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FOXM1 (NM_202002) Human Untagged Clone
CAT＃: SC308090
FOXM1 (untagged)-Human forkhead box M1 (FOXM1), transcript variant 1
CNY 8,808.00
| Cited in 6 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_202002 edited
GTGAAAACGCAGATTCATAATGAAAACTAGCCCCCGTCGGCCACTGATTCTCAAAAGACG GAGGCTGCCCCTTCCTGTTCAAAATGCCCCAAGTGAAACATCAGAGGAGGAACCTAAGAG ATCCCCTGCCCAACAGGAGTCTAATCAAGCAGAGGCCTCCAAGGAAGTGGCAGAGTCCAA CTCTTGCAAGTTTCCAGCTGGGATCAAGATTATTAACCACCCCACCATGCCCAACACGCA AGTAGTGGCCATCCCCAACAATGCTAATATTCACAGCATCATCACAGCACTGACTGCCAA GGGAAAAGAGAGTGGCAGTAGTGGGCCCAACAAATTCATCCTCATCAGCTGTGGGGGAGC CCCAACTCAGCCTCCAGGACTCCGGCCTCAAACCCAAACCAGCTATGATGCCAAAAGGAC AGAAGTGACCCTGGAGACCTTGGGACCAAAACCTGCAGCTAGGGATGTGAATCTTCCTAG ACCACCTGGAGCCCTTTGCGAGCAGAAACGGGAGACCTGTGCAGATGGTGAGGCAGCAGG CTGCACTATCAACAATAGCCTATCCAACATCCAGTGGCTTCGAAAGATGAGTTCTGATGG ACTGGGCTCCCGCAGCATCAAGCAAGAGATGGAGGAAAAGGAGAATTGTCACCTGGAGCA GCGACAGGTTAAGGTTGAGGAGCCTTCGAGACCATCAGCGTCCTGGCAGAACTCTGTGTC TGAGCGGCCACCCTACTCTTACATGGCCATGATACAATTCGCCATCAACAGCACTGAGAG GAAGCGCATGACTTTGAAAGACATCTATACGTGGATTGAGGACCACTTTCCCTACTTTAA GCACATTGCCAAGCCAGGCTGGAAGAACTCCATCCGCCACAACCTTTCCCTGCACGACAT GTTTGTCCGGGAGACGTCTGCCAATGGCAAGGTCTCCTTCTGGACCATTCACCCCAGTGC CAACCGCTACTTGACATTGGACCAGGTGTTTAAGCCACTGGACCCAGGGTCTCCACAATT GCCCGAGCACTTGGAATCACAGCAGAAACGACCGAATCCAGAGCTCCGCCGGAACATGAC CATCAAAACCGAACTCCCCCTGGGCGCACGGCGGAAGATGAAGCCACTGCTACCACGGGT CAGCTCATACCTGGTACCTATCCAGTTCCCGGTGAACCAGTCACTGGTGTTGCAGCCCTC GGTGAAGGTGCCATTGCCCCTGGCGGCTTCCCTCATGAGCTCAGAGCTTGCCCGCCATAG CAAGCGAGTCCGCATTGCCCCCAAGGTTTTTGGGGAACAGGTGGTGTTTGGTTACATGAG TAAGTTCTTTAGTGGCGATCTGCGAGATTTTGGTACACCCATCACCAGCTTGTTTAATTT TATCTTTCTTTGTTTATCAGTGCTGCTAGCTGAGGAGGGGATAGCTCCTCTTTCTTCTGC AGGACCAGGGAAAGAGGAGAAACTCCTGTTTGGAGAAGGGTTTTCTCCTTTGCTTCCAGT TCAGACTATCAAGGAGGAAGAAATCCAGCCTGGGGAGGAAATGCCACACTTAGCGAGACC CATCAAAGTGGAGAGCCCTCCCTTGGAAGAGTGGCCCTCCCCGGCCCCATCTTTCAAAGA GGAATCATCTCACTCCTGGGAGGATTCGTCCCAATCTCCCACCCCAAGACCCAAGAAGTC CTACAGTGGGCTTAGGTCCCCAACCCGGTGTGTCTCGGAAATGCTTGTGATTCAACACAG GGAGAGGAGGGAGAGGAGCCGGTCTCGGAGGAAACAGCATCTACTGCCTCCCTGTGTGGA TGAGCCGGAGCTGCTCTTCTCAGAGGGGCCCAGTACTTCCCGCTGGGCCGCAGAGCTCCC GTTCCCAGCAGACTCCTCTGACCCTGCCTCCCAGCTCAGCTACTCCCAGGAAGTGGGAGG ACCTTTTAAGACACCCATTAAGGAAACGCTGCCCATCTCCTCCACCCCGAGCAAATCTGT CCTCCCCAGAACCCCTGAATCCTGGAGGCTCACGCCCCCAGCCAAAGTAGGGGGACTGGA TTTCAGCCCAGTACAAACCTCCCAGGGTGCCTCTGACCCCTTGCCTGACCCCCTGGGGCT GATGGATCTCAGCACCACTCCCTTGCAAAGTGCTCCCCCCCTTGAATCACCGCAAAGGCT CCTCAGTTCAGAACCCTTAGACCTCATCTCCGTCCCCTTTGGCAACTCTTCTCCCTCAGA TATAGACGTCCCCAAGCCAGGCTCCCCGGAGCCACAGGTTTCTGGCCTTGCAGCCAATCG TTCTCTGACAGAAGGCCTGGTCCTGGACACAATGAATGACAGCCTCAGCAAGATCCTGCT GGACATCAGCTTTCCTGGCCTGGACGAGGACCCACTGGGCCCTGACAACATCAACTGGTC CCAGTTTATTCCTGAGCTACAGTAGAGCCCTGCCCTTGCCCCTGTGCTCAAGCTGTCCAC CATCCCGGGCACTCCAAGGCTCAGTGCACCCCAAGCCTCTGAGTGAGGACAGCAGGCAGG GACTGTTCTGCTCCTCATAGCTCCCTGCTGCCTGATTATGCAAAAGTAGCAGTCACACCC TAGCCACTGCTGGGACCTTGTGTTCCCCAAGAGTATCTGATTCCTCTGCTGTCCCTGCCA GGAGCTGAAGGGTGGGAACAACAAAGGCAATGGTGAAAAGAGATTAGGAACCCCCCAGCC TGTTTCCATTCTCTGCCCAGCAGTCTCTTACCTTCCCTGATCTTTGCAGGGTGGTCCGTG TAAATAGTATAAATTCTCCAAATTATCCTCTAATTATAAATGTAAGCTTATTTCCTTAGA TCATTATCCAGAGACTGCCAGAAGGTGGGTAGGATGACCTGGGGTTTCAATTGACTTCTG TTCCTTGCTTTTAGTTTTGATAGAAGGGAAGACCTGCAGTGCACGGTTTCTTCCAGGCTG AGGTACCTGGATCTTGGGTTCTTCACTGCAGGGACCCAGACAAGTGGATCTGCTTGCCAG AGTCCTTTTTGCCCCTCCCTGCCACCTCCCCGTGTTTCCAAGTCAGCTTTCCTGCAAGAA GAAATCCTGGTTAAAAAAGTCTTTTGTATTGGGTCAGGAGTTGAATTTGGGGTGGGAGGA TGGATGCAACTGAAGCAGAGTGTGGGTGCCCAGATGTGCGCTATTAGATGTTTCTCTGAT AATGTCCCCAATCATACCAGGGAGACTGGCATTGACGAGAACTCAGGTGGAGGCTTGAGA AGGCCGAAAGGGCCCCTGACCTGCCTGGCTTCCTTAGCTTGCCCCTCAGCTTTGCAAAGA GCCACCCTAGGCCCCAGCTGACCGCATGGGTGTGAGCCAGCTTGAGAACACTAACTACTC AATAAAAGCGAAGGTGGAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_202002 |
| Insert Size | 3500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | It is not a varient. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_202002.1, NP_973731.1 |
| RefSeq Size | 3641 bp |
| RefSeq ORF | 2406 bp |
| Locus ID | 2305 |
| UniProt ID | Q08050 |
| Protein Families | Transcription Factors |
| Gene Summary | The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Citations (6)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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FOXM1 contributes to taxane resistance by regulating UHRF1-controlled cancer cell stemness
,Yuan, B;Liu, Y;Yu, X;Yin, L;Peng, Y;Gao, Y;Zhu, Q;Cao, T;Yang, Y;Fan, X;Li, X;,
Cell Death Dis
,PubMed ID 29752436
[FOXM1]
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FOXM1 promotes the progression of prostate cancer by regulating PSA gene transcription
,Liu, Y;Liu, Y;Yuan, B;Yin, L;Peng, Y;Yu, X;Zhou, W;Gong, Z;Liu, J;He, L;Li, X;,
Oncotarget
,PubMed ID 28199985
[FOXM1]
|
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Insulin-like growth factor-1 receptor signaling increases the invasive potential of HER2-overexpressing breast cancer cells via Src-FAK and FoxM1
,Sanabria-Figueroa, E;Donnelly, S;Foy, K;Buss, M;Castellino, RC;Paplomata, E;Taliaferro-Smith, L;Kaumaya, P;Nahta, R;,
Mol. Pharmacol.
,PubMed ID 25391374
[FOXM1]
|
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Phenotype-assisted transcriptome analysis identifies FOXM1 downstream from Ras–MKK3–p38 to regulate in vitro cellular invasion
,A Behren, S Mühlen, G A Acuna Sanhueza, C Schwager, P K Plinkert, P E Huber, A Abdollahi, C Simon,
Oncogene (21 December 2009) doi:10.1038/onc.2009.436 Original Article
[FOXM1]
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Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC
,D F Calvisi, F Pinna, S Ladu, R Pellegrino, M M Simile, M Frau, M R De Miglio, M L Tomasi, V Sanna, M R Muroni, F Feo, and R M Pascale,
Gut, May 2009; 58: 679 - 687.
[FOXM1]
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Down-regulation of Forkhead Box M1 Transcription Factor Leads to the Inhibition of Invasion and Angiogenesis of Pancreatic Cancer Cells
,Z Wang, S Banerjee, D Kong, Y Li, and FH Sarkar,
Cancer Res. 2007 Sep 1;67(17):8293-300.
[FOXM1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211450 | FOXM1 (Myc-DDK-tagged)-Human forkhead box M1 (FOXM1), transcript variant 1 |
CNY 8,800.00 |
|
| RC211450L1 | Lenti-ORF clone of FOXM1 (Myc-DDK-tagged)-Human forkhead box M1 (FOXM1), transcript variant 1 |
CNY 11,200.00 |
|
| RC211450L2 | Lenti-ORF clone of FOXM1 (mGFP-tagged)-Human forkhead box M1 (FOXM1), transcript variant 1 |
CNY 10,360.00 |
|
| RC211450L3 | Lenti-ORF clone of FOXM1 (Myc-DDK-tagged)-Human forkhead box M1 (FOXM1), transcript variant 1 |
CNY 11,200.00 |
|
| RC211450L4 | Lenti-ORF clone of FOXM1 (mGFP-tagged)-Human forkhead box M1 (FOXM1), transcript variant 1 |
CNY 11,200.00 |
|
| RG211450 | FOXM1 (tGFP-tagged) - Human forkhead box M1 (FOXM1), transcript variant 1 |
CNY 10,400.00 |
