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Jagged 2 (JAG2) (NM_145159) Human Untagged Clone
CAT＃: SC306220
JAG2 (untagged)-Human jagged 2 (JAG2), transcript variant 2
CNY 23,090.00
货期*
详询
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HJ2; SER2 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_145159, the custom clone sequence may differ by one or more nucleotides
ATGCGGGCGCAGGGCCGGGGGCGCCTTCCCCGGCGGCTGCTGCTGCTGCTGGCGCTCTGG GTGCAGGCGGCGCGGCCCATGGGCTATTTCGAGCTGCAGCTGAGCGCGCTGCGGAACGTG AACGGGGAGCTGCTGAGCGGCGCCTGCTGTGACGGCGACGGCCGGACAACGCGCGCGGGG GGCTGCGGCCACGACGAGTGCGACACGTACGTGCGCGTGTGCCTTAAGGAGTACCAGGCC AAGGTGACGCCCACGGGGCCCTGCAGCTACGGCCACGGCGCCACGCCCGTGCTGGGCGGC AACTCCTTCTACCTGCCGCCGGCGGGCGCTGCGGGGGACCGAGCGCGGGCGCGGGCCCGG GCCGGCGGCGACCAGGACCCGGGCCTCGTCGTCATCCCCTTCCAGTTCGCCTGGCCGCGC TCCTTTACCCTCATCGTGGAGGCCTGGGACTGGGACAACGATACCACCCCGAATGAGGAG CTGCTGATCGAGCGAGTGTCGCATGCCGGCATGATCAACCCGGAGGACCGCTGGAAGAGC CTGCACTTCAGCGGCCACGTGGCGCACCTGGAGCTGCAGATCCGCGTGCGCTGCGACGAG AACTACTACAGCGCCACTTGCAACAAGTTCTGCCGGCCCCGCAACGACTTTTTCGGCCAC TACACCTGCGACCAGTACGGCAACAAGGCCTGCATGGACGGCTGGATGGGCAAGGAGTGC AAGGAAGCTGTGTGTAAACAAGGGTGTAATTTGCTCCACGGGGGATGCACCGTGCCTGGG GAGTGCAGGTGCAGCTACGGCTGGCAAGGGAGGTTCTGCGATGAGTGTGTCCCCTACCCC GGCTGCGTGCATGGCAGTTGTGTGGAGCCCTGGCAGTGCAACTGTGAGACCAACTGGGGC GGCCTGCTCTGTGACAAAGACCTGAACTACTGTGGCAGCCACCACCCCTGCACCAACGGA GGCACGTGCATCAACGCCGAGCCTGACCAGTACCGCTGCACCTGCCCTGACGGCTACTCG GGCAGGAACTGTGAGAAGGCTGAGCACGCCTGCACCTCCAACCCGTGTGCCAACGGGGGC TCTTGCCATGAGGTGCCGTCCGGCTTCGAATGCCACTGCCCATCGGGCTGGAGCGGGCCC ACCTGTGCCCTTGACATCGATGAGTGTGCTTCGAACCCGTGTGCGGCCGGTGGCACCTGT GTGGACCAGGTGGACGGCTTTGAGTGCATCTGCCCCGAGCAGTGGGTGGGGGCCACCTGC CAGCTGGACGTCAACGACTGTCGCGGGCAGTGTCAGCATGGGGGCACCTGCAAGGACCTG GTGAACGGGTACCAGTGTGTGTGCCCACGGGGCTTCGGAGGCCGGCATTGCGAGCTGGAA CGAGACGAGTGTGCCAGCAGCCCCTGCCACAGCGGCGGCCTCTGCGAGGACCTGGCCGAC GGCTTCCACTGCCACTGCCCCCAGGGCTTCTCCGGGCCTCTCTGTGAGGTGGATGTCGAC CTTTGTGAGCCAAGCCCCTGCCGGAACGGCGCTCGCTGCTATAACCTGGAGGGTGACTAT TACTGCGCCTGCCCTGATGACTTTGGTGGCAAGAACTGCTCCGTGCCCCGCGAGCCGTGC CCTGGCGGGGCCTGCAGAGTGATCGATGGCTGCGGGTCAGACGCGGGGCCTGGGATGCCT GGCACAGCAGCCTCCGGCGTGTGTGGCCCCCATGGACGCTGCGTCAGCCAGCCAGGGGGC AACTTTTCCTGCATCTGTGACAGTGGCTTTACTGGCACCTACTGCCATGAGAACATTGAC GACTGCCTGGGCCAGCCCTGCCGCAATGGGGGCACATGCATCGATGAGGTGGACGCCTTC CGCTGCTTCTGCCCCAGCGGCTGGGAGGGCGAGCTCTGCGACACCAATCCCAACGACTGC CTTCCCGATCCCTGCCACAGCCGCGGCCGCTGCTACGACCTGGTCAATGACTTCTACTGT GCGTGCGACGACGGCTGGAAGGGCAAGACCTGCCACTCACGCGAGTTCCAGTGCGATGCC TACACCTGCAGCAACGGTGGCACCTGCTACGACAGCGGCGACACCTTCCGCTGCGCCTGC CCCCCCGGCTGGAAGGGCAGCACCTGCGCCGTCGCCAAGAACAGCAGCTGCCTGCCCAAC CCCTGTGTGAATGGTGGCACCTGCGTGGGCAGCGGGGCCTCCTTCTCCTGCATCTGCCGG GACGGCTGGGAGGGTCGTACTTGCACTCACAATACCAACGACTGCAACCCTCTGCCTTGC TACAATGGTGGCATCTGTGTTGACGGCGTCAACTGGTTCCGCTGCGAGTGTGCACCTGGC TTCGCGGGGCCTGACTGCCGCATCAACATCGACGAGTGCCAGTCCTCGCCCTGTGCCTAC GGGGCCACGTGTGTGGATGAGATCAACGGGTATCGCTGTAGCTGCCCACCCGGCCGAGCC GGCCCCCGGTGCCAGGAAGTGATCGGGTTCGGGAGATCCTGCTGGTCCCGGGGCACTCCG TTCCCACACGGAAGCTCCTGGGTGGAAGACTGCAACAGCTGCCGCTGCCTGGATGGCCGC CGTGACTGCAGCAAGGTGTGGTGCGGATGGAAGCCTTGTCTGCTGGCCGGCCAGCCCGAG GCCCTGAGCGCCCAGTGCCCACTGGGGCAAAGGTGCCTGGAGAAGGCCCCAGGCCAGTGT CTGCGACCACCCTGTGAGGCCTGGGGGGAGTGCGGCGCAGAAGAGCCACCGAGCACCCCC TGCCTGCCACGCTCCGGCCACCTGGACAATAACTGTGCCCGCCTCACCTTGCATTTCAAC CGTGACCACGTGCCCCAGGGCACCACGGTGGGCGCCATTTGCTCCGGGATCCGCTCCCTG CCAGCCACAAGGGCTGTGGCACGGGACCGCCTGCTGGTGTTGCTTTGCGACCGGGCGTCC TCGGGGGCCAGTGCCGTGGAGGTGGCCGTGTCCTTCAGCCCTGCCAGGGACCTGCCTGAC AGCAGCCTGATCCAGGGCGCGGCCCACGCCATCGTGGCCGCCATCACCCAGCGGGGGAAC AGCTCACTGCTCCTGGCTGTCACCGAGGTCAAGGTGGAGACGGTTGTTACGGGCGGCTCT TCCACAGGTCTGCTGGTGCCTGTGCTGTGTGGTGCCTTCAGCGTGCTGTGGCTGGCGTGC GTGGTCCTGTGCGTGTGGTGGACACGCAAGCGCAGGAAAGAGCGGGAGAGGAGCCGGCTG CCGCGGGAGGAGAGCGCCAACAACCAGTGGGCCCCGCTCAACCCCATCCGCAACCCCATC GAGCGGCCGGGGGGCCACAAGGACGTGCTCTACCAGTGCAAGAACTTCACGCCGCCGCCG CGCAGGGCGGACGAGGCGCTGCCCGGGCCGGCCGGCCACGCGGCCGTCAGGGAGGATGAG GAGGACGAGGATCTGGGCCGCGGTGAGGAGGACTCCCTGGAGGCGGAGAAGTTCCTCTCA CACAAATTCACCAAAGATCCTGGCCGCTCGCCGGGGAGGCCGGCCCACTGGGCCTCAGGC CCCAAAGTGGACAACCGCGCGGTCAGGAGCATCAATGAGGCCCGCTACGCCGGCAAGGAG TAG |
| Restriction Sites | Please inquire |
| ACCN | NM_145159 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_145159.1, NP_660142.1 |
| RefSeq Size | 4963 bp |
| RefSeq ORF | 3603 bp |
| Locus ID | 3714 |
| UniProt ID | Q9Y219 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Notch signaling pathway |
| Gene Summary | The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1, resulting in a shorter protein (isoform b) than isoform a encoded by variant 1. Isoform b is also known as hJAG2.del-E6. |
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