United States
Germany
Japan
United Kingdom
China
NALP5 (NLRP5) (NM_153447) Human Untagged Clone
CAT＃: SC306608
NLRP5 (untagged)-Human NLR family, pyrin domain containing 5 (NLRP5)
CNY 12,344.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CLR19.8; MATER; NALP5; PAN11; PYPAF8 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_153447 edited
ATGAAGGTTGCAGGAGGACTTGAACTTGGAGCTGCTGCTCTGCTCTCAGCATCACCACGT GCTCTTGTCACTCTTTCCACAGGTCCTACTTGCTCTATATTACCAAAGAATCCACTTTTC CCCCAAAACCTGAGCTCTCAGCCTTGTATCAAGATGGAAGGAGACAAATCGCTCACCTTT TCCAGCTACGGGCTGCAATGGTGTCTCTATGAGCTAGACAAGGAAGAATTTCAGACATTC AAGGAATTACTAAAGAAGAAATCTTCAGAATCGACCACATGCTCTATTCCACAGTTTGAA ATCGAGAATGCCAACGTGGAATGTCTGGCACTCCTCTTGCATGAGTATTATGGAGCATCG CTGGCCTGGGCTACGTCCATTAGCATCTTTGAAAACATGAACCTGCGAACCCTCTCGGAG AAGGCACGGGATGACATGAAAAGACATTCACCAGAAGATCCTGAAGCAACGATGACTGAC CAAGGACCAAGCAAGGAAAAAGTGCCAGGAATTTCACAAGCTGTGCAACAAGATAGTGCC ACAGCTGCAGAGACAAAAGAACAAGAAATTTCACAAGCTATGGAACAAGAAGGTGCCACA GCAGCAGAGACAGAAGAACAAGGACATGGAGGTGACACATGGGACTACAAGAGTCACGTG ATGACCAAATTCGCTGAGGAGGAGGATGTACGTCGTAGTTTTGAAAACACTGCTGCTGAC TGGCCGGAAATGCAAACGTTGGCTGGTGCTTTTGATTCAGACCGGTGGGGCTTCCGGCCT CGCACGGTGGTTCTGCACGGAAAGTCAGGAATTGGGAAATCGGCTCTAGCCAGAAGGATC GTGCTGTGCTGGGCGCAAGGTGGACTCTACCAGGGAATGTTCTCCTACGTCTTCTTCCTC CCCGTTAGAGAGATGCAGCGGAAGAAGGAGAGCAGTGTCACAGAGTTCATCTCCAGGGAG TGGCCAGACTCCCAGGCTCCGGTGACGGAGATCATGTCCCGACCAGAAAGGCTGTTGTTC ATCATTGACGGTTTCGATGACCTGGGCTCTGTCCTCAACAATGACACAAAGCTCTGCAAA GACTGGGCTGAGAAGCAGCCTCCGTTCACCCTCATACGCAGTCTGCTGAGGAAGGTCCTG CTCCCTGAGTCCTTCCTGATCGTCACCGTCAGAGACGTGGGCACAGAGAAGCTCAAGTCA GAGGTCGTGTCTCCCCGTTACCTGTTAGTTAGAGGAATCTCCGGGGAACAAAGAATCCAC TTGCTCCTTGAGCGCGGGATTGGTGAGCATCAGAAGACACAAGGGTTGCGTGCGATCATG AACAACCGTGAGCTGCTCGACCAGTGCCAGGTGCCCGCCGTGGGCTCTCTCATCTGCGTG GCCCTGCAGCTGCAGGACGTGGTGGGGGAGAGCGTCGCCCCCTTCAACCAAACGCTCACA GGCCTGCACGCCGCTTTTGTGTTTCATCAGCTCACCCCTCGAGGCGTGGTCCGGCGCTGT CTCAATCTGGAGGAAAGAGTTGTCCTGAAGCGCTTCTGCCGTATGGCTGTGGAGGGAGTG TGGAATAGGAAGTCAGTGTTTGACGGTGACGACCTCATGGTTCAAGGACTCGGGGAGTCT GAGCTCCGTGCTCTGTTTCACATGAACATCCTTCTCCCAGACAGCCACTGTGAGGAGTAC TACACCTTCTTCCACCTCAGTCTCCAGGACTTCTGTGCCGCCTTGTACTACGTGTTAGAG GGCCTGGAAATCGAGCCAGCTCTCTGCCCTCTGTACGTTGAGAAGACAAAGAGGTCCATG GAGCTTAAACAGGCAGGCTTCCATATCCACTCGCTTTGGATGAAGCGTTTCTTGTTTGGC CTCGTGAGCGAAGACGTAAGGAGGCCACTGGAGGTCCTGCTGGGCTGTCCCGTTCCCCTG GGGGTGAAGCAGAAGCTTCTGCACTGGGTCTCTCTGTTGGGTCAGCAGCCTAATGCCACC ACCCCAGGAGACACCCTGGACGCCTTCCACTGTCTTTTCGAGACTCAAGACAAAGAGTTT GTTCGCTTGGCATTAAACAGCTTCCAAGAAGTGTGGCTTCCGATTAACCAGAACCTGGAC TTGATAGCATCTTCCTTCTGCCTCCAGCACTGTCCGTATTTGCGGAAAATTCGGGTGGAT GTCAAAGGGATCTTCCCAAGAGATGAGTCCGCTGAGGCATGTCCTGTGGTCCCTCTATGG ATGCGGGATAAGACCCTCATTGAGGAGCAGTGGGAAGATTTCTGCTCCATGCTTGGCACC CACCCACACCTGCGGCAGCTGGACCTGGGCAGCAGCATCCTGACAGAGCGGGCCATGAAG ACCCTGTGTGCCAAGCTGAGGCATCCCACCTGCAAGATACAGACCCTGATGTTTAGAAAT GCACAGATTACCCCTGGTGTGCAGCACCTCTGGAGAATCGTCATGGCCAACCGTAACCTA AGATCCCTCAACTTGGGAGGCACCCACCTGAAGGAAGAGGATGTAAGGATGGCGTGTGAA GCCTTAAAACACCCAAAATGTTTGTTGGAGTCTTTGAGGCTGGATTGCTGTGGATTGACC CATGCCTGTTACCTGAAGATCTCCCAAATCCTTACGACCTCCCCCAGCCTGAAATCTCTG AGCCTGGCAGGAAACAAGGTGACAGACCAGGGAGTAATGCCTCTCAGTGATGCCTTGAGA GTCTCCCAGTGCGCCCTGCAGAAGCTGATACTGGAGGACTGTGGCATCACAGCCACGGGT TGCCAGAGTCTGGCCTCAGCCCTCGTCAGCAACCGGAGCTTGACACACCTGTGCCTATCC AACAACAGCCTGGGGAACGAAGGTGTAAATCTACTGTGTCGATCCATGAGGCTTCCCCAC TGTAGTCTGCAGAGGCTGATGCTGAATCAGTGCCACCTGGACACGGCTGGCTGTGGTTTT CTTGCACTTGCGCTTATGGGTAACTCATGGCTGACGCACCTGAGCCTTAGCATGAACCCT GTGGAAGACAATGGCGTGAAGCTTCTGTGCGAGGTCATGAGAGAACCATCTTGTCATCTC CAGGACCTGGAGTTGGTAAAGTGTCATCTCACCGCCGCGTGCTGTGAGAGTCTGTCCTGT GTGATCTCGAGGAGCAGACACCTGAAGAGCCTGGATCTCACGGACAATGCCCTGGGTGAC GGTGGGGTTGCTGCGCTGTGCGAGGGACTGAAGCAAAAGAACAGTGTTCTGGCGAGACTC GGGTTGAAGGCATGTGGACTGACTTCTGATTGCTGTGAGGCACTCTCCTTGGCCCTTTCC TGCAACCGGCATCTGACCAGTCTAAACCTGGTGCAGAATAACTTCAGTCCCAAAGGAATG ATGAAGCTGTGTTCGGCCTTTGCCTGTCCCACGTCTAACTTACAGATAATTGGGCTGTGG AAATGGCAGTACCCTGTGCAAATAAGGAAGCTGCTGGAGGAAGTGCAGCTACTCAAGCCC CGAGTCGTAATTGACGGTAGTTGGCATTCTTTTGATGAAGATGACCGGTACTGGTGGAAA AACTGA >OriGene 5' read for NM_153447 unedited
TTGCAGGAGGACTTGAACTTGGAGCTGCTGCTCTGCTCTCAGCATCACCACGTGCTCTTG TCACTCTTTCACAGGTCCTACTTGCTCTATATTACCAAAGAATCCACTTTTCCCCCAAAA CCTGAGCTCTCAGCCTTGTATCAAGATGGAAGGAGACAAATCGCTCACCTTTTCCAGCTA CGGGCTGCAATGGTGTCTCTATGAGCTAGACAAGGAAGAATTTCAGACATTCAAGGAATT ACTAAAGAAGAAATCTTCAGAATCGACCACATGCTCTATTCCACAGTTTGAAATCGAGAA TGCCAACGTGGAATGTCTGGCACTCCTCTTGCATGAGTATTATGGAGCATCGCTGGCCTG GGCTACGTCCATTAGCATCTTTGAAAACATGAACCTGCGAACCCTCTCGGAGAAGGCACG GGATGACATGAAAAGACATTCACCAGAAGATCCTGAAGCAACGATGACTGACCAAGGACC AAGCAAGGAAAAAGTGCCAGGAATTTCACAAGCTGTGCAACAAGATAGTGCCACAGCTGC AGAGACAAAAGAACAAGANATTTCACAAGCTATGGAACAGGAAGGTGCCACAGCAGCAGA GACAGAAGAACAGGACATGGGAGTGACACATGGGACTACAAGAGTCACGTGATGACCAAA TTCGCTGAGGAGGGAGGATGTACGTCATAGTTTTGGAAACACTGCTGCTGACTGGCCCGG AATGCAAACGTTGGCTGGTGCTTTTGATTCAGACCGGTGGGGGCTTCCGGCCTCGCACGG |
| Restriction Sites | Please inquire |
| ACCN | NM_153447 |
| Insert Size | 3500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_153447.3, NP_703148.3 |
| RefSeq Size | 3828 bp |
| RefSeq ORF | 3546 bp |
| Locus ID | 126206 |
| UniProt ID | P59047 |
| Gene Summary | The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. [provided by RefSeq, Jul 2008] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Autoantibody response against NALP5/MATER in primary ovarian insufficiency and in autoimmune Addison's disease
,Brozzetti, A;Alimohammadi, M;Morelli, S;Minarelli, V;Hallgren, Å;Giordano, R;De Bellis, A;Perniola, R;Kämpe, O;Falorni, A;on behalf of the Italian Addison Network, ;,
J. Clin. Endocrinol. Metab.
,PubMed ID 25734249
[NLRP5]
|
|
Prevalence and significance of NALP5 autoantibodies in patients with idiopathic hypoparathyroidism.
,null,
The Journal of clinical endocrinology and metabolism
,PubMed ID 22278434
[NLRP5]
|
|
Prevalence and Significance of NALP5 Autoantibodies in Patients with Idiopathic Hypoparathyroidism
,Neeraj Tomar, Esha Kaushal, Madhuchhanda Das, Nandita Gupta, Corrado Betterle, and Ravinder Goswami,
J. Clin. Endocrinol. Metab., Apr 2012; 97: 1219 - 1226.
[NLRP5]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223877 | NLRP5 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 12,528.00 |
|
| RC223877L1 | Lenti-ORF clone of NLRP5 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 14,928.00 |
|
| RC223877L2 | Lenti-ORF clone of NLRP5 (mGFP-tagged)-Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 11,500.00 |
|
| RC223877L3 | Lenti-ORF clone of NLRP5 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 11,500.00 |
|
| RC223877L4 | Lenti-ORF clone of NLRP5 (mGFP-tagged)-Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 11,500.00 |
|
| RG223877 | NLRP5 (tGFP-tagged) - Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 14,128.00 |
|
| SC318548 | NLRP5 (untagged)-Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 12,544.00 |
