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MRP5 (ABCC5) (NM_005688) Human Untagged Clone
CAT＃: SC308972
ABCC5 (untagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1
CNY 14,760.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ABC33; EST277145; MOAT-C; MOATC; MRP5; pABC11; SMRP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_005688 edited
ATGAAGGATATCGACATAGGAAAAGAGTATATCATCCCCAGTCCTGGGTATAGAAGTGTG AGGGAGAGAACCAGCACTTCTGGGACGCACAGAGACCGTGAAGATTCCAAGTTCAGGAGA ACTCGACCGTTGGAATGCCAAGATGCCTTGGAAACAGCAGCCCGAGCCGAGGGCCTCTCT CTTGATGCCTCCATGCATTCTCAGCTCAGAATCCTGGATGAGGAGCATCCCAAGGGAAAG TACCATCATGGCTTGAGTGCTCTGAAGCCCATCCGGACTACTTCCAAACACCAGCACCCA GTGGACAATGCTGGGCTTTTTTCCTGTATGACTTTTTCGTGGCTTTCTTCTCTGGCCCGT GTGGCCCACAAGAAGGGGGAGCTCTCAATGGAAGACGTGTGGTCTCTGTCCAAGCACGAG TCTTCTGACGTGAACTGCAGAAGACTAGAGAGACTGTGGCAAGAAGAGCTGAATGAAGTT GGGCCAGACGCTGCTTCCCTGCGAAGGGTTGTGTGGATCTTCTGCCGCACCAGGCTCATC CTGTCCATCGTGTGCCTGATGATCACGCAGCTGGCTGGCTTCAGTGGACCAGCCTTCATG GTGAAACACCTCTTGGAGTATACCCAGGCAACAGAGTCTAACCTGCAGTACAGCTTGTTG TTAGTGCTGGGCCTCCTCCTGACGGAAATCGTGCGGTCTTGGTCGCTTGCACTGACTTGG GCATTGAATTACCGAACCGGTGTCCGCTTGCGGGGGGCCATCCTAACCATGGCATTTAAG AAGATCCTTAAGTTAAAGAACATTAAAGAGAAATCCCTGGGTGAGCTCATCAACATTTGC TCCAACGATGGGCAGAGAATGTTTGAGGCAGCAGCCGTTGGCAGCCTGCTGGCTGGAGGA CCCGTTGTTGCCATCTTAGGCATGATTTATAATGTAATTATTCTGGGACCAACAGGCTTC CTGGGATCAGCTGTTTTTATCCTCTTTTACCCAGCAATGATGTTTGCATCACGGCTCACA GCATATTTCAGGAGAAAATGCGTGGCCGCCACGGATGAACGTGTCCAGAAGATGAATGAA GTTCTTACTTACATTAAATTTATCAAAATGTATGCCTGGGTCAAAGCATTTTCTCAGAGT GTTCAAAAAATCCGCGAGGAGGAGCGTCGGATATTGGAAAAAGCCGGGTACTTCCAGAGC ATCACTGTGGGTGTGGCTCCCATTGTGGTGGTGATTGCCAGCGTGGTGACCTTCTCTGTT CATATGACCCTGGGCTTCGATCTGACAGCAGCACAGGCTTTCACAGTGGTGACAGTCTTC AATTCCATGACTTTTGCTTTGAAAGTAACACCGTTTTCAGTAAAGTCCCTCTCAGAAGCC TCAGTGGCTGTTGACAGATTTAAGAGTTTGTTTCTAATGGAAGAGGTTCACATGATAAAG AACAAACCAGCCAGTCCTCACATCAAGATAGAGATGAAAAATGCCACCTTGGCATGGGAC TCCTCCCACTCCAGTATCCAGAACTCGCCCAAGCTGACCCCCAAAATGAAAAAAGACAAG AGGGCTTCCAGGGGCAAGAAAGAGAAGGTGAGGCAGCTGCAGCGCACTGAGCATCAGGCG GTGCTGGCAGAGCAGAAAGGCCACCTCCTCCTGGACAGTGACGAGCGGCCCAGTCCCGAA GAGGAAGAAGGCAAGCACATCCACCTGGGCCACCTGCGCTTACAGAGGACACTGCACAGC ATCGATCTGGAGATCCAAGAGGGTAAACTGGTTGGAATCTGCGGCAGTGTGGGAAGTGGA AAAACCTCTCTCATTTCAGCCATTTTAGGCCAGATGACGCTTCTAGAGGGCAGCATTGCA ATCAGTGGAACCTTCGCTTATGTGGCCCAGCAGGCCTGGATCCTCAATGCTACTCTGAGA GACAACATCCTGTTTGGGAAGGAATATGATGAAGAAAGATACAACTCTGTGCTGAACAGC TGCTGCCTGAGGCCTGACCTGGCCATTCTTCCCAGCAGCGACCTGACGGAGATTGGAGAG CGAGGAGCCAACCTGAGCGGTGGGCAGCGCCAGAGGATCAGCCTTGCCCGGGCCTTGTAT AGTGACAGGAGCATCTACATCCTGGACGACCCCCTCAGTGCCTTAGATGCCCATGTGGGC AACCACATCTTCAATAGTGCTATCCGGAAACATCTCAAGTCCAAGACAGTTCTGTTTGTT ACCCACCAGTTACAGTACCTGGTTGACTGTGATGAAGTGATCTTCATGAAAGAGGGCTGT ATTACGGAAAGAGGCACCCATGAGGAACTGATGAATTTAAATGGTGACTATGCTACCATT TTTAATAACCTGTTGCTGGGAGAGACACCGCCAGTTGAGATCAATTCAAAAAAGGAAACC AGTGGTTCACAGAAGAAGTCACAAGACAAGGGTCCTAAAACAGGATCAGTAAAGAAGGAA AAAGCAGTAAAGCCAGAGGAAGGGCAGCTTGTGCAGCTGGAAGAGAAAGGGCAGGGTTCA GTGCCCTGGTCAGTATATGGTGTCTACATCCAGGCTGCTGGGGGCCCCTTGGCATTCCTG GTTATTATGGCCCTTTTCATGCTGAATGTAGGCAGCACCGCCTTCAGCACCTGGTGGTTG AGTTACTGGATCAAGCAAGGAAGCGGGAACACCACTGTGACTCGAGGGAACGAGACCTCG GTGAGTGACAGCATGAAGGACAATCCTCATATGCAGTACTATGCCAGCATCTACGCCCTC TCCATGGCAGTCATGCTGATCCTGAAAGCCATTCGAGGAGTTGTCTTTGTCAAGGGCACG CTGCGAGCTTCCTCCCGGCTGCATGACGAGCTTTTCCGAAGGATCCTTCGAAGCCCTATG AAGTTTTTTGACACGACCCCCACAGGGAGGATTCTCAACAGGTTTTCCAAAGACATGGAT GAAGTTGACGTGCGGCTGCCGTTCCAGGCCGAGATGTTCATCCAGAACGTTATCCTGGTG TTCTTCTGTGTGGGAATGATCGCAGGAGTCTTCCCGTGGTTCCTTGTGGCAGTGGGGCCC CTTGTCATCCTCTTTTCAGTCCTGCACATTGTCTCCAGGGTCCTGATTCGGGAGCTGAAG CGTCTGGACAATATCACGCAGTCACCTTTCCTCTCCCACATCACGTCCAGCATACAGGGC CTTGCCACCATCCACGCCTACAATAAAGGGCAGGAGTTTCTGCACAGATACCAGGAGCTG CTGGATGACAACCAAGCTCCTTTTTTTTTGTTTACGTGTGCGATGCGGTGGCTGGCTGTG CGGCTGGACCTCATCAGCATCGCCCTCATCACCACCACGGGGCTGATGATCGTTCTTATG CACGGGCAGATTCCCCCAGCCTATGCGGGTCTCGCCATCTCTTATGCTGTCCAGTTAACG GGGCTGTTCCAGTTTACGGTCAGACTGGCATCTGAGACAGAAGCTCGATTCACCTCGGTG GAGAGGATCAATCACTACATTAAGACTCTGTCCTTGGAAGCACCTGCCAGAATTAAGAAC AAGGCTCCCTCCCCTGACTGGCCCCAGGAGGGAGAGGTGACCTTTGAGAACGCAGAGATG AGGTACCGAGAAAACCTCCCTCTTGTCCTAAAGAAAGTATCCTTCACGATCAAACCTAAA GAGAAGATTGGCATTGTGGGGCGGACAGGATCAGGGAAGTCCTCGCTGGGGATGGCCCTC TTCCGTCTGGTGGAGTTATCTGGAGGCTGCATCAAGATTGATGGAGTGAGAATCAGTGAT ATTGGCCTTGCCGACCTCCGAAGCAAACTCTCTATCATTCCTCAAGAGCCGGTGCTGTTC AGTGGCACTGTCAGATCAAATTTGGACCCCTTCAACCAGTACACTGAAGACCAGATTTGG GATGCCCTGGAGAGGACACACATGAAAGAATGTATTGCTCAGCTACCTCTGAAACTTGAA TCTGAAGTGATGGAGAATGGGGATAACTTCTCAGTGGGGGAACGGCAGCTCTTGTGCATA GCTAGAGCCCTGCTCCGCCACTGTAAGATTCTGATTTTAGATGAAGCCACAGCTGCCATG GACACAGAGACAGACTTATTGATTCAAGAGACCATCCGAGAAGCATTTGCAGACTGTACC ATGCTGACCATTGCCCATCGCCTGCACACGGTTCTAGGCTCCGATAGGATTATGGTGCTG GCCCAGGGACAGGTGGTGGAGTTTGACACCCCATCGGTCCTTCTGTCCAACGACAGTTCC CGATTCTATGCCATGTTTGCTGCTGCAGAGAACAAGGTCGCTGTCAAGGGCTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_005688 |
| Insert Size | 4300 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005688.2, NP_005679.2 |
| RefSeq Size | 5851 bp |
| RefSeq ORF | 4314 bp |
| Locus ID | 10057 |
| UniProt ID | O15440 |
| Domains | ABC_membrane, ABC_tran, AAA |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | ABC transporters |
| Gene Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224017 | ABCC5 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1 |
CNY 14,744.00 |
|
| RC224017L1 | Lenti-ORF clone of ABCC5 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1 |
CNY 17,144.00 |
|
| RC224017L2 | Lenti-ORF clone of ABCC5 (mGFP-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1 |
CNY 7,600.00 |
|
| RC224017L3 | Lenti-ORF clone of ABCC5 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1 |
CNY 17,144.00 |
|
| RC224017L4 | Lenti-ORF clone of ABCC5 (mGFP-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1 |
CNY 17,144.00 |
|
| RG224017 | ABCC5 (tGFP-tagged) - Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1 |
CNY 16,344.00 |
