KCNK18 (NM_181840) Human Untagged Clone
CAT#: SC307384
KCNK18 (untagged)-Human potassium channel, subfamily K, member 18 (KCNK18)
CNY 3,656.00
CNY 6,270.00
Cited in 2 publications. |
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | K2p18.1; MGR13; TRESK; TRESK-2; TRESK2; TRIK |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_181840 edited
ATGGAGGTCTCGGGGCACCCCCAGGCCAGGAGATGCTGCCCAGAGGCCCTGGGAAAGCTC TTCCCTGGCCTCTGCTTCCTCTGCTTTCTGGTGACCTACGCCCTGGTGGGTGCTGTGGTC TTCTCTGCCATTGAGGACGGCCAGGTCCTGGTGGCAGCAGATGATGGAGAGTTTGAGAAG TTCTTGGAGGAGCTCTGCAGAATCTTGAACTGCAGTGAAACAGTGGTGGAAGACAGAAAA CAGGATCTCCAGGGGCATCTGCAGAAGGTGAAGCCTCAGTGGTTTAACAGGACCACACAC TGGTCCTTCCTGAGCTCGCTCTTTTTCTGCTGCACGGTGTTCAGCACCGTGGGCTATGGC TACATCTACCCCGTCACCAGGCTTGGCAAGTACTTGTGCATGCTCTATGCTCTCTTTGGT ATCCCCCTGATGTTCCTCGTTCTCACGGACACAGGCGACATCCTGGCAACCATCTTATCT ACATCTTATAATCGGTTCCGAAAATTCCCTTTCTTTACCCGCCCCCTCCTCTCCAAGTGG TGCCCCAAATCTCTCTTCAAGAAAAAACCGGACCCCAAGCCCGCAGATGAAGCTGTCCCT CAGATCATCATCAGTGCTGAAGAGCTTCCAGGCCCCAAACTTGGCACATGTCCTTCACGC CCAAGCTGCAGCATGGAGCTGTTTGAGAGATCTCATGCGCTAGAGAAACAGAACACACTG CAACTGCCCCCACAAGCCATGGAGAGGAGTAACTCGTGTCCCGAACTGGTGTTGGGAAGA CTCTCATACTCCATCATCAGCAACCTGGATGAAGTTGGACAGCAGGTGGAGAGGTTGGAC ATCCCCCTCCCCATCATTGCCCTTATTGTTTTTGCCTACATTTCCTGTGCAGCTGCCATC CTCCCCTTCTGGGAGACACAGTTGGATTTCGAGAATGCCTTCTATTTCTGCTTTGTCACA CTCACCACCATTGGGTTTGGGGATACTGTTTTAGAACACCCTAACTTCTTCCTGTTCTTC TCCATTTATATCATCGTTGGAATGGAGATTGTGTTCATTGCTTTCAAGTTGGTGCAAAAC AGGCTGATTGACATATACAAAAATGTTATGCTATTCTTTGCAAAAGGGAAGTTTTACCAC CTTGTTAAAAAGTGACTCGA >OriGene 5' read for NM_181840 unedited
GTTAAGGTTAGATTTGTATACCATTACTATAGGCGGCCGCCATTCTGGNAGTCTCGGGGC ACCCCCAGGCCAGGAGATGCTGCCCAGAGGCCCTGGGAAAGCTCTTCCCTGGCCTCTGCT TCCTCTGCTTTCTGGTGACCTACGCCCTGGTGGGTGCTGTGGTCTTCTCTGCCATTGAGG ACGGCCAGGTCCTGGTGGCAGCAGATGATGGAGAGTTTGAGAAGTTCTTGGAGGAGCTCT GCAGAATCTTGAACTGCAGTGAAACAGTGGTGGAAGACAGAAAACAGGATCTCCAGGGGC ATCTGCAGAAGGTGAAGCCTCAGTGGTTTAACAGGACCACACACTGGTCCTTCCTGAGCT CGCTCTTTTTCTGCTGCACGGTGTTCAGCACCGTGGGCTATGGCTACATCTACCCCGTCA CCAGGCTTGGCAAGTACTTGTGCATGCTCTATGCTCTCTTTGGTATCCCCCTGATGTTCC TCGTTCTCACGGACACAGGCGACATCCTGGCAACCATCTTATCTACATCTTATAATCGGT TCCGAAAATTCCCTTTCTTTACCCGCCCCCTCCTCTCCAAGTGGTGCCCCAAATCTCTCT TCAAGAAAAAACCGGACCCCAAGCCCGCAGATGAAGCTGTCCCTCAGATCATCATCAGTG CTGAAGAGCTTCCAGGCCCCAAACTTGGCACATGTCCTTCACGCCCAAGCTGCAGCATGG AGCTGTTTGAGAGATCTCATGCGCTAGAGAAACAGAACACACTGCAACTGCCCCCACAAG CCATGGAGAGGAGTAACTCGTGTCCCGAACTGGTGTTGGGAAGACTCTCATACTCCATCA TCAGCAACCTGGATGAAGTTGGACAGCNAGTGGAGAAGTTGGACATN |
Restriction Sites | Please inquire |
ACCN | NM_181840 |
Insert Size | 1200 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_181840.1, NP_862823.1 |
RefSeq Size | 1155 bp |
RefSeq ORF | 1155 bp |
Locus ID | 338567 |
UniProt ID | Q7Z418 |
Protein Families | Ion Channels: Potassium, Transmembrane |
Gene Summary | Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains and the encoded protein functions as an outward rectifying potassium channel. A mutation in this gene has been found to be associated with migraine with aura.[provided by RefSeq, Jan 2011] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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Identification of novel small molecule modulators of K2P18.1 two-pore potassium channel
,Bruner, JK;Zou, B;Zhang, H;Zhang, Y;Schmidt, K;Li, M;,
Eur. J. Pharmacol.
,PubMed ID 24972239
[KCNK18]
|
Noradrenergic depression of neuronal excitability in the entorhinal cortex via activation of TREK-2 K+ channels
,MECHANISMS OF SIGNAL TRANSDUCTION: Noradrenergic depression of neuronal excitability in the entorhinal cortex via activation of TREK-2 K+ channels Zhaoyang Xiao, Pan-Yue Deng, Lalida Rojanathammanee, Chuanxiu Yang, Laurel Grisanti, Kannika Permpoonputtana, David Weinshenker, Van A. Doze, James E. Porter, and Saobo Lei,
J. Biol. Chem., Feb 2009; 10.1074/jbc.M806760200.
[KCNK18]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC212920 | KCNK18 (Myc-DDK-tagged)-Human potassium channel, subfamily K, member 18 (KCNK18) |
CNY 3,656.00 |
|
RC212920L1 | Lenti ORF clone of Human potassium channel, subfamily K, member 18 (KCNK18), Myc-DDK-tagged |
CNY 6,056.00 |
|
RC212920L2 | Lenti ORF clone of Human potassium channel, subfamily K, member 18 (KCNK18), mGFP tagged |
CNY 6,056.00 |
|
RC212920L3 | Lenti ORF clone of Human potassium channel, subfamily K, member 18 (KCNK18), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC212920L4 | Lenti ORF clone of Human potassium channel, subfamily K, member 18 (KCNK18), mGFP tagged |
CNY 5,890.00 |
|
RG212920 | KCNK18 (tGFP-tagged) - Human potassium channel, subfamily K, member 18 (KCNK18) |
CNY 5,256.00 |