAACT CGTGAATTCCTAAAAAGCCTAAGGAAACCGTTCTGTGATATCATGGAACCCAAGTTTGAT TTTGCCATGAAGTTCAATGCACTGGAACTGGATGACAGTGATATCTCCCTTTTTGTGGCT GCTATCATTTGCTGTGGAGATCGTCCTGGCCTTCTAAACGTAGGACACATTGAAAAAATG CAGGAGGGTATTGTACATGTGCTCAGACTCCACCTGCAGAGCAACCACCCGGACGATATC TTTCTCTTCCCAAAACTTCTTCAAAAAATGGCAGACCTCCGGCAGCTGGTGACGGAGCAT GCGCAGCTGGTGCAGATCATCAAGAAGACGGAGTCGGATGCTGCGCTGCACCCGCTACTG CAGGAGATCTACAGGGACATGTACTGA >OriGene 5' read for NM_005036 unedited
NCCCGTTCAAATTTTGTATACGACTCACTAAAGGCGGCCGCGAATATCGCACGAAGAGCA GATTCAGTGTCATGTGAAGACGTGCTTCCTTGCTTCATAGATAAGAGTGCCACACCCCCC TGTCCCAGTGCACTGGGGCTGTGGATCCCTTCAAAGCTGAGATTGCCTGTCTGTGGTCTC CAGCGTTAAGCACAGTCATTAGCTCAGCTTGGAGCTCGGCGGCACAACCAGCACCATCTG GTCGCGATGGTGGACACGGAAAGCCCACTTCTTGCCCCCTCTCCCCACTCGAGGCCGGCG ATCTAGAGAGCCCGTTATCTGAAGAGTTCCTGCAAGAAATGGGAAACATCCAAGAGATTT CGCAATCCATCGGCAAGGATAGTTCTGGAAGCTTTGGCTTTACGGAATACCAGTATTTAG GAAAGCTGTCCTGGTNCAGATGGGCTCGGTCATCACGGACACGCTTTCACCAGCTTCGAG CCCTCCCTCGGTGACTATNCTTGTGGTCCCCGGCAGCGTGGACGAGTCTCCCAGTGGAGC ATTGAACATCGAATGTAGAATCTGCGGGGACAAGGCCTCAGGCTATCATTAACGGAGTCC ACGCGTGGTGAAGGCTGCAAGGGCCTTCTTTCGGCGAACGATTCGACTCAGCCTGGNNGT ATGAACAAGTGCGACCGCAGCTGGCNAGATCCAGAAAAAGAACAGAACANATGCCAATTA TGGGGNCGATTTCACAGTGCCTTTTTTGGGGGGGGGGATGTCACACACCCAAATTTTTTT TTTGGAACGATGCCCCAAAATTTTGAGAAAGCCAAACTGAAAGCAGAAATTCTTTACCTG TGACATGAATATTNAAAGATTCTGGACCTTGCAGATCTAAAAATCTCTGCCA >OriGene 3' read for NM_005036 unedited
ATGGGGTAATTCGTTAAGTACACCGATCNAGNGAANNNGAAGCNANGCGGAAGCANGGNG ATATAAGATGATGAAAAAAAAACTCTGGTAAAGCAATATACGAATAAGTCTGATATAAGT GGGACTACTGAGTGTGCCACCGGAGAACTATTTTATAATTTTGTGACAGACAGGGTATTG CTAGCCGCCTATGATGATTTGAAGGATGGGCTAAGTGATGGGGCCATCTTGGCCTCCAAA AGTGCTGGGATTACATGTGTGAGCCAGTGTGCCTAGGCTGATTACAAAAACCAAAACGGA ATAAATTTGTAATTTTTAAAAAAGGATGTTCTAACCATAAGTTTCACTTTTTTCTAGTGG AAGTTTNACACTGTGTCCTTACAACTCTAATATTTTTATAATGCTGGTCATGGGACCGTT ATAAATCCTAAAGATTGTTAAAATAATAATGACGTGAGAAGAGACAAATTTTATAAAGAT GAGGGGAGAGGAATTAAAGATACTTTGAGGTGCAGAGAGATTCCCTGGAGGAGGAGGTCC GGGGAGTTCCAGAGCAGGATCTAAAAAGGTTTAAGAGGAAAGTTTATATACACAGAGGAC CAAGAGAGAAAGTGGTATAAGGTGAATAGTTTTCTTGACAAAATAGGATAATAAAGGGTG ACTTCCCAACTGGGACAGAAGGGGGTAAGTTGGGTTTGAAGGCTAAAAAAAAAGTTCACA TTTTGTAAAAACTCGCTCACCACCAAGGAGACTAAAAAACCTAAACCACTGAAAAAAAAA CCCAAACTCGGGAAATGTGAAATATAAAGAAAACAGCCCAGTGAGGAAAATCGGCCCCCC TCCCCCGCCCCCCGCCCCACGCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005036 |
| Insert Size | 1407 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005036.4, NP_005027.2 |
| RefSeq Size | 10049 bp |
| RefSeq ORF | 1407 bp |
| Locus ID | 5465 |
| UniProt ID | Q07869 |
| Domains | HOLI, zf-C4 |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
| Protein Pathways | Adipocytokine signaling pathway, PPAR signaling pathway |
| Gene Summary | Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (5) represents the longer transcript. Variants 3 and 5 encode the same protein. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Human Receptor Activation By Aroclor 1260, a Polychlorinated Biphenyl Mixture
,Wahlang, B;Falkner, KC;Clair, HB;Al-Eryani, L;Prough, RA;States, JC;Coslo, DM;Omiecinski, CJ;Cave, MC;,
Toxicol. Sci.
,PubMed ID 24812009
[PPARA]
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Thyroid Hormone Regulates Hepatic Expression of Fibroblast Growth Factor 21 in a PPAR{alpha}-dependent Manner
,Andrew C. Adams, Inna Astapova, ffolliott M. Fisher, Michael K. Badman, Katherine E. Kurgansky, Jeffrey S. Flier, Anthony N. Hollenberg, and Eleftheria Maratos-Flier,
J. Biol. Chem., May 2010; 285: 14078 - 14082
[PPARA]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216176 | PPARA (Myc-DDK-tagged)-Human peroxisome proliferator-activated receptor alpha (PPARA), transcript variant 5 |
CNY 3,656.00 |
|
| RC216176L1 | Lenti ORF clone of Human peroxisome proliferator-activated receptor alpha (PPARA), transcript variant 5, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC216176L2 | Lenti ORF clone of Human peroxisome proliferator-activated receptor alpha (PPARA), transcript variant 5, mGFP tagged |
CNY 5,890.00 |
|
| RC216176L3 | Lenti ORF clone of Human peroxisome proliferator-activated receptor alpha (PPARA), transcript variant 5, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC216176L4 | Lenti ORF clone of Human peroxisome proliferator-activated receptor alpha (PPARA), transcript variant 5, mGFP tagged |
CNY 6,056.00 |
|
| RG216176 | PPARA (tGFP-tagged) - Human peroxisome proliferator-activated receptor alpha (PPARA), transcript variant 5 |
CNY 5,256.00 |
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